Dr. Lawrence Sheringham Borquaye

Senior Lecturer

Dept: Chemistry
Block B
Kuffuor Building
Department of Chemistry

Website: www.borquayelab.com

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Research Areas/Interests

Research in my group explores the interactions of chemical entities with biological systems and seeks to understand the ensuing effects. Rigorous benc...~more


    1. Boadi, N. O., Degbevi, M., Saah, S. A., Badu, M., Borquaye, L. S., & Kortei, N. K. (2021). Antimicrobial Properties of Metal Piperidine Dithiocarbamate Complexes against Staphylococcus aureus and Candida albicans. Scientific African, e00846.
    2. Acheampong, N. A., Akanwariwiak, W. G., Mensah, M., Fei-Baffoe, B., Offei, F., Bentil, J. A., & Borquaye, L. S. (2021). Optimization of Hydrolases Production from Cassava Peels by Trametes polyzona BKW001. Scientific African, e00835.
    3. Laryea, M. K., & Borquaye, L. S. (2021). Antimalarial, Antioxidant, and Toxicological Evaluation of Extracts of Celtis africana, Grosseria vignei, Physalis micrantha, and Stachytarpheta angustifolia. Biochemistry Research International2021.
    4. Nartey, D., Accorley, E. D., Opoku, R., Darko, G., & Borquaye, L. S. (2021). Essential Oils from Averrhoa carambola L.(Oxalidaceae): Chemical Composition, Antioxidant, Antimicrobial and Anti-biofilm Potential. Chemistry Africa, 1-12.
    5. Nartey, D., Gyesi, J. N., & Borquaye, L. S. (2021). Chemical composition and biological activities of the essential oils of Chrysophyllum albidum G. Don (African Star Apple). Biochemistry Research International2021.
    6. Ayisi, F., Mensah, C. N., & Borquaye, L. S. (2021). Antiplasmodial potential and safety evaluation of the ethanolic stem bark extract of Distemonanthus benthamianus baill.(Leguminosae). Scientific African, e00809.
    7. Mingle, C. L., Darko, G., Borquaye, L. S., Asare-Donkor, N. K., Woode, E., & Koranteng, F. (2021). Veterinary Drug Residues in Beef, Chicken, and Egg from Ghana. Chemistry Africa4(2), 339-348.
    8. Konwuruk, N., Borquaye, L. S., Darko, G., & Dodd, M. (2021). Distribution, bioaccessibility and human health risks of toxic metals in peri-urban topsoils of the Kumasi Metropolis. Scientific African11, e00701.
    9. Mingle, C. L., Darko, G., Asare-Donkor, N. K., Borquaye, L. S., & Woode, E. (2021). Patterns in protein consumption in Ghanaian cities. Scientific African11, e00684.
    10. Amo-Mensah, J., Darko, G., & Borquaye, L. S. (2020). Anti-inflammatory and antioxidant activities of the root and bark extracts of Vitex grandifolia (Verbanaceae). Scientific African10, e00586.
    11. Akanchise, T., Boakye, S., Borquaye, L. S., Dodd, M., & Darko, G. (2020). Distribution of heavy metals in soils from abandoned dump sites in Kumasi, Ghana. Scientific African10, e00614.
    12. Afu, G., Laryea, M. K., & Borquaye, L. S. (2020). Biological efficacy and toxicological evaluation of ethanolic extract of Cassia nodosa Buch.-ham.(leguminosae). Journal of Chemistry2020.
    13. Borquaye, L.S., Gasu, E.N., Ampomah, G.B., Kyei, L.K., Amarh, M.A., Mensah, C.N., Nartey, D., Commodore, M., Adomako, A.K., Acheampong, P. and Mensah, J.O., 2020. Alkaloids from Cryptolepis sanguinolenta as potential inhibitors of SARS-CoV-2 viral proteins: an in silico study. BioMed Research International2020.
