Prof. Fareed Kow N. Arthur

Associate Professor

Dept: Biochemistry and Biotechnology
Department of Biochemistry and Biotechnology, KNUST, Kumasi.
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Research Areas/Interests

1. Dyslipidaemia in non-communicated diseases like cancers, hypertension and diabetes 2. Metabolic syndrome in non-communicated diseases 3. Role of hu...~more

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Publications

    1.      Induction of defence responses in Alfalfa (Medicago sativa) cell lines by isolates of Verticillium albo-atrum differing in host specificity (1993).  F K N Arthur, J A Lucas (Abstract).  In ‘Mechanisms of Plant Defence Responses’. B. Fritig and M. Legrand (eds.).  Kluwer Academic Publishers.

    2.      Activation of PI-3 Kinase Pathway by Human Interleukin-17 in Human U937 Leukemia Cells (2002).  Fareed K N Arthur and Samuel Evans Adunyah (Abstract).American Association for Cancer Research (AACR) 93rd Annual Meeting. April 6-10, 2002.  San Francisco. California.

    3.      PI-3K/Akt and Src Kinases Mediate IL-17A-S5timulated TH1 and TH2 Cytokine   Production in Human U937 Leukemia Cells (2003).   Samuel E. Adunyah, Fareed K N Arthur, Richard Akomeah, and Joshua C M Williams (Abstract).  56th Annual Symposium on Fundamental Cancer Research. October 14-17, 2003. Houston, Texas.

    4.      PI-3K/Akt and Src Kinases Mediate IL-17A-stimulated Cytokine Activation In Human U937 Leukemia Cells (2004).  Richard Akomeah, Fareed K N Arthur, Joshua C M Williams and Samuel E Adunyah (Abstract).  American Association for Cancer Research (AACR) 95th Annual Meeting.  March 27-31, 2004. Orlando, Florida.  

    5.      Breast and Cervical Cancer Cases in Ghanaian Hospitals- A Retrospective Study (2005).  F K N Arthur, F A Yeboah, M A Tandoh, and J A Bentil (Abstract).  24th Biennial Conference of the Ghana Science Association. August 1-4th, 2005.  Legon, Accra.

    6.      Evaluation of the indigenous leafy vegetable supplementation for Ghanaian postpartum mothers using MRDR assay (2006).  K.Tchum, S. Newton, S. Tanumihardjo, B. de Benoist, S. Owusu-Agyei, F. Arthur, and A. Tetteh (Abstract).  Bioavailability 2006.  Optimizing Dietary Strategies for Better Health in Developing Countries.  March, 7-10, 2006.  Chiang Mai, Thailand.

    7.      Prostate Cancer Screening in Ghana- A Clinical Benefit? (2006).  F K N Arthur, F A Yeboah, M. Adu-Frimpong, E E Sedudzi, K A Boateng.  Journal of Science and Technology. Vol 26: 1-7.

    8.      Fasting Blood glucose and Glycosylated Haemoglobin levels in Randomly Selected Ghanaian Diabetic Patients- the Clinical Implications (2006).  F K N Arthur, F A Yeboah, K. Nsiah, P K N Nkrumah, K.A Afreh, and K. Agyenim-Boateng.  Journal of Science and Technology. Vol 26: 8-13.

    9.      Prevalence of Erectile Dysfunction among Diabetes and Hypertension Patients at Komfo Anokye Teaching Hospital (2006).  F K N Arthur, D. Boamah, and R S Nyarko (Abstract).  College of Science Research Conference.  July 21-24, 2006.  Takoradi. 

    10.  IL-17A Activates PI-3K/Akt and STATS 3 but not NF-kB during Cytokine Induction and Proliferation in Leukemia Cells (2006).  R. Akomeah, F K N Arthur, C F Fuquah and S E Adunyah.   Proceedings of the 6th Joint Meeting of the International Cytokine Society.  August 27-31, 2006.  Vienna, Austria.

    11.  IL-17A Promotes Cancer Survival and Resistance to Apotosis via Akt-Mediated Inactivation of Caspase 3 and Bad (2006).  S E Adunyah, R Akomeah, F K N Arthur, W. Matthews, C. F. Fuquah, J. Sampson, L. Stewart, and J O Price.  Proceedings of the 6th Joint Meeting of the International Cytokine Society.  August 27-31, 2006.  Vienna, Austria.

