Dr. Clement Osei Akoto

Senior Lecturer

Dept: Chemistry
Dr. Clement Osei Akoto, Senior Research Scientist
Department of Chemistry,
KNUST - Kumasi
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Research Areas/Interests

Areas of Specialization: Organic and Bioorganic Chemistry, Pharmaceutical and Medicinal Chemistry, Spectroscopic Chemistry, Organometallic Chemis...~more

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Publications

    SELECTED PUBLICATIONS:

    1. Vigbedor, B. Y., Osei Akoto, C.,Neglo, D. "Isolation and Identification of Flavanone Derivative Eriodictyol from the Methanol Extract of Afzelia africana Bark and Its Antimicrobial and Antioxidant Activities", Evidence-Based Complementary and Alternative Medicine, vol. 2023, Article ID 9345047, 12 pages, 2023. https://doi.org/10.1155/2023/9345047
    2. Vigbedor, B. Y., Osei Akoto, C.,Neglo, D. "Isolation and characterization of 3,3'-di-O-methyl ellagic acid from the root bark of Afzelia africana and its antimicrobial and antioxidant activities". Scientific African, Volume 17, 2022, e01332, ISSN 2468-2276, https://doi.org/10.1016/j.sciaf.2022.e01332.
    3. Amanfo, Adwoa Frema; Kyei, Samuel; Boakye, Yaw Duah; Osei Akoto, Clement; Addo, Justice Kwaku; Yeboah, Kofi Oduro; Osafo, Newman. "The Aqueous Stem Bark Extract of Alstonia boonei Exhibits Anticataract Activity in Sprague Dawley Rat", Scientifica, vol. 2023, Article ID 5524137, 12 pages, 2023. https://doi.org/10.1155/2023/5524137.
    4. Osei Akoto, C., Rainier, J. D. “Concise Seven-Membered Oxepene/Oxepane Synthesis – Structural Motifs in Natural and Synthetic Products”. Synthesis 2019; 51(18): 3529-3535. DOI: 10.1055/s-0037-1611838.
    5. Amanfo, Adwoa Frema; Kyei, Samuel; Boakye, Yaw Duah; Osei Akoto, Clement; Addo, Justice Kwaku; Yeboah, Kofi Oduro; Osafo, Newman. "Anticataract Effect of the Aqueous Extract of the Flowers of Aspilia africana in Murine Model of Diabetic and Age-Related Cataracts", Advances in Pharmacological and Pharmaceutical Sciences, vol. 2023, Article ID 7867497, 14 pages, 2023. https://doi.org/10.1155/2023/7867497.
    6. Osei Akoto C., Adzimah ME, Forkuoh AY, Obedi P, Oguns J, Boahen FO."Cytotoxicity, Antimicrobial, Antioxidant, Anthelmintic, and Anti-Inflammatory Activities and FTIR Analysis of Combretum nioroense Stem Bark", Journal of Chemistry. vol. 2023, Article ID 5424386, 14 pages, 2023. https://doi.org/10.1155/2023/5424386.
    7. Douvris C, Bentil E, Ayensu I, Osei Akoto C, Amponsah IK, Adu J, Bussan D. "Trace Metals in Cannabis Seized by Law Enforcement in Ghana and Multivariate Analysis to Distinguish among Different Cannabis Farms." Toxics. 2022; 10(10):567. https://doi.org/10.3390/toxics10100567.
    8. Vigbedor, Bright Yaw, Osei Akoto, Clement, Kwakye, Ralph, Osei-Owusu, Jonathan, Neglo, David, Kwashie, Pius."Antioxidant, antibacterial, antifungal activities and gas chromatographic fingerprint of fractions from the root bark of Afzelia africana". Int J Biochem Mol Biol 2022;13(6):60-76.
