Dr. Charles Apprey


Dept: Biochemistry and Biotechnology

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Research Areas/Interests

Clinical Nutrition  Clinical Biochemist...~more

My full CV


Dr. Charles Apprey is a lecturer and researcher at the Department of Biochemistry at the Kwame Nkrumah University of Science and Technology with expertise is in the area of Clinical and Nutritional Biochemistry. My research interest has been in the area of nutrition interventions in non-communicable diseases including cancer and other cardiovascular diseases such as obesity, diabetes and hypertension. My PhD research focused on nutrition intervention study in children who were undergoing chemotherapy treatment for childhood cancers (Burkitt’s Lymphoma and Wilm’s tumour). The aim of this research was to look at the impact of high protein based supplement Soymilk powder (SMP) on nutritional status and recovery among children undergoing treatment for Burkitt’s Lymphoma and Wilm’s tumour at the Komfo Anokye Teaching Hospital, Kumasi. Anthropometric and Biochemical markers including Zinc, Pre-albumin, reduced glutathione and heamoglobin were measured. We went further to investigate the anti-proliferative effect of isoflavanoids isolated from SMP on Burkits’s lymphoma (DG-75) and Leukaemia (CEM) cell lines.

Over the past 5 years I have been involved in a number of research and a recipient of grant from Nestle Foundation to investigate the underlying causes of malnutrition in pregnant adolescents in Ghana. In Ghana, iron folate supplementation for pregnant women has been part of antenatal care interventions for over 15 years now. However, iron deficiency anaemia remains a significant problem in the country and among pregnant women.  I served as a co-PI on this project and also led the assessment of the various biochemical indicators including haemoglobin, serum pre-albumin, ferritin, zinc protophophyrin, vitamin A, total anti-oxidant capacity, and C-Reactive protein to adequately measure nutritional deficiencies in these participants. This was combined with the dietary assessment and anthropometrics to give us a better overview of the nutritional status of these participants.

I have also been involved in the Researching the obesogenic food environment in Ghana and South Africa a research funded by the International Development Research Centre, Canada.  This was a collaborative study between KNUST and university of Western Cape. I served as the lead on the phase one in Ghana which looked at household food consumption and purchasing patterns and how this is influencing obesity and other cardiovascular conditions among residents of Ahodwo and Ejuriatsea in the Ashanti Region.

Together with colleagues in the University of Tokyo we have also been working in the area of exploring the effectiveness of nutrition and physical fitness intervention programme in basic schools to address the prevalence of childhood obesity which has been documented as the major causes of adult obesity and its resultant cardiovascular conditions. I served as a Co-PI on this project.

I have also been a lead PI on a project to exploring the effectiveness of Borassus aethiopium fortified bread in reducing the metabolic risk factors of CVD patients. In this intervention we measured biochemical lipid profile before and after the interventions.

I have about 5 years of teaching experience in the University and have taught undergraduate and Postgraduate students in various programmes including; BSc. Biochemistry, BSc. Food Science and Technology, BSc. Medical Lab. Technology, BSc. Natural Resource Management, BSc. Aquaculture, MPhil Human Nutrition and Dietetics and MSc. Human Nutrition and Dietetics. I have supervised 27 undergraduate students, 31 postgraduate students and 5 PhD students for these period I have served in the university. I have also served as internal examiner for over 20 PhD, MPhil and MSc student in Human Nutrition and Dietetics at the KNUST. Currently, I have 37 publications in peer reviewed journals.

Currently am an external examiner for the Department of Nutrition at the University of Ghana and Lilongwe University of Agriculture and Natural Resource, Malawi. I have also served as a reviewer for a number of International Journals some of which include; Nutrition and Cancer Journal, Asian Food Science Journal, International Journal of Tropical Diseases and Health, Plos One, Journal of Advances in Medicine and Medical Research among others. I am currently the Programme Coordinator for the PhD/MPhil/MSc. Human Nutrition and Dietetics at the KNUST and the Department Examinations Officer.

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