    12.  Evaluation of vitamin A supplementation regimens in Ghanaian Postpartum Mothers with the use of the Modified-Relative-Dose-Response Test (2006).  Samuel K. Tchum, Sherry A. Tanumihardjo, Samuel Newton, Bruno de Benoist, Seth Owusu-Adjei, Fareed K. N. Arthur, and Antonia Tetteh.  American Journal of Clinical Nutrition. 84: 1344-1349.

    13.  Relationship Between Body Mass Index, Waist Circumference and Serum Prostate Specific Antigen Levels in the Obese (2008).  F. K. N. Arthur, S. S. Bortse, R. F. Adu, C. A. Appiah, J.N.A. Acheampong and D.Wormenor (Abstract).  2nd College of Science Research Conference, 10-13th July, 2008, Ho.

    14.  Evaluation of a Green Leafy Vegetable Intervention in Ghanaian Postpartum Mothers   (2009).  S.K. Tchum, S. Newton, S. A. Tanumihardjo, F.K.N. Arthur, A. Tetteh, and S. O. Adjei.  African Journal of Food, Agriculture, Nutrition and Development.  9: 1295-1308.

    15.  Burkitt’s Lymphoma: Seven-year Clinical and Epidemiological Characteristics at Komfo Anokye Teaching Hospital in Ghana.  Lawrence Owusu, Francis A. Yeboah, Alexander Y. Osei-Akoto, Theresa Rettig, Arthur K. N. Fareed (2010).  British Journal of Biomedical Science, 69: 9-14.

    16.  Prognosis of African Burkitt’s Lymphoma: A Predictive Model on Ghanaian Children.  F.K.N. Arthur, l. Owusu, F.A. Yeboah, T. Rettig and A. Osei-Akoto (Abstract).  26th Biennial Conference.  Ghana Science Association.  Cape Coast, 4-9th August, 2009.

    17.  Bright Adu, Daniel Dodoo, Selorme Adukpo, Paula L. Hedley, Fareed K. N. Arthur, Thomas A. Gerds, Severin O. Larsen, Michael Chritiansen and Michael Theisen (2012).  Fc Gamma receptor IIIB (FcγRIIIB) polymorphisms are associated with clinical malaria in Ghanaian children.  PLOS one 7: 1-10.

    18.  Fareed K. N. Arthur, Eric Woode, Ebenezer O. Terlabi, and Christopher Larbie (2012).  Evaluation of hepatoprotective effect of aqueous extract of Annona muricata (Linn.) leaf against carbon tetrachloride and acetaminophen-induced liver damage.  Journal of Natural Pharmaceuticals 3: 38-43.

    19.  Fareed KN Arthur, Michael Adu-Frimpong, James Osei-Yeboah, Faustina O Mensah,and Lawrence Owusu (2012).  Prediction of metabolic syndrome among postmenopausal Ghanaian women using obesity and atherogenic markers.  Lipids in Health and Disease 11: 101.

    20.  Fareed K. N. Arthur, Eric Woode, Ebenezer O. Terlabi, and Christopher Larbie (2012).  Bilirubin lowering potential of Annona muricata (Linn.) in temporary-jaundiced rats.  American Journal of Pharmacology and Toxicology 7: 33-40.

    21.  Arthur, F. K. N., Woode, E., Terlabi, E. O. and Larbie, C. (2011).  Hepatoprotective effect of Annona muricata (Linn.) leaves on carbon tetrachloride-induced liver damage in rats (Abstract).  West African Society for Pharmacology Conference (WASP/SOAP).  12-16 July, 2011, Kumasi.

    22.  Arthur, F. K. N., Woode, E., Terlabi, E. O. and Christopher, Larbie (2011).  Hepatoprotective effect of Annona muricata (Linn.) on acetaminophen-induced liver damage in rats.  (Poster Abstract).  4th Ghana Biomedical Convention, 27-29 July, 2011, Kumasi.