    9. Osei Akoto C, Acheampong A, Boakye YD, Asante B, Ohene S, Amankwah F. Anthelminthic, Anti-Inflammatory, Antioxidant, and Antimicrobial Activities and FTIR Analyses of Vernonia camporum Stem-Bark. Journal of Chemistry, vol. 2021, Article ID 3328073, 15 pages, 2021. https://doi.org/10.1155/2021/3328073. 
    10. Osei Akoto, C and Rainier, J. D. “Harnessing Glycal Epoxide Rearrangement: The Generation of the AB, EF, and IJ Rings of Adriatoxin.” Angew. Chem. Int. Ed. 2008, 47, 8055-8058.
    11. Zhao, Y., Slepkov, A. D., ,Osei Akoto C., McDonald, R., Hegmann, F. A., Tykwinski, R. R. “Synthesis, Structure, and Nonlinear Optical Properties of Cross-Conjugated Perphenylated iso-Polydiacetylenes.” Chem. Eur. J., 2005, 11, 321-329.
    12. Akakpo, C., Mensah, J. K., Osei Akoto, C. Antimicrobial, Antioxidant, Anthelmintic and Anti-inflammatory bioactivities of Sabicea calycina. Int. J. Biol. Chem. Sci. 16(3): 1084-1099, June 2022. https://dx.doi.org/10.4314/ijbcs.v16i3.15
    13. Osei Akoto C, Acheampong A, Boakye YD, Naazo AA,  Adomah DH.  Anti-Inflammatory, Antioxidant, and Anthelmintic Activities of Ocimum basilicum (Sweet Basil) Fruits.  Journal of Chemistry, vol. 2020, Article ID 2153534, 9 pages, 2020;  https://doi.org/10.1155/2020/2153534.
    14. Osei Akoto C, Acheampong A, Boakye YD, Kokloku BK, Kwarteng G. In vitro anthelmintic, anti-inflammatory, antioxidant activities and FTIR analysis of Sclerocarya birrea root. Journal of Pharmacognosy and Phytochemistry 2020; 9(2): 1389-1401.
    15. Osei Akoto C, Acheampong A, Kwame O, Boateng BA. An Assessment of the Anti-Inflammatory, Antimicrobial, and Antioxidant Activities of Ficus sur Stem-Bark. Organic & Medicinal Chem IJ. 2020; 9(4): 103-111. DOI: 10.19080/OMCIJ.2020.09.555766.
    16. Osei Akoto C, Acheampong A, Tagbor PD, Bortey K. Determination of the antimicrobial and antioxidant activities of the leaf extracts of Griffonia simplicifolia. Journal of Pharmacognosy and Phytochemistry 2020; 9(2): 537-545.
    17. Osei Akoto C, Acheampong A, Boakye YD, Akwata D, Okine M. "In vitro anthelminthic, antimicrobial and antioxidant activities and FTIR analysis of extracts of Alchornea cordifolia leaves". Journal of Pharmacognosy and Phytochemistry 2019; 8(4): 2432-2442.
    18. Osei Akoto C, Acheampong A, Boakye YD, Takyi S, Garba R. "Phytochemical screening and in vitro antioxidant and antimicrobial activities of the extracts of the stem-bark of Psydrax peruviana".  Journal of Medicinal Plants Studies 2019; 7(5): 28-34.
    19. Acheampong, A., Okyem, S., Osei Akoto, C., Baah, K. D. "Antioxidant, Antimicrobial and FTIR Analysis of Methanol Root Extract of Cnestis Ferruginea and Ethanol Root Extract of Citrus Limon."  Journal of Pharmacognosy and Phytochemistry 2018; 7(4): 2938-2946.