    14. Darko, G., Adjei, S., Nkansah, M.A., Borquaye, L.S., Boakye, K.O. and Dodd, M., 2020. Accumulation and bioaccessibility of toxic metals in root tubers and soils from gold mining and farming communities in the Ashanti region of Ghana. International Journal of Environmental Health Research, pp.1-11.
    15. Borquaye, L.S., Laryea, M.K., Gasu, E.N., Boateng, M.A., Baffour, P.K., Kyeremateng, A. and Doh, G., 2020. Anti-inflammatory and antioxidant activities of extracts of Reissantia indica, Cissus cornifolia and Grosseria vignei. Cogent Biology, 6(1), p.1785755.
    16. Borquaye, L.S., Doetse, M.S., Baah, S.O. and Mensah, J.A., (2020). Anti-inflammatory and anti-oxidant activities of ethanolic extracts of Tamarindus indica L.(Fabaceae). Cogent Chemistry, 6(1), p.1743403.
    17. Ofori – Baah, S. & Borquaye, L. S. (2019) Ethanolic leaf extract from Strophanthus gratus (Hook.) Franch. (Apocynaceae) exhibits anti-inflammatory and antioxidant activities, Cogent Biology, 5:1, DOI: 10.1080/23312025.2019.1710431
    18. Gyesi, J.N., Opoku, R. and Borquaye, L.S., (2019) Chemical Composition, Total Phenolic Content, and Antioxidant Activities of the Essential Oils of the Leaves and Fruit Pulp of Annona muricata L.(Soursop) from Ghana. Biochemistry Research International, 2019.
    19. Laryea, M.K. and Borquaye, L.S., (2019) Antimalarial Efficacy and Toxicological Assessment of Extracts of Some Ghanaian Medicinal Plants. Journal of Parasitology Research, 2019.
    20. Gasu, E.N., Ahor, H.S. and Borquaye, L.S., 2019. Peptide Mix from Olivancillaria hiatula Interferes with Cell-to-Cell Communication in Pseudomonas aeruginosa. BioMed Research International, 2019.
    21. Borquaye, L.S., Ekuadzi, E., Darko, G., Ahor, H.S., Nsiah, S.T., Lartey, J.A., Mutala, A.H., Boamah, V.E. and Woode, E., (2019) Occurrence of Antibiotics and Antibiotic-Resistant Bacteria in Landfill Sites in Kumasi, Ghana. Journal of Chemistry, 2019.
    22. Gasu, E. N., Ahor, H. S., & Borquaye, L. S. (2018). Peptide Extract from Olivancillaria hiatula Exhibits Broad-Spectrum Antibacterial Activity. BioMed Research International, 2018.
    23. Forkuoh, F., Boadi, N. O., Borquaye, L. S., & Afful, S. (2018). Risk of Human Dietary Exposure to Organochlorine Pesticide Residues in Fruits from Ghana. Scientific Reports, 8(1), 16686.
    24. Boadi, N. O., Borquaye, L. S., Darko, G., Wemegah, D. D., Agorsor, D., & Akrofi, R. (2018). Assessment of the quality of the Owabi reservoir and its tributaries. Cogent Food & Agriculture, 4(1), 1-15.
    25. Bolor, V. K., Boadi, N. O., Borquaye, L. S., & Afful, S. (2018). Human Risk Assessment of Organochlorine Pesticide Residues in Vegetables from Kumasi, Ghana. Journal of Chemistry, 2018.
    26. Borquaye, Lawrence Sheringham, Edmund Ekuadzi, Yvonne Esseku, Hubert Senanu Ahor, Sarah T Nsiah, Jemima A Lartey, Abdul H Murtala, Godfred Darko, and Eric Woode. (2018). “Disposal of Unused and Expired Medicines in Ghana.” West African Journal of Pharmacy 29 (1): 84–92