    23.  Arthur, F. K. N., Woode, E., Terlabi, E. O., and Larbie, C. (2011).  Evaluation of acute and subchronic toxicity of Annona muricata (Linn.) aqueous extract in animals.  European Journal of Experimental Biology, 1: 115-124.  

    24.  Fareed Kow Nanse Arthur, Lawrence Owusu, Francis Agyeman, Theresa Rettig, Alex Osei-Akoto (2011).  Prognostic significance of biochemical markers in African Burkitt’s lymphoma.  Clinical and Translational  Oncology, 13:731-736.

    25.  Joseph K. Kwarteng, Mensah, F. O., Nsiah, K., and Arthur, F. K. N. (2011).   Changes in lipid metabolism associated with progressive liver damage in chronic hepatitis B infection (Abstract).  4th Ghana Biomedical Convention, 27-29 July, 2011, Kumasi..

    26.  J. K. Kwarteng, L. Owusu, M. Afihene, E. Mica, O. Opare-Sem and F. K. N. Arthur (2012).  Lowered serum trglyceride levels among Chronic Hepetitis B-Infected patients in Ghana.  Journal of Science and Technology, 32:1-10

    27.  Fareed Kow Nanse Arthur, Michael Adu-Frimpong, James Osei-Yeboah, Faustina Obu Mensah and Lawrence Owusu (2013).  The prevalence of metabolic syndrome and its predominant components among pre- and postmenopausal Ghanaian women.  BMC Research Notes, 6:446.

    28.  Charles Apprey, Reginald A. Annan, Fareed K. N. Arthur, Samuel K. Boateng and Janet Animah (2014).  The assessment and prediction of malnutrition in children suffering from cancer in Ghana.  European Journal of Experimental Biology, 4: 31-37.

    29.  Arthur, F.K. N., Dadson J. K., Yeboah-Awudzi, M., and Larbie,C. (2014).  Body mass index and its effects on the rate of hospital visits of staff of the Kwame Nkrumah University of Science and Technology, Kumasi.  Archives of Applied Science Research, 6:198-202.

    30.  Charles Apprey, Christopher Larbie, Reginald A. Annan, Fareed K. N. Arthur, Samira Abdulai-Saiku, Doris Berkoh and Alex Osei-Akoto (2015).  Effects of chemotherapy and disease burden on the nutritional status of patients undergoing treatment for Burkitt’s lymphoma.  Der Pharmacia Lettre, 7: 95-99.

    31.  C. Apprey, C. Larbie, F. K. N. Arthur, R. Appiah-Opong, R. A. Annan and I. Tuffour (2015).  Antiproliferative effect of isoflavones isolated from soybean and soymilk powder on lymphoma (DG) and leukemia (CEM) cell lines.  British Journal of Pharmaceutical Research, 7: 206-216.

    32.  Felix Acheampong, Christopher Larbie, Regina Appiah-Opong, Fareed K. N. Arthur and Isaac Tuffour (2015).  In vitro antioxidant and anticancer properties of hydroethanolic extracts and fractions of Ageratum conyzoides.  European Journal of Medicinal Plants, 7: 205-214.

    33.  Felix Acheampong, Christopher Larbie, Fareed K. N. Arthur, Regina Appiah-Opong and Isaac Tuffour (2015).  Antioxidant and anticancer study of Ageratum conyzoides aqueous extract.  Journal of Global Biosciences, 4: 1804-1815

     

    34.  Bright Adu, Mariama K. Cherif, Samuel Bosomprah, Amidou Diarra, Fareed K. N. Arthur, Emmanuel K. Dickson, Giampietro Corradin, David R. Cavanagh, Michael Theisen, Sodiomon B. Sirima, Issa Nebie and Daniel Dodoo (2016).  Antibody levels against GLURP R2, MSP 1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas. Malaria Journal, 15: 123.

