Prof. Isaac Ayensu

Professor


Dept: Pharmaceutical Chemistry
Room C307, Third Floor, Tackie Building
Department of Pharmaceutical Chemistry
Faculty of Pharmacy KNUST

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Research Areas/Interests

Pharmaceutical analysis, characterization and quality control, Novel drug formulation and development. Medicinal Chemistry Novel Application of h...~more

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Research Projects (Current and Past)

On-going projects

  1. Filtration systems for water bodies contaminated by heavy metals from mining activities and Pharmaceutical residues.
  2. Development and Validation of Stability indicating HPLC Method for the Simultaneous Estimation of Selected Analgesics
  • Anti-Infective Extracts and Phytoconstituents Isolated from Zea Mays and other Ghanaian Medicinal Plants
  1. Synthesis of ‘clicked’ compounds and their phosphonium salts as targets against some tropical infections.
  2. Isolation, characterization and microbial assay of a biomarker (Bergenin) and development of RP-HPLC method for the quality control of the roots of securinega
  3. Detection and quantification of aphrodisiac adulterants in alcoholic beverages in Ghana
  • Qualitation and Quantification of Tryptophan in Hausa Koko (Spicy Millet Porridge): A Ghanaian Beverage
  • Evaluation of the Anticancer, Antioxidant and Phytochemical Constituents of Adansonia Digitata (Malvaceae)
  1. Novel Application of hydrotropic Solubilization technique in the formulation and analysis of poorly soluble drugs
  2. Phytochemical Screening, Antimicrobial, Antioxidant and Anti-inflammatory activities of various extracts of the leaves and stem bark of Allanblackia parviflora (A Chevalier)
  3. Novel Application of hydrotropic Solubilization technique in the formulation and analysis of poorly soluble drugs
  • Comparative quantitative and activity analysis of antibiotics. Case study of NHIS and non-NHIS medicines
  • Determination of levels of lead in popularly patronised cosmetic products
  • Antimicrobial activities and phytochemical screening of the stem bark Of Trichilia tessemannii (Harms) of the family Meliaceae.
  1. Development characterisation of laminated thiolated chitosan-based lyophilisedxerogels for potential buccal delivery of macromolecules.
  • Effect of protease enzyme inhibitors on mucoadhesion and release kinetics of macromolecules from laminated thiolated-chitosan freeze-dried xerogels.


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