    27. Darko, G., Addai-Tabi, J., Adjaloo, M. K., and Borquaye, L. S., 2017, Pesticide residues in honey from the major honey producing forest belts in Ghana. Journal of Environmental and Public Health, 2017, Article ID 7957431
    28. Borquaye, L.S., Darko, G., Laryea, M.K., Roberts, V., Boateng, R. and Gasu, E.N., 2017. Anti-inflammatory activities of extracts from Oliva sp., Patella rustica and Littorina littorea collected from Ghana’s coastal shorelines. Cogent Biology, p.1364063.
    29. Borquaye, L.S., Darko, G., Laryea, M.K., Gasu, E.N., Amponsah, N.A.A. and Appiah, E.N., 2017. Nutritional and anti-nutrient profiles of some Ghanaian spices. Cogent Food & Agriculture, 3(1), p.1348185.
    30. Darko, G., Dodd, M., Nkansah, M. A., Aduse-Poku, Y., Ansah, E., Dotse Wemegah, D. and Borquaye, L. S., 2017. Distribution and ecological risks of toxic metals in the topsoils in the Kumasi metropolis, Ghana. Cogent Environmental Science, 3(1), 1354965.
    31. Darko, G., Borquaye, L. S., Acheampong, A., & Oppong, K., 2017, Veterinary antibiotics in dairy products from Kumasi, Ghana. Cogent Chemistry, 3(1), p1343636
    32. Nkansah, M.A., Hayford, S.T., Borquaye, L.S. and Ephraim, J.H., 2016. Heavy metal contents of some medicinal herbs from Kumasi, Ghana. Cogent Environmental Science, 2(1), p.1234660.
    33. Borquaye, L.S., Ocansey, E. and Semenya, J., 2016. Inhibitory Effect of Selected Ghanaian Clay Leachates on Some Pathogenic Microbes. American Journal of Microbiology and Immunology, 1(1), pp.1-5.
    34. Borquaye, L.S., Darko, G., Oklu, N., Anson-Yevu, C. and Ababio, A., 2016. Antimicrobial and antioxidant activities of ethyl acetate and methanol extracts of Littorina littorea and Galatea paradoxa. Cogent Chemistry, 2(1), p.1161865.
    35. Borquaye, L.S., Darko, G., Ocansey, E. and Ankomah, E., 2015. Antimicrobial and antioxidant properties of the crude peptide extracts of Galatea paradoxa and Patella rustica. SpringerPlus, 4(1), p.500.
    36. Akoto, O., Borquaye, L.S., Howard, A.S. and Konwuruk, N., 2015. Nutritional and Mineral Composition of the Fruits of Solanum torvum from Ghana. International Journal of Chemical and Biomolecular Science, 4, pp.222-226.
    37. Acheampong, A., Borquaye, L.S., Acquaah, S.O., Osei-Owusu, J. and Tuani, G.K., 2015. Antimicrobial Activities of Some Leaves and Fruit Peels Hydrosols. International Journal of Chemical and Biomolecular Science, 1, pp.158-162.
    38. Lin, T-Y, Borketey, L.S., Prasad, G., Waters, S.A., Schnarr, N.A., ‘Sequence, Cloning, and Analysis of the Fluvirucin B1 Polyketide Synthase from Actinomadura vulgaris’, ACS Synth. Biol., 2013, 2(11), 635-642
    39. Prasad, G., Borketey, L.S., Lin, T., Schnarr, N.A., ‘A Mechanism-Based Fluorescence Transfer Assay for Examining Ketosynthase Selectivity’. Org. Biomol. Chem, 2012, 10, 6717-6723
    40. Prasad, G., Amoroso, J. W., Borketey, L. S., Schnarr, N. A., ‘N-Activated β-Lactams as Versatile Reagents for Acyl Carrier Protein Labeling’. Org. Biomol. Chem, 2012, 10, 1992-2002
    41. Amoroso, J. W., Borketey, L. S., Prasad, G., and Schnarr, N. A., ‘Direct Acylation of Carrier Proteins with Functionalized β-Lactones’. Org. Lett., 2010, 12, 2330-2333

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