       

      SELECTED BOOK CHAPTERS:

       

      1. Osei Akoto C. (2020) "Industrial Applications of Green Solvents in Organic and Drug Synthesis for Sustainable Development of Chemical Process and Technologies". Applications of Nanotechnology for Green Synthesis. Nanotechnology in the Life Sciences 2020; 19-40. Springer, Nature. DOI: https://doi.org/10.1007/978-3-030-44176-0_2

         

        Conferences/Seminars and Workshops 

         

        1. Osei Akoto, C “From the bench top to the market: experiments to product development.” Ghana Students’ Chemical Society (GSCS), 19TH ANNUAL NATIONAL CONFERENCE, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, March 2018, conference presentation.
        2. Osei Akoto, C “Applications of Chemistry into Drug Design and Discovery.” Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, January 2018, seminar presentation.
        3. Osei Akoto, C  “Applications of Practical Science, Research and Technology into Drug Design, Discovery, Development and Innovation for Global Benefits.” Faculty of Pharmacy, Central University College, Accra, Ghana, May 2017, seminar presentation.
        4. Osei Akoto, C  “Applications of Practical Science, Research and Technology into Drug Design, Discovery, Development and Innovation for Global Benefits.” Department of Chemistry, University of Cape Coast, Cape Coast, Ghana, May 2017, seminar presentation.
        5. Osei Akoto, C  “Applications of Practical Science, Research and Technology into Drug Design, Discovery, Development and Innovation for Global Benefits.” Faculty of Applied Science and Nursing, Garden City University College, Kumasi, Ghana, April 2017, seminar presentation.
        6. Osei Akoto, C  “Applications of Practical Science, Research and Technology into Drug Design, Discovery, Development and Innovation for Global Benefits.” 6th Ghana Science Association Research Seminar and Poster, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, April 2017, seminar presentation.
        7. Osei Akoto, C  “Applications of Practical Science, Research and Technology into Drug Design, Discovery, Development and Innovation for Global Benefits.” School of Physical and Mathematical Sciences, University of Ghana, Accra, Ghana, April 2017, seminar presentation.
        8. Osei Akoto, C  “Applications of Practical Science, Research and Technology into Drug Design, Discovery, Development and Innovation for Global Benefits.” Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, April 2017, seminar presentation.
        9. Osei Akoto, C  “Applications of Practical Science, Research and Technology into Drug Design, Discovery, Development and Innovation for Global Benefits.” Faculty of Pharmacy, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, March 2017, seminar presentation.
        10. Osei Akoto, C and Rainier, J. D. “Harnessing Glycal Epoxide Rearrangement: The Generation of the AB, EF, and IJ Rings of Adriatoxin.” Angew. Chem. Int. Ed. 2008, 47, 8055-8058.
        11. Osei Akoto, C and Rainier, J. D. “Efforts Towards the Synthesis of Adriatoxin.” Pfizer SURF/DOC Symposium, Pfizer’s Groton, CT, USA, Sept. 2007, poster presentation.
        12. Osei Akoto, C., Liu, Z., Rainier, J. D. “Methodology and Mechanistic Studies of Ring-Opening/Cross-Metathesis (ROCM) Reactions of Norbornene Derivatives.” 39th National Organic Chemistry Symposium, The University of Utah, Salt Lake City, UT, USA, June 2005, poster presentation.
        13. Zhao, Y., Slepkov, A. D., Osei Akoto, C., McDonald, R., Hegmann, F. A., Tykwinski, R. R. “Synthesis, Structure, and Nonlinear Optical Properties of Cross-Conjugated Perphenylated iso-Polydiacetylenes.” Chem. Eur. J., 2005, 11, 321-329.
        14. Osei Akoto, C., Zhao, Y., Lewis, C., Slepkov, A. D., Hegmann, F. A., Tykwinski, R. R. “Helical Twist Sense Bias in Conjugated iso-Polydiacetylene (iso-PDA) Series.” NSERC’s Nano Innovation Platform, Edmonton, AB, Canada, Dec. 2003, poster presentation.
        15. Osei Akoto, C., Zhao, Y., Lewis, C., Slepkov, A. D., Hegmann, F. A., Tykwinski, R. R. “Helical Twist Sense Bias in Conjugated iso-Polydiacetylene (iso-PDA) Series.” 1st Banff Symposium on Organic Chemistry, Banff, AB, Canada, Nov. 2003, poster presentation.
        16. Kwarteng, B. K. Kokloku, A. Acheampong, C. Osei Akoto. “Anthelminthic, Anti-Inflammatory and Antioxidant Activities of Sclerocarya birrea Root.” 8th College of Health Sciences & 12th Convention of Biomedical Research Ghana joint Scientific Conference held at the KNUST, Kumasi, Ghana. July 2019.
        17. J. Dwamena, A. Acheampong, C. Osei Akoto. In Vitro Analysis of Locally Combined Analgesics: Paracetamol, Aspirin and Caffeine on the Ghanaian Market.8th College of Health Sciences & 12th Convention of Biomedical Research Ghana joint Scientific Conference held at the KNUST, Kumasi, Ghana. July 2019.
        18. K. Bortey, P. D. Tagbor, A. Acheampong, C. Osei Akoto. Antimicrobial and Antioxidant Activities of the Leaf Extracts of Griffonia simplicifolia. 8th College of Health Sciences & 12th Convention of Biomedical Research Ghana joint Scientific Conference held at the KNUST, Kumasi, Ghana. July 2019.
        19. Takyi, R. Garba, A. Acheampong, C. Osei Akoto. Antimicrobial and Antioxidant Activities of the stem-bark of Psydrax peruviana. 8th College of Health Sciences & 12th Convention of Biomedical Research Ghana joint Scientific Conference held at the KNUST, Kumasi, Ghana. July 2019.
