Through Emmanuel Antwi's empathy teaching, he has theoretically and practically groomed and seen to the graduation of several students on all levels in his Department. He has taught Still Life, Museum Studies, Seminar, Experimental Painting, Figure Painting, Elements and Principles of Design, Thematic Figure Painting and Thematic Composition. Over the years, he has had a pleasant teaching career bolstered with sensitivity towards student needs.

He has held a number of solo and group exhibitions. Having works in both private and public collections. In 2005, over twenty works of his were exhibited at the newly built structure of the Oncology Department of the Komfo Anokye teaching Hospital (KATH) Kumasi, was opened by the then President of Ghana, His Excellency John Agyekum Kuffour. Which collection remain on permanent display, being periodically maintained by the artist. In the same year, the management of SKYY FM of Takoradi assigned him to design an acoustic-aesthetic interior for their TV and radio studios. This breakthrough was inspired by His foam-rubber relief paintings that had been earlier explored during his MFA programme. Through his ingenious studio practice, the portrait of Nana Ama Dapaah Kuffour (mother of Ex-President John Agyekum and Addo Kuffour), originally painted by the artist Leroy Mtchell (Paa Kwame), but had terribly deteriorated over time, was excellently restored by Emmanuel Antwi.