Dr. Clement Osei Akoto

Senior Lecturer


Dept: Chemistry
Dr. Clement Osei Akoto, Senior Research Scientist
Department of Chemistry,
KNUST - Kumasi

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Research Areas/Interests

Areas of Specialization: Organic and Bioorganic Chemistry, Pharmaceutical and Medicinal Chemistry, Spectroscopic Chemistry, Organometallic Chemis...~more


Research Areas/Interests

Areas of Specialization:

Organic and Bioorganic Chemistry, Pharmaceutical and Medicinal Chemistry, Spectroscopic Chemistry, Organometallic Chemistry, and Natural Product Chemistry.

Research Interests/Programs

  • Primarily centered on the discovery and development of new strategies for the total synthesis of a wide array of biologically important natural and synthetic products.
  • The interplay between structure-activity relationship/structure-property relationship (SAR/SPR) of biological, organic, and organometallic molecules.
  • My research undertakes extraction, isolation, purification, structure elucidation, biological screening, and synthesis of natural and synthetic products.

My research area is divided into several sub-divisions depending on the interest of my students, their capabilities and strength levels as well as the departmental or university facilities.

The area on the design, development and total synthesis of natural and synthetic products targets disease areas of anti-cancer, anti-HIV, anti-viral, microbial, pain, inflammation, anti-malaria, tuberculosis, and anti-diabetic molecules.

The medicinal and pharmaceutical chemistry field targets various disease areas mentioned above and also in collaboration and partnership with other departments particularly the pharmacy, agriculture, and medicine department, training, teaching, and researching together to benefit the university, the country, and if possible expand globally.

The field of organometallic chemistry, utilizing Pd-type coupling area of focus (Suzuki, Stille, Sonogashira and Buchwald coupling), Negishi-organozinc coupling, and other plans for the discovery, development, and synthesis of various compounds of medicinal significance.

The area of proteins, peptides and amino acid chemistry, and carbohydrate chemistry targeting various molecules of biological interest.

The reaction discovery, development, and methodology into a general synthetic schematic program of various target molecules.

The area of phytochemistry. From extraction to isolation, purification, identification, and characterization of medicinal and pharmaceutically significant plant material as well as of marine and soil natural resources.

The field of spectroscopy. Introduction and broaden students understanding in NMR, MS, FT-IR, X-RAY analysis, UV-VIS analysis, TLC Techniques, HPLC (analytical and preparative), EA, and Optical Rotation Measurements.


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