        20. H. Adomah, N. A. Abdulai, A. Acheampong, C. Osei Akoto. Investigating the Pharmacological Activities of Ocimum bacillicum SEEDS. 8th College of Health Sciences & 12th Convention of Biomedical Research Ghana joint Scientific Conference held at the KNUST, Kumasi, Ghana. July 2019.
        21. Bortey, P. D. Tagbor, C. Osei Akoto, A. Acheampong. Antimicrobial and Antioxidant Activities of the Leaf Extracts of Griffonia simplicifolia. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        22. J. Dwamena, C. Osei Akoto, A. Acheampong. In Vitro Analysis of Locally Combined Analgesics: Paracetamol, Aspirin and Caffeine on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        23. H. Derrick, A. A. Naazo, A. Acheampong, C. Osei Akoto. Investigating the Pharmacological Activities of Ocimum basilicum SEEDS (BASIL SEEDS). 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        24. Kwarteng, B. K. Kokloku, C. Osei Akoto, A. Acheampong. Anthelminthic, Anti-Inflammatory and Antioxidant Activities of Sclerocarya birrea Root. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        25. Garba, S. Takyi, C. Osei Akoto and A. Acheampong. Antimicrobial and Antioxidant Activities of the stem-bark of Psydrax peruviana. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        26. K. Asante, C. Osei Akoto and A. Acheampong. In Vitro Analysis of Quinine Sulfate (300 mg). 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        27. K. Coomson, C. Osei Akoto and A. Acheampong. In Vitro Drug Analysis of some Drugs Containing a Combination of Paracetamol and Diclofenac Sodium on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        28. Frimpong-Wiafe, A. Acheapong, C. Osei Akoto. In Vitro Analysis of Diazepam (10 mg) on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        29. S. Osei, C. Osei Akoto and A. Acheampong. In Vitro Drug Analysis of Penicillin V Potassium Tablets. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        30. Anning, O. Kwame, C. Osei Akoto, A. Acheampong. An Assessment of the Antimicrobial, Antioxidant and Anti-inflammatory Activities of Crude Extracts of the Stem-Bark of Ficus sur. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        31. A. Ofosu, J. K. Boafo, C. Osei Akoto, A. Acheampong. Antimicrobial, Antioxidant and Anti-inflammatory Activities of the Polar and Non-polar Extracts of the Leaves of Cercestis afzelii Schott. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        32. A. Nyarko, A. Acheampong, C. Osei Akoto. In Vitro Analysis of Combined Analgesics: Paracetamol, Ibuprofen and Caffeine on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        33. B. Ampadu, A. Acheampong, C. Osei Akoto. In Vitro Analysis of Local and Foreign Cetirizine Hydrochloride Tablets Sold on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        34. A. Awuah, A. Acheampong, C. Osei Akoto. In Vitro Analysis of Metronidazole Tablets on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Ghana. May 2019.
        35. Margaret, A. Acheampong, C. Osei Akoto. In Vitro Drug Analysis of Folic Acid Tablets on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        36. A. P. Tuffour, C. Osei Akoto, A. Acheampong. In Vitro Drug Analysis and Derivatization of Aspirin Tablets on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        37. D. Boakye, M. A. Kyei, C. Osei Akoto, and A. Acheampong. Antimicrobial, Antioxidant and anti-inflammatory Activities of the Plant Psydrax peruviana Leaves. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        38. O. Afful, A. Acheampong, C. Osei Akoto. In Vitro Analysis of Furosemide Tablets Sold on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        39. A. S. Sarpong, A. Acheampong and C. Osei Akoto. Evaluating the Quality of Different Brands of Bendroflumethiazide Tablets Sold on the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        40. Damtse, A. Acheampong, and C. Osei Akoto. In Vitro Analysis of Ciprofloxacin Hydrochloride Tablet Sampled from the Ghanaian Market. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        41. Okine, D. Akwata, A. Acheampong and C. Osei Akoto. Antimicrobial, Antioxidant and Anthelmintic Activities of Alchornea cordifolia Leaves. 8th Ghana Science Association, Research Seminar and Poster Presentations held at the KNUST, Kumasi, Ghana. May 2019.
        42. Workshop for selected Senior Members on Enhancing Entrepreneurship, Innovation and Sustainability in Higher Education in Africa (EEIS-HEA). The KNUST Office of Grants and Research (Vice Chancellor’s office), KNUST. April, 2019.
        43. KNUTS Champions for Change (C4C) Workshop for selected Senior Members on the implementation of the values of the C4C in the Department of Chemistry. Quality Assurance and Planning Unit (Vice Chancellor’s office), KNUST. 23rd – 24th October, 2018.
        44. 8th KNUST Summer School Workshop for Senior Members on Improving Quality of Higher Education through Effective Measurement and Evaluation. Quality Assurance and Planning Unit (Vice Chancellor’s office), KNUST. 20th – 24th August, 2018.
        45. Workshop for selected Senior Members on Research Grant Proposal Writing. The KNUST Office of Grants and Research (OGR) and the West Africa Built and Environment Research (WABER) Conference, KNUST. 23rd – 25th July, 2018.
        46. Workshop for selected Senior Members on Innovation and Entrepreneurship Teaching, Supervision and Research for KNUST Lecturers. The KNUST Office of Grants and Research (Vice Chancellor’s office), KNUST. 21st – 2nd May, 2018.

       

     

     

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