     

    35.  L.J.J. Gowans, W. L. Adeyemo, M. Eshete, P. A. Mossey, T. Busch, B. Aregbesola, P. Donkor, F. K. N. Arthur, S. A. Bello, A. Martinez, M. Li, E. A. Augustine-Akpan, W. Deressa, P. Twumasi, J. Olutayo, M. Deribew, P. Agbenorku, A. A. Oti, R. Braimah, G. Plange-Rhule, M. Gesses, S. Obiri-Yeboah, G. O. Oseni, P. B. Olaitan, L. Abdur-Rahman, F. Abate, T. Hailu, P. Gravem, M. O. Ogunlewe, C. J. Buxo, M. L. Marazita, A. A. Adeyemo, J. C. Murray, and A. Butali (2016).  Association studies and direct DNA sequencing implicate genetic susceptibility loci in the etiology of nonsyndromic orofacial clefts in sub-Saharan African populations.  Journal of Dental Research, 95:1245.

    36.  Lord J. J. Gowans et al. (2017). The prevalence, penetrance, and expressivity of etiologic IRF6 variants in oro-facial clefts patients from sub-Saharan Africa. Molecular Genetic and Genomic Medicine. Doi: 10.10002/mgg3.273 

    37.  Lord Jephthah Joojo Gowans, Solomon Obiri Yeboah, Alexander Acheampong Oti, Fareed Kow Nanse Arthur, Peter Twumasi, Pius Agbenorku, Gyikua Plange-Rhule, Peter Donkor (2018).  Non-Random Distribution of Human Orofacial Clefts in Ghana: Gene-Envronment Interactions.  Open Journal of Stomatology.  DOI: 10.4236/ojst. 2018.81002

    38.  Azeez Butali, Peter A. Mossey, Wasiu L. Adeyemo et al (2019).  Genomic analyses in African populations identify novel risk loci for cleft palate.  Human Molecular Genetics, 28 : 1038-1051.

    39.  Charles Apprey, Reginald A. Annan, Fareed K. N. Arthur, Christopher Larbie, and Alex O. Akoto (2018).  Nutritional intervention in children undergoing chemotherapy for cancer.  Journal of Cancer and Tumor International, 7:1-11.

    40.  Christopher Antwi, Patience A. Mensah, Samuel Asamoah Sakyi, Fareed K. N. Arthur, Yaw O. Frimpong, Antoinette Simpah Anim Jnr. and John Baah (2020).  Direct fed microbials and their influence on blood biochemistry, immunology of lambs and Escherichia Coli count.  Biomedical Journal Sci & Tech. Research, 26.  BJSTR, MS. ID. 004401

    41.  Christopher Antwi, Patience A. Mensah, Fareed K. N. Arthur, Yaw O. Frimpong, and John Baah (2019).  Feeding differing direct-fed microbials and its influence on growth and haematological parameters on growing lambs.  Transl. Anim. Sci. doi: 10. 1093/tas/txz053.

    42.  Samuel Kofi Tchum, Fareed Kow Arthur, Bright Adu, Samuel Asamoah Sakyi, Latifatu Alhassan Abubakar, Dorcas Atibilla, Seeba Amenga-Etigo, Felix Boakye Oppong, Francis Dzabeng, Benjamin Amoani, Thomas Gyan, Emmanuel Arhin and Kwaku Poku-Asante (2021).  Impact of iron fortification on anaemia and iron deficiency among pre-school children living in Rural Ghana. Doi.org/10.1371/journal.pone.0246362

    43.  Lord J. J. Gowans, Noura A Dhaheri, Mary Li , Tamara Busch , Solomon Obiri-Yeboah , Alexander A. Oti , Daniel K. Sabbah , Fareed K. N. Arthur , Waheed O. Awotoye , Azeez A. Alade , Peter Twumasi,  Pius Agbenorku,  Gyikua Plange-Rhule,  Thirona Naicker , Peter Donkor, Jeffrey C. Murray,  Nara L. M. Sobreira , Azeez Butali (2021). Co-occurrence of orofacial clefts and clubfoot phenotypes in a sub-Saharan African cohort: Whole-exome sequencing implicates multiple syndromes and genes.  Molecular Genetics & Genomic Medicine. DOI:10.1002/mgg3.1655. 

    44.  Azeez A. Alade et al. (2020). Non-random distribution of deleterious mutations in the DNA and protein-binding domains of IRF6 are associated with Van Der Woude syndrome.  Molecular Genetics & Genomic Medicine.  DOI:10.1002/mgg3.1355.

     

     

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