Henry's research interests are grouped into four thematic areas:

• Antimicrobials surfaces for biomedical implant devices and frequently touched infection-prone area applications. In particular, design, fabrication and validation of: (a) Anti-biofouling surfaces that repel bacterial attachment, and bactericidal surfaces that kill bacteria by releasing biocides or by mechanical stresses mechano-bactericidal surfaces; (b) Mechano-biology and surface modification of biomaterials. Specifically, understanding how cells respond to physical and mechanical stimuli at the micro and nanoscale to modulate favourable biological response.

• Electrochemistry of the nervous systems and biodegradable metals for Biomedical device implant applications. Particularly, Henry’s interest focuses on: (a) Electrochemical sensors for monitoring, detection and medical diagnostics; (b) The design, fabrication and validation of electrochemical bioresorbable and biodegradable Mg, Zn and Fe metallic biomaterials for biomedical implants; (c) Electroforming-driven 3D addictive manufacturing

• Water Purification, Energy and Environment. Henry's interest is focused on electrochemical and Visible-light active driven catalysis for (a) Water purification (point-of-use water filters); (b) Artificial leaf photosynthesis; (c) Water splitting hydrogen production for fuel cell technology; and (d) Environmental remediation (mining effluent and oil spill detoxification)

• Henry's research interest focuses on the dynamic intersection of Biotechnology and Metals extraction. Specifically, investigating microbial-driven techniques (bioleaching and bioflotation) in the extraction of metals from refractory ores. His research also aims at understanding the metabolism pathways and mechanisms employed by different strains of microorganisms in biooxidation and bioleaching of refractory ores (sulfide minerals). Henry employs a multidisciplinary approach (integrating microbiology, molecular biology, mineral processing, micro and nanotechnology, and materials science and engineering) to characterize microbial communities and elucidate their functional roles in altering mineral surfaces for efficient, cost effective and eco-friendly metal extraction, reducing the reliance on environmentally detrimental chemical processes.