Seth is a Lecturer in the Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Ghana. He is a certified Medical Laboratory Scientist by the Allied Health Professions Council, Ghana, and has over a decade of clinical laboratory practice before joining KNUST.

Seth holds a BSc in Medical Laboratory Technology and an MPhil in Immunology from KNUST. Also, he has a PGDip in Teaching and Learning in Higher Education from the University of Education Winneba, Ghana. He was a WACCBIP-DELTAS PhD Fellow and graduated with a PhD in Molecular Cell Biology of Infectious Diseases from the University of Ghana, Legon. His mission is to use the knowledge in immuno-molecular cell biology to bring about an increased impact on healthcare interventions in Africa, specifically malaria and viral hepatitis B elimination.

Seth previously worked on the molecular mechanisms through which cryptolepine, an alkaloid in Cryptolepis sanguinolenta, modulates the type 1 interferon response, inhibits hepatocellular carcinoma cell growth and suppresses hepatitis B virus replication. Also, he has worked on the molecular mechanisms through which high glucose levels modulate the immune response in type 2 diabetes mellitus.

Currently, Seth is moving into the area of malaria transmission research. He focuses on discovering therapeutics blocking malaria parasite transmission and identifying the genetic variations in parasites causing antimalarial drug resistance. Seth also aims to unravel how toxins or genes collaborate with the hepatitis B virus to increase hepatocarcinogenesis and identify therapeutic targets.

Seth teaches undergraduate and postgraduate courses that include cell biology, molecular biology, biomolecular techniques, and molecular medicine.