Dr. Opoku specializes in the computational and experimental design of novel two-dimensional (2D) materials for various advanced applications, including:

• Water splitting (for hydrogen production)
• Photodegradation of organic pollutants (environmental remediation)
• Molecular and gas sensors (for detecting harmful substances)
• Optoelectronic devices (e.g., LEDs, photodetectors)
• Thermoelectric materials (for energy harvesting)
• Photovoltaic cells (solar energy conversion)

His work contributes to renewable energy, environmental sustainability, and nanotechnology, making him a key researcher in materials chemistry within Ghana and beyond.

He has published more than 90 publications appearing in high-impact peer-reviewed journals like the New Journal of Chemistry, Scientific Reports, Journal of Cleaner Production, Applied Catalysis B: Environmental, Chemical Engineering Journal, and ACS Applied Materials and Interfaces, to name but a few.