Prof. Raphael Johnson

Associate Professor


Dept: Pharmaceutics
Room B103
Department of Pharmaceutics
Faculty of Pharmacy and Pharmaceutical Sciences

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Research Areas/Interests

Structure investigation of pharmaceutical, biological macromolecules and membranes using combined dynamic light scattering and neutron scattering. ...~more


Publications

    1. Kuntworbe N., Acquah F.A., Johnson R., Ofori-Kwakye K. 2018. Comparison of the physicochemical properties and in vitro bioavailability of generic and innovator artemether-lumefantrine tablets in Kumasi, Ghana. Journal of Pharmacy and Pharmacognosy Research, Vol. 6(3), pp 167-178.
    1. Mensah A., Kuntworbe N., Johnson R., Ofori-Kwakye K. 2017. Qualitative and quantitative assessment of cryptolepis-based herbal formulations within Accra and Kumasi metropolis in Ghana. Journal of Innovations in Pharmaceutical and Biological Sciences, Vol. 4(1), pp 58-65.
    2. Khoshakhlagh P., Johnson R., Nawroth T.,  Langguth P., Schmueser L., Decker H., Hellmann N., Szekely N. 2015. Fasted-state simulated intestinal fluid “FaSSIF-C”, a cholesterol containing intestinal model medium for in vitro drug delivery development. J. Pharm. Sci. Vol. 104, Issue 7, pp 2213–2224.
    3. Johnson R, Khoshakhlagh P, Nawroth T, Langguth P, Schmueser L, Decker H, Hellmann N, Szekely N. 2014. Amphotericin B microparticles ‘AmbiShell’ from phospholipid and gelatin: Development and investigation by combined DLS and SANS resolves the core-shell structure. Eur. J. Lipid Sci. Technol., Vol 116, pp 1167 – 1173.
    4. Khoshakhlagh P., Johnson R., Nawroth T.,  Langguth P., Schmueser L., Decker H., Hellmann N., Szekely N. 2014. Nanoparticle structure development in the gastrointestinal model fluid FaSSIFmod6.5 from several phospholipids at various water content relevant for oral administration. Eur. J. Lipid Sci. Technol., Vol 166, pp 1155 – 1166.
    5. R. Johnson, M.T. Bayor, J. Adotey, 2011. Formulation and evaluation of herbal capsules of the extracts of Bridelia ferruginea leaf and Canthium glabriflorum stem bark. International Journal of Contemporary Research and Review, Vol 2 (1), pp 6 - 10.
    6. M. T. Bayor, R. Johnson, S.Y. Gbedema, 2011. The Oral Capsule – The most appropriate dosage form for Croton Membranaceus. International Journal of Pharmaceutical Sciences and Research, Vol 2 (1), pp 55 – 62.
    7. Yaa Asantewaa, K. Ofori Kwakye, S. L. kipo, Vivian Etsiapa Boamah and Raphael Johnson, 2011. Investigation of the emulsifying and suspending potential of Cashew tree gum in Pharmaceutical formulations. International Journal of Pharmacy and -Pharmaceutical Sciences, Vol 3, Issue 3, pp 215 – 219.
    8. R. Johnson, M.T. Bayor, J. Adotey, K. Annan, 2010. Release profile of extracts of Bridelia ferruginea leaf and canthium glabriflorum stem bark from different absorbents. International Journal of Pharmaceutical Sciences and Research, Vol 1, 8 (suppl), pp 111 – 117.

    Other Publications

    Books

    1. Raphael Johnson (2015). Amphotericin B Nano-formulations: Development, characterisation and suitability for oral administration. PhD Thesis, Fachbereich Chemie, Pharmazie und Geowissenschaften, Johannes Gutenberg Universität, Mainz, Germany.
    2. Raphael Johnson (2006). Formulation of Camber and Bredina Liquid Dosage Forms into Capsules. Master’s Thesis, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

     Abstracts

    1. Raphael Johnson, Pooneh Khoshakhlagh, Thomas Nawroth, Peter Langguth, Lidija Krebs, Heinz Decker, Nadja Hellmann, Noemi Szekely., Development and structure evaluation of lipid nanoformulations of Amphotericin B for oral administration. Phospholipids in Pharmaceutical Research, Heidelberg, Germany, 21st -22nd September, 2015.
    2. Thomas Nawroth, Raphael Johnson, Pooneh Khoshakhlagh, Lidija Krebