Publications
PEER REVIEWED JOURNALS
1. Batsa Debrah L, Klarmann-Schulz U, Osei-Mensah J, Dubben B, Fischer K, Mubarik Y, Ayisi-Boateng NK, Ricchiuto A, Fimmers R, Konadu P, Nadal J, Gruetzmacher B, Weil G, Kazura JW, King CL, Debrah AY, Hoerauf A. (2019). Comparison of repeated doses of ivermectin versus ivermectin plus albendazole for treatment of onchocerciasis - a randomized open-label clinical trial. Clin Infect Dis XX:XXX: 1-11
2. Batsa Debrah L, Phillips RO, Pfarr K, Klarmann-Schulz U, Opoku VS, Nausch N, Owusu W, Mubarik Y, Sander AL, Lämmer C, Ritter M, Layland LE, Jacobsen M, Debrah AY, Hoerauf A. (2019). The Efficacy of Doxycycline Treatment on Mansonella perstans Infection: An Open-Label, Randomized Trial in Ghana. Am J Trop Med Hyg. 101 (1): 84-92.
3. Ritter M, Osei-Mensah J, Debrah LB, Kwarteng A, Mubarik Y, Debrah AY, Pfarr K, Hoerauf A, Layland LE (2019). Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment. PLoS Negl Trop Dis. 13(5):e0007436.
4. Wanji S, Tayong DB, Ebai R, Opoku V, Kien CA, Ndongmo WPC, Njouendou AJ, Ghani RN, Ritter M, Debrah YA, Layland LE, Enyong PA, Hoerauf A (2019). Update on the biology and ecology of Culicoidesspecies in the South-West Region of Cameroon with implications on the transmission of Mansonella perstans. Parasit Vectors. 12(1):166.
5. Lagatie O, Verheyen A, Nijs E, Batsa Debrah L, Debrah YA, Stuyver LJ (2019). Performance evaluation of 3 serodiagnostic peptide epitopes and the derived multi-epitope peptide OvNMP-48 for detection of Onchocercavolvulus infection. Parasitol Res. 2019 May 14. doi: 10.1007/s00436-019-06345-3.
6. Lagatie O, Verheyen A, Van Dorst B, Batsa Debrah L, Debrah A, Stuyver LJ. (2018). Linear epitopes in Onchocerca volvulus vaccine candidate proteins and excretory-secretory proteins. Parasite Immunol. 40(11)
7. Lagatie O, Verheyen A, Nijs E, Van Dorst B, Batsa Debrah L, Debrah A, Supali T, Sartono E, Stuyver LJ (2018). Evaluation of the Diagnostic Performance of Onchocerca volvulus Linear Epitopes in a Peptide Enzyme-Linked Immunosorbent Assay. Am J Trop Med Hyg. doi: 10.4269/ajtmh.17-0756.
8. Debrah LB, Albers A, Debrah AY, Brockschmidt FF, Becker T, Herold C, Hofmann A, Osei-Mensah J, Mubarik Y, Fröhlich H, Hoerauf A, Pfarr K (2017). Single nucleotide polymorphisms in the angiogenic and lymphangiogenic pathways are associated with lymphedema caused by Wuchereria bancrofti. Hum Genomics. 11(1):26. doi: 10.1186/s40246-017-0121-7
9. Prodjinotho UF, von Horn C, Debrah AY, Batsa Debrah L, Albers A, Layland LE, Hoerauf A, Adjobimey T. (2017). Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes. PLoS Negl Trop Dis. 11(7):e0005777.
10. Globisch D, Eubanks LM, Shirey RJ, Pfarr KM, Wanji S, Debrah AY, Hoerauf A, Janda KD. (2017). Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG). Bioorg Med Chem Lett. 27(15):3436-3440.
11. Lagatie O, Batsa Debrah L, Debrah A, Stuyver LJ. (2017). Plasma-derived parasitic microRNAs have insufficient concentrations to be used as diagnostic biomarker for detection of Onchocerca volvulus infection or treatment monitoring using LNA-based RT-qPCR.Parasitol Res. 16(3): 1013-1022
12. Nausch N, Antwi-Berko D, Mubarik Y, Abass KM, Owusu W, Owusu-Dabo E, Debrah LB, Debrah AY, Jacobsen M, Phillips RO. (2017). Analysis of Mycobacterium ulcerans-specific T- cell cytokines for diagnosis of Buruli ulcer disease and as potential indicator for disease progression. PLoS Negl Trop Dis. 11(2):e0005415.
13. Lagatie O, Merino M, Debrah LB, Debrah AY and Stuyver LJ (2016) An Isothermal DNA Amplification Method for Detection of Onchocerca Volvulus Infection in Skin Biopsies. Parasites & Vectors 9:624
14. Debrah LB, Nausch N, Opoku VS, Owusu W, Mubarik Y, Berko DA, Wanji S, Layland LE, Hoerauf A, Jacobsen M, Debrah AY, Phillips RO. (2017) Epidemiology of Mansonella perstans in the middle belt of Ghana. Parasit Vectors. 10(1):15.
15. Klarmann-Schulz U, Specht S, Debrah AY, Batsa L, Ayisi-Boateng NK, Osei-Mensah J, Mubarik Y, Konadu P, Ricchiuto A, Fimmers R, Arriens S, Dubben B, Ford L, Taylor M, Hoerauf A. (2017) Comparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot Trial. PLoS Negl Trop Dis. 11(1):e0005156.
16. Lagatie O, Njumbe Ediage E, Batsa Debrah L, Diels L, Nolten C, Vinken P, Debrah A, Dillen L, Silber S, Stuyver LJ. (2016). Evaluation of the diagnostic potential of urinary N-Acetyltyramine-O,β-glucuronide (NATOG) as diagnostic biomarker for Onchocerca volvulus infection. Parasit Vectors. 239 (1):302.
17. Stanton MC, Best A, Cliffe M, Kelly-Hope L, Biritwum NK, Batsa L, Debrah A. (2016). Situational analysis of lymphatic filariasis morbidity in Ahanta West District of Ghana. Trop Med Int Health. 21:236-44
18. Stanton MC, Mkwanda SZ, Debrah AY, Batsa L, Biritwum NK, Hoerauf A, Cliffe M, Best A, Molineux A, Kelly-Hope LA (2015). Developing a community-led SMS reporting tool for the rapid assessment of lymphatic filariasis morbidity burden: case studies from Malawi and Ghana BMC Infect Dis. 15:214
19. Debrah AY, Specht S, Batsa L, Klarmann U, Mand S, Kwarteng A, Osei-Atweneboana M, Boakye D, Adjei O and Hoerauf A. (2015) Doxycycline treatment shows a strong embryostatic effect and clearance of persistent microfilariae in the skin of onchocerciasis patients in whom repeated ivermectin treatment had failed to clear microfilaridermia. Journal of clinical Infectious Diseases 61:517-26
20. Arndts K, Klarmann-Schulz U, Batsa L, Debrah AY, Epp C, Fimmers R, Specht S, Layland LE, Hoerauf A (2015). Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals. Parasit & Vectors 184. doi: 10.1186/s13071-015-0786-5
21. Klarmann-Schulz U, Arndts K, Batsa L, Debrah A, Epp C, Fimmers R, Specht S, Layland RE, Hoerauf A. (2015). Ivermectin treatment is crucial for Plasmodium-specific Th17 mmune responses in Onchocerca volvulus-infected individuals. Parasit Vectors 184. doi: 10.1186/s13071-015-0786-5
22. Quintana JF, Makepeace BL, Babayan SA, Ivens A, Pfarr KM, Blaxter M, Debrah A, Wanji S, Ngangyung HF, Bah GS, Tanya VN, Taylor DW, Hoerauf A, Buck AH (2015). Extracellular Onchocerca -derived small RNAs in host nodules and blood. Parasit Vectors. 8(1):58. doi: 10.1186/s13071-015-0656-1.
23. Garms R, Badu K, Owusu-Dabo E, Baffour-Awuah S, Adjei O, Debrah AY, Nagel M, Biritwum NK, Gankpala L, Post RJ, Kruppa TF (2015). Assessments of the transmission of Onchocerca volvulus by Simulium sanctipauli in the Upper Denkyira District, Ghana, and the intermittent disappearance of the vector. Parasitol Res. 114:1129–1137
24. Katawa G, Layland LE, Debrah AY, von Horn C, Batsa L, Kwarteng A, Arriens S, W Taylor D, Specht S, Hoerauf A, Adjobimey T. (2015). Hyperreactive Onchocerciasis is Characterized by a Combination of Th17-Th2 Immune Responses and Reduced Regulatory T Cells. PLoS Negl Trop Dis. 8;9(1):e3414. doi: 10.1371/journal.pntd.0003414.
25. Arndts K, Specht S, Debrah AY, Tamarozzi F, Klarmann Schulz U, Mand S, Batsa L, Kwarteng A, Taylor M, Adjei O, Martin C, Layland LE, Hoerauf A. (2014). Immunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levels. PLoS Negl Trop Dis. 20;8(2):e2679. doi: 10.1371/journal.pntd.0002679.
26. Richard O. Phillips, Michael Frimpong, Fred S. Sarfo, Birte Kretschmer, Marcus Beissner, Alexander Debrah, Yaw Ampem-Amoako, Kabiru M. Abass, William Thompson, Mabel Sarpong Duah, Justice Abotsi, Ohene Adjei, Bernhard Fleischer, Gisela Bretzel, Mark Wansbrough-Jones, and Marc Jacobsen (2014). Infection with Mansonella perstans Nematodes in Buruli Ulcer Patients, Ghana. Emerg Infect Dis. 20:1-7
27. Gyasi SF, Awuah E, Koffour GA, Sampson DK, Debrah AY (2014). Comparative analysis of environmental arsenic and other heavy metals in 2 Buruli Ulcer endemic districts in the Ashanti Region, Ghana. JENRM I: 56-62
28. Specht S, Debrah AY, Klamann U. Mand S, Hoerauf A and Pfarr K. (2013). Chemotherapy of filariasis- Established strategies and new developments. GMS infectious diseases vol 1 ISSN 2195-8831
29. Gyasi S, Awuah E, Larbi JA, Koffuor GA, Debrah A, Awuah-Boateng N, Owusu-Afriyie O. (2013). Susceptibility of Arsenic-Exposed ICR Mice to Buruli Ulcer Development. Pharmacologia 4: 254-264.
30. Mand S, Debrah AY, Klarmann U, Batsa L, Marfo-Debrekyei Y, Kwarteng A, Specht S, Belda-Domene A, Fimmers R, Taylor M, Adjei O, Hoerauf A (2012). Doxycycline Improves Filarial Lymphedema Independent of Active Filarial Infection: A Randomized Controlled Trial. Clin Infect Dis. 55: 621-630
31. Arndts, K., Deininger, S., Specht, S., Klarmann, U., Mand, S., Adjobimey, T., Debrah, A.Y., Batsa, L., Kwarteng, A., Epp, C., Taylor, M., Adjei, O., Layland, L.E., Hoerauf, A. (2012). Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti. PLoS Negl Trop Dis.6(4):e1611. doi: 10.1371/
32. Debrah, A.Y., Batsa, L., Albers, A., Mand, S., Toliat, M.R., Nürnberg, P., Adjei, O., Hoerauf, A., and Pfarr, K. (2011). Transforming Growth Factor-β 1 variant Leu10Pro is associated with both lack of Microfilariae and differential Microfilarial loads in the blood of people infected with lymphatic filariasis. Hum Immunol 72:1143-8
33. Debrah, A.Y., Mand, S., Marfo-Debrekyei, Y., Batsa, L., Albers, A., Specht, S., Klarmann, U., Pfarr, K., Adjei, O., and Hoerauf, A. (2011). Macrofilaricidal Activity in Wuchereria bancrofti after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline. J Parasitol Res 17:977-85.
34. Hoerauf, A., Pfarr, K., Mand, S., Debrah, A.Y., and Specht, S. (2011). Filariasis in Africa-treatment challenges and prospects. Clin Microbiol Infect 17, 977-985.
35. Mand S, Debrah AY, Klarmann U, Mante S, Kwarteng A, Batsa L, Marfo-Debrekyei Y, Adjei O, Hoerauf A (2010). The role of ultrasonography in the differentiation of the various types of filaricele due to bancroftian filariasis. Acta Trop. 20 Suppl 1:S23-32
36. Brattig N, Hoerauf A, Fischer P, Liebau E, Bandi C, Debrah AY, Buettner M, Buettner DW (2009). Immunohistological studies on neoplasms of female and male Onchocerca volvulus: filarial origin and role of Wolbachia endobacteria. Parasitology 137: 1-14
37. Debrah AY, Mand S, Marfo-Debrekyei Y, Batsa L, Pfarr K, Lawson B, Taylor M, Adjei O, Hoerauf A (2009). Reduction in levels of plasma vascular endothelial growth factor-A and improvement in hydrocele patients by targeting endosymbiotic Wolbachia sp. in Wuchereria bancrofti with doxycycline. Am J Trop Med Hyg. 80:956-963.
38. Attout T, Hoerauf A, Denece´ G, Debrah AY, Marfo-Debrekyei Y, Boussinesq M, Wanji S, Martinez V, Mand S, Adjei O, Bain O, Specht S., Martin C (2009). Lymphatic Vascularisation and Involvement of Lyve-1+ Macrophages in the Human Onchocerca Nodule. PLoS ONE 4(12): e8234. doi:10.1371/journal.pone.0008234
39. Specht S, Hoerauf A, Adjei O, Debrah A, Büttner DW (2009). Newly acquired Onchocerca volvulus filariae after doxycycline treatment. Parasitol Res. Res.103:1303-1309
40. Mand S, Pfarr K, Sahoo PK, Satapathy AK, Specht S, Klarmann U, Debrah AY, Ravindran B, and Hoerauf A (2009). Macrofilaricidal activity and amelioration of lymphatic pathology in bancroftian filariasis after 3 weeks doxycycline followed by single-dose diethylcarbamazine. Am J Trop Med Hyg. 2009 81:702-11
41. Pfarr K, Debrah AY, Specht S and Hoerauf A (2009). Filariasis and lymphoedema (Review). Parasite Immunol. 2009 11 :664-72.
42. Taylor MJ, Awadzi K, Basanez MG, Biritwum N, Boakye D, Boatin B, Bockarie M, Churcher TS, Debrah A, Edwards G, Hoerauf A, Mand S, Matthews G, Osei-Atweneboana M, Prichard RK, Wanji S, Adjei O. (2009). Onchocerciasis control: vision for the future from a Ghanian perspective. Parasit &Vectors. 21:1:7.
43. Hoerauf A, Specht S, Marfo-Debrekyei Y, Büttner M, Debrah AY, Mand S, Batsa L, Brattig N, Konadu P, Bandi C, Fimmers R, Adjei O, Büttner DW (2009). Efficacy of 5-week doxycycline treatment on adult Onchocerca volvulus. Parasitol Res.104:437-447.
44. Specht S, Mand S, Marfo-Debrekyei Y, Debrah AY, Konadu P, Adjei O, Büttner DW, Hoerauf A (2008). Efficacy of 2- and 4-week rifampicin treatment on the Wolbachia of Onchocerca volvulus. Parasitol Res.103:1303-1309.
45. Hoerauf A, Marfo-Debrekyei Y, Büttner M, Debrah AY, Konadu P, Mand S, Adjei O, Büttner DW. (2008). Effect of six weeks azithromycin treatment on the Wolbachia endobacteria of Onchocerca volvulus. Parasitol Res.103:279-86
46. Hoerauf A, Specht S, Büttner M, Pfarr K, Mand S, Fimmers R, Marfo-Debrekyei Y, Konadu P, Debrah AY, Bandi B, Brattig N, Albers A, Larbi J, Batsa L, Adjei O, Büttner DW. (2007). Wolbachia endobacteria depletion by doxycycline as antifilarial therapy is macrofilaridical in onchocerciasis. Med Microbiol Immunol 196:10.1007/s00430-00007-00062-00431
47. Debrah, AY., Mand, S., Toliat, M. R., Marfo-Debrekyei, Y., Batsa, L., Nürnberg, P., Lawson, B., Adjei, O., Hoerauf, A. & Pfarr, K. (2007). Plasma vascular endothelial growth factor-A (VEGF-A) and VEGF-A gene polymorphism are associated with hydrocele development in lymphatic filariasis. Am J Trop Med Hyg 77: 601-608
48. Debrah, AY., Mand, S., Marfo-Debrekyei, Y., Batsa, L., Pfarr, K., Büttner, M., Adjei, O., Büttner, D. & Hoerauf, A. (2007). Macrofilaricidal activity after 4 weeks doxycycline treatment of Wuchereria bancrofti. Trop Med Int Health, 12:1433-1441
49. Debrah, AY., Mand, S., Marfo-Debrekyei, Y., Larbi, J., Adjei, O. & Hoerauf, A. (2006). Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin. Filaria J 5, 1.
50. Debrah, AY., Mand, S., Specht, S., Marfo-Debrekyei, Y., Batsa, L., Pfarr, K., Larbi, J., Lawson, B., Taylor, M., Adjei, O. & Hoerauf, A. (2006). Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis. PLoS Pathog 2, e92.
51. Turner, J. D., Mand, S., Debrah, AY., Muehlfeld, J., Pfarr, K., McGarry, H. F., Adjei, O., Taylor, M. J. & Hoerauf, A. (2006). A randomized, double-blind clinical trial of a 3-week course of doxycycline plus albendazole and ivermectin for the treatment of Wuchereria bancrofti infection. Clin Infect Dis 42, 1081-1089.
52. Mand, S., Marfo-Debrekyei, Y., Debrah, A., Buettner, M., Batsa, L., Pfarr, K., Adjei, O. & Hoerauf, A. (2005). Frequent detection of worm movements in onchocercal nodules by ultrasonography. Filaria J 4, 1.
53. Mand, S., Debrah, AY., Batsa, L., Adjei, O. & Hoerauf, A. (2004). Reliable and frequent detection of adult Wuchereria bancrofti in Ghanaian women by ultrasonography. Trop Med Int Health 9, 1111-1114.
54. Hoerauf, A., Mand, S., Fischer, K., Kruppa, T., Marfo-Debrekyei, Y., Debrah, A. Y., Pfarr, K. M., Adjei, O. & Buttner, D. W. (2003). Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production. Med Microbiol Immunol 192, 211-216.
55. Hoerauf A., Marfo-Debrekyei Y, Adjei O, Debrah A, Fischer K, and Mand S (2003). Loss of worm nests after treatment of Wuchereria bancrofti with doxycycline for six weeks suggests a macrofilaricidal effect. Am. J. Trop. Med. Hyg. 69:249.
ABSTRACTS PRESENTATION AT CONFERENCES
Kroidl I, Feichtner A, Horn S, Mwingira U, Ngenya A, Chotta G, Klarmann-Schulz U, Kuehlwein J, Hoerauf A, Osei-Mensah J, Debrah LB, Debrah AY (2019). Immune activation in patients with filarial lymphedema before and after treatment with doxycycline. 68th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), National Harbor, MA, USA, November 2019 (Poster presentation- Abstract No. 528).
Debrah LB, Osei-Mensah J, Mubarik Y, Mohammed A, Agbenyega O, Ayisi-Boateng NK, Kuehlwein JM, Klarmann-Schulz U, Hoerauf A, Debrah AY (2019). Lymphatic filariasis pathology and acute Dermatolymphangioadenitis (ADLA) attacks using a mobile phone-based tool by community health volunteers in Ghana. 68th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), National Harbor, MA, USA, November 2019 (Oral presentation- Abstract No. 1283).
Gyamfi PA, Debrah AY, Osei-Mensah J, Opoku SV, Adu-Mensah D, Mubarik Y, Horeauf A, Debrah LB (2019). Impact of 15 Years of Mass Drug Administration on Lymphatic Filariasis Control Efforts in the Kassena Nankana East Municipal. The 8th College of Health Sciences and 12th Convention of Biomedical Research Kumasi, Ghana, July 2019 (Oral presentation- Abstract No. 4).
Fordjour FA, Debrah LB, Osei-Mensah J, Mubarik Y, Gyamfi PA, Debrah AY (2019). Assessing the Involvement of Nuclear Kappa Light Chain Enhancer of Activated B cell Inhibitor-Alpha in Filarial Lymphedema Development. The 8th College of Health Sciences and 12th Convention of Biomedical Research Kumasi, Ghana, July 2019 (Oral presentation- Abstract No. 14).
Mubarik Y, Debrah LB, Osei-Mensah J, 1, Fordjour FA, Debrah AY (2019). Microfilaridermia Assessment of the Efficacy of Ivermectin Alone and Ivermectin
Plus Albendazole against Onchocerciasis. The 8th College of Health Sciences and 12th Convention of Biomedical Research Kumasi, Ghana, July 2019 (Poster presentation- Abstract No. P012).
Batsa-Debrah L, Specht S, Klarmann-Schulz U, Debrah AY, Osei-Mensah J, Dubben B, Mand S, Mubarik Y, Ricchiuto A, Fimmers R, Johnston K, Taylor M, Hoerauf A (2017). Doxycycline for the treatment of onchocerciasis: A daily dose of 100 mg for 6 weeks shows Reduction of fertile female onchocerca volvulus Worms equivalent to 200 mg/d. 66th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2017 (Oral presentation- Abstract No. 531).
Klarmann-Schulz U, Batsa-Debrah L, Osei-Mensah J, Dubben B, Fischer K, Mubarik Y, Ricchiuto A, Fimmers R, Weil GJ, Kazura JW, King CL, Debrah AY, Hoerauf A (2017). The addition of albendazole to ivermectin does not reduce female worm fertility in onchocerciasis. 66th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2017 (Oral presentation- Abstract No. 533).
Nausch N, Antwi-Berko D, Mubarik Y, Kabiru MA, Owusu W, Owusu-Dabo E, Debrah LB, Debrah AY,Jacobsen M, Phillips RO (2017). Biomarkers and immune modulation in Buruli Ulcer disease. 66th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2017 (Oral presentation- Abstract No. 752).
Lagatie O, Verheyen A, Nijs N, Van Dorst B, Batsa Debrah L, Debrah A, Stuyver, LJ (2016). Immunoreactivity of an Onchocerca volvulus linear epitope in individuals from different Regions in Ghana. 65th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2016 (Oral presentation- Abstract No. 496).
Osei-Mensah J, Ritter M, Batsa-Debrah L, Albers A, Mubarik Y, Layland L, Pfarr K, Hoerauf A, Debrah A (2016). Toll-like receptor 2 expression on immune cells is elevated in cured asymptomatic individuals in lymphatic filariasis. 65th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, October 2016 (Oral presentation- Abstract No. 598).
Osei-Mensah J, Batsa Debrah L, Albers A, Lust L, Brockschmidt F, Becker T, Herold C, Mubarik Y, Fröhlich H, Pfarr K, Hoerauf A and Debrah A. Single nucleotide polymorphisms in angiogenic and inflammation pathway genes predispose infected hosts to having patent or latent lymphatic filariasis. 64th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, October 2015 (Poster presentation- Abstract No. 1708).
Weier C, Albers A, Batsa-Debrah L, Mante S, Mand S, Stoffel-Wagner B, Klarmann-Schulz U, Debrah A, Pfarr K, Hoerauf A. Mediators of vascular permeability and lymph/angiogenesis are markers for hydroceles caused by Wuchereria bancrofti infection. 64th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, October 2015 (Oral presentation- Abstract No. 1709).
Klarmann-Schulz U, Batsa L, Specht S, Debrah AY, Osei-Mensah J, Ayisi-Boateng NK, Mubarik Y, Ford L, Konadu P, Mark J. Taylor MJ, Achim Hoerauf. Comparison of doxycycline, minocycline, doxycycline plus albendazole and albendazole alone in their efficacy against onchocerciasis. 64th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, October 2015 (Oral presentation- Abstract No. 639).
Quintana JF, Babayan SA, Makepeace BL, Ivens A, Pfarr K, Debrah A, Wanji S, Taylor DW, Hoerauf A, Buck AH (2015). Secreted filarial small RNAs- Localization in biofluids and biomarker potential for onchocerciasis. 64th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, October2015 (Oral presentation- Abstract No. 443).
Debrah AY, Sabine Specht, Linda Batsa, Ute Klarmann, Sabine Mand, Alexander Kwarteng, Mike Osei-Atweneboana,Daniel Boakye, Ohene Adjei and Achim Hoerauf. Doxycycline treatment shows a strong embryostatic effect and clearance of persistent microfilariae in the skin of onchocerciasis patients in whom repeated ivermectin treatment had failed to clear microfilaridermia. 63rd Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), New Orleans, USA, November 2014 (Oral presentation- Abstract No. 1207).
Debrah AY, Sabine Mand, Henry Atawurah, Nana K. Ayisi-Boateng, Linda Batsa, Alexander Kwarteng, Jubin Osei-Mensah, Yusif Mubarik, Sabine Specht, Arcangelo Ricchiuto, Rolf Fimmers, Achim Hoerauf, Ute Klarmann-Schulz. Long-term improvement of hydrocele size after ultrasound-guided aspiration. 63rd Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), New Orleans, USA, November 2014 (Oral presentation- Abstract No. 1210).
Michelle C. Stanton, Square Z. Mkwanda, Debrah AY, Linda B. Debrah, Achim Hoerauf, Nana-KwadwoBiritwum, Abigail Best, Matthew Cliffe, Louise A. Kelly-Hope. Utilizing the community health worker network for lymphatic filariasis (LF) morbidity monitoring: the development of an SMS-based surveillance tool. 63rd Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), New Orleans, USA, November 2014 (Poster presentation- Abstract No. 1689).
Torres M, Pilotte N, Adjobimey T, Specht S, Terry F, Debrah A, Batsa L, Kwarteng A, de Groot A, Williams S, Hoerauf A. Evaluation of HLA Immunoinformatics for the identification of Brugia malayi putative T cellepitopes conserved with Wuchereria bancrofti andLloa loa. 63rd Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), New Orleans, USA, November 2014 (Poster presentation- Abstract No. 1713).
Batsa L, Debrah AY, Albers A, Mensah J, Brockschmidt F, Becker T, Herold C, Fröhlich H, Lust L, Mand S, Klarmann-Schulz U, Hoerauf A and Pfarr KM. VEGFR3 and other angiogennic/lymphangiogenic genes are associated with development of lymphedema of filarial origin. 62nd Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Washington, USA, November 2013 (Poster presentation- Abstract No.1187).
Debrah A. Sustainability in Research Partnerships - closing critical funding gaps for young post-docs in Africa. 8th European congress on Tropical Medicine and International Health (ECTMIH), Copenhagen, Denmark, September 2013 (Oral presentation- Abstract No.IS 4.9.3.001, Invited speaker).
Linda Batsa, Anna Albers, Jubin Mensah, Felix F. Brockschmidt, Tim Becker, Christine Herold, Holger Fröhlich, Lydia Lust, Sabine Mand, Ute Klarmann-Schulz, Achim Hoerauf and Kenneth M. Pfarr, Debrah A. VEGF-R3 and other angiogennic/lymphangiogenic genes are associated with development of lymphedema of filarial origin. 6th Annual meeting of Ghana Biomedical Convention, Cape Coast, Ghana, July 2013 (Oral presentation- Abstract No.36).
Klarmann U, Debrah AY, Mand, S Linda Batsa, Sabine Specht, Kenneth Pfarr, Alexander Kwarteng, Rolf Fimmers, Mark Taylor, Ohene Adjei, Achim Hoerauf. Shortening the timeframe and dosage of anti-Wolbachia therapy: doxycycline alone versus doxycycline plus rifampicin in their efficacy against lymphatic filariasis; a randomized, double-blind, placebo-controlled trial. 61st Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2012 (Oral presentation- Abstract No.522).
Albers A, Batsa L, Lust L, Mensah J, Brockschmidt F, Becker T, Herold C, Klarmann U, Debrah AY, Hoerauf A, Pfarr K. Genes of the angiogenesis pathway are associated with development of hydrocele in lymphaticfilariasis - a candidate-gene analysis. 61nd Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2012 (Oral presentation- Abstract No.519).
Debrah AY, Batsa L., Albers A., Mand, S., Toliat, M.R., Nürnberg, P., Adjei, O., Hoerauf, A., and Pfarr, K. (2011). Transforming Growth Factor-β 1 variant Leu10Pro is associated with both lack of Microfilariae and differential Microfilarial loads in the blood of people infected with lymphatic filariasis. 1st International Society for Infectious Diseases-Neglected Tropical Diseases Meeting in Boston, Massachusetts, USA. July 2011 (Oral presentation- Abstract No. 07.011).
Debrah AY, Specht S, Mand M, Batsa L, Klarmann U, Marfo-Debrekyei Y, Kwarteng A, Osei-Atweneboana M,Boakye D, Adjei O, Hoerauf A. (2010) Targeting Wolbachia endosymbionts in Onchocerca volvulus effectively clears persistent microfilariae in the skin of onchocerciasis patients in whom repeated ivermectin treatment had failed to clear. 59th Annual Meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2010 (Oral presentation- Abstract No. 1331).
Hoerauf A, Klarmann U, Debrah AY, Batsa L, Adjei O, Mand S. The sensitivity of standard circulating filarial antigen tests and ultrasonography for individual diagnostics and epidemiological surveillance of bancroftian filariasis. 59th Annual meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Atlanta, USA, November 2010 (Oral presentation- Abstract No.1328)
Debrah AY, Mand S, Toliat MR, Marfo-Debrekyei Y, Batsa L, Nuernberg P, Bernard Lawson, Adjei O, HoeraufA, Pfarr K. Targeting endosymbiotic Wolbachia in Wuchereria bancrofti reduces plasma VEGF with amelioration of condition of hydrocele patients. International Congress on Parasitology XII (ICOPA XII) in Melbourne, Australia, August 2010 (Oral Presentation and co-Chairman of one of the symposia- Abstract no. 323).
Debrah AY, Specht S, Mand M, Batsa L, Klarmann U, Marfo-Debrekyei Y, Kwarteng A, Osei-Atweneboana M,Boakye D, Adjei O, Hoerauf A. Targeting Wolbachia endosymbionts in Onchocerca volvulus effectively clears persistent microfilariae in the skin of onchocerciasis patients in whom repeated ivermectin treatment had failed to clear. Biannual Meeting of Royal Society of Tropical Medicine and Hygiene (RSTMH), Liverpool, UK, October 2010 (Poster presentation- Abstract No. P.04).
Batsa L, Specht S, Debrah AY, Mand M, Klarmann U, Marfo-Debrekyei Y, Kwarteng A, Osei-Atweneboana M,Boakye D, Adjei O, Hoerauf A. Targeting Wolbachia endosymbionts in Onchocerca volvulus effectively clears persistent microfilariae in the skin of onchocerciasis patients in whom repeated ivermectin treatment had failed to clear. 6th International Wolbachia Conference. San Francisco, USA. June 2010 (Oral presentation- Abstract No. 7-11).
Mand S, Debrah AY, Specht S, Kwarteng A, Klarmann U, Fimmers R, Batsa L, Marfo-Debrekyei Y, Adjei O, Hoerauf A. Doxycycline improves filarial lymphoedema independent of its action on Wolbachia. 58th Annual Meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Washington, USA, November 2009 (Oral presentation- Abstract No. 1102).
Adjei O, Debrah AY, Mand M, Specht S, Batsa L, Marfo-Debrekyei Y, Pfarr K, Hoerauf A. Macrofilaricidal activity of doxycycline in human onchocerciasis in Ghana. 2nd Annual Scientific Conference of College of Health Sciences of Kwame Nkrumah University of Science Technology, Kumasi, Ghana. November 2009 (Oral presentation- Abstract No. F39).
Debrah AY, Mand S, Toliat MR, Marfo-Debrekyei Y, Batsa L, Nuernberg P, Bernard Lawson, Adjei O, HoeraufA, Pfarr K. Targeting endosymbiotic Wolbachia in Wuchereria bancrofti reduces plasma VEGF-A and improves condition of hydrocele patients. 5th International Wolbachia Meeting in Crete, Greece, June, 2008 (Oral Presentation Abstract no. F2).
Debrah AY, Mand S, Marfo-Debrekyei Y, Batsa L, Adjei O, Pfarr K, Hoerauf A. Onchocerciasis control: Vision for the Future- Antibiotic therapy: Progress from the field - onchocerciasis. A workshop organized by the Royal Society of Tropical Medicine and Hygiene at Elmina, Ghana April 2008. (Oral presentation).
Specht S, Mand S, Debrah AY, Marfo-Debrekyei Y, Adjei O, Geisinger F, Brattig NW, Hoerauf A. Increased immune stimulator after macrofilaricidal therapy . 57th Annual Meeting of American Society of Tropical Medicine and Hygiene (ASTMH), New Orleans, USA, December 2008 (Oral presentation- Abstract No. 383).
Debrah AY, Mand S, Toliat MR, Marfo-Debrekyei Y, Batsa L, Nuernberg P, Bernard Lawson, Adjei O, HoeraufA, Pfarr K. Targeting endosymbiotic Wolbachia in Wuchereria bancrofti reduces plasma VEGF-A and improves condition of hydrocele patients. 56th Annual Meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Philadelphia, USA, November 2007 (Oral presentation and won Travel award for this meeting- Abstract No. 388).
Hoerauf A, Specht S, Buttner M, Pfarr K, Mand S, Filmmers R, Konadu P, Debrah AY, Bandi C, Brattig NW, Albers A, Batsa L, Adjei O, Buettner D. Wolbachia endobacteria depletion by doxycycline as antifilarial therapy is macrofilaricidal in onchocerciasis. 56th Annual Meeting of American Society of Tropical Medicine and Hygiene (ASTMH), Philadelphia, USA, November 2007 (Oral presentation - Abstract No. 389).
Debrah AY, Mand S, Marfo-Debrekyei Y, Batsa L, Pfarr K, Adjei O, Hoerauf A. Effect of targeting endosymbiotic Wolbachia in Wuchereria bancrofti on pathology of filariasis infection. 4th International Wolbachia Meeting in Puerto Rico, Caribbean, June 2006 (Oral Presentation Abstract no A-1).
Debrah AY, Sabine Mand S, Marfo-Debrekyei Y, Batsa L, Pfarr K, Adjei O, Hoerauf A. Evaluation of endosymbiotic Wolbachia DNA in blood as a potential tool for diagnosis of lymphatic filariasis infection. 4thInternational Wolbachia Meeting in Puerto Rico, Caribbean, June 2006 (Oral Presentation Abstract no A-2).
Debrah AY, Sabine Mand S, Marfo-Debrekyei Y, Batsa L, Pfarr K, Adjei O, Hoerauf A. Effect of targeting Endosymbiotic Wolbachia in Wuchereria bancroftian on macrofilaricidal effect, over-expression of VEGF-C/VEGFR-3 and lymphatic dilation in lymphatic filariasis-Results from a 6 weeks trial with doxycycline 22ndGerman Parasitologists Conference in Vienna, Austria. April 2006 (Oral Presentation Abstract no. 23).