Prof. Marcel Tunkumgnen Bayor

Professor


Dept: Pharmaceutics
Department of Pharmaceutics
KNUST, Kumasi
Ghana

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Research Areas/Interests

GENERAL RESEARCH INTEREST:  Scientific investigations into plant medicines with especially, anticancer, antimalarial and or antimicrobial activity ...~more

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Research Projects (Current and Past)

The effects of co-administration of herbal formulations such as anticancer, antimalarial and antimicrobial products, and orthodox medicines, especially antibiotics (2009 – 2010).

Investigations into the extent of heavy metal contamination of Ghanaian medicinal plants used in formulations for the treatment of malaria, infections and cancers (2009 – 2011).

The biological testing of the extract and compounds obtained from Croton membranaceus root for anticancer, antiplasmodial and antimicrobial activities (2009 – 2011).

Investigations into the quality, accuracy and use of household spoons as well as enclosed dosing devices for the administration of liquid medications in Ghana (2009 – 2010).

The formulation of the extracts and isolates of Croton membranaceus root into suitable pharmaceutical formulations and the determination of their effectiveness and drug release properties (2010 – 2012).

The formulation of various herbal materials and remedies into appropriate and suitable dosage forms (such as; suppositories, pessaries, ointments, creams, gels and paste) for industry and commerce (2010 and still on-going).

Investigations into the wound healing potential of antimicrobial plant agents, including; Alchornea cordifolia, Spathodea campanulata and Xylopia aethiopica (2010 – 2013).

Investigations into the use of adsorbents in the conversion of liquid herbal remedies into powders for use in solid dosage formulations (2010 – 2011).

The use of the capsule as a convenient dosage form for herbal remedies, including; Croton membranaceus root, Bridelia ferruginea Leaf and Canthium glabriflorum Stem Bark, extracts (2010 and still on-going).

The antimalarial properties of Ghanaian medicinal plants - the phytochemical and chromatographic analysis of their extracts and the isolation and characterization of compounds there-in (2010 and still on-going).

The incidence of triple negative breast cancer (TNBC) in Ghana – the case of Komfo Anokye Teaching Hospital (KATH) (2011).

The influence of women’s reproductive health, diet and nutrition on breast cancer risk in Ghana (2011 – 2012).

Investigations into the suitability and use of starches from sweet potato varieties in Ghana as excipients in solid pharmaceutical dosage forms (2011 – 2013).

The pharmaceutical applications of the fruit pulp of Parkia biglobosa (Leguminosae) (i.e. the African locust bean) (2011 - 2013).

Investigations into the role and activities of Alchornea cordifolia (Euphorbiaceae) (a perennial shrub in Ghana), as the main component in antimicrobial and antiasthmatic herbal formulations in Ghana (2002 - 2003).

Standardization of Alchornea cordifolia formulations for external use (i.e. creams and ointments) as well as for oral administration (i.e. mixtures, tablets and capsules) (2003 - 2004).

The characterization of microemulsions formulated with commercial non-ionic surfactants (2004).

Comparative studies of microemulsions and micellar solutions of non-ionic surfactants as vehicles for improved drug solubilisation and delivery (2004).

Investigations into the haemolytic activity of micellar solutions of non-ionic surfactants and their corresponding microemulsions as potential vehicles for parenteral drug administration (2004 - 2005).

The selection of Ghanaian medicinal plants with folkloric or traditional uses in anticancer formulations (i.e. as anticancer agents), and scientific investigations into the possible anticancer activity of these plant agents (2005).

The phytochemical and chromatographic analysis of Croton membranaceus (Euphorbiaceae), as a potent anticancer agent used in formulations at the Centre for Scientific Research into Plant Medicine (CSRPM) Mampong Akwapem, for the treatment and management of prostatic hypertrophy and related cancers (2006 - 2007).

The biological testing of the extract and compounds obtained from Croton membranaceus root for anticancer, antiplasmodial and antimicrobial activities (2007 - 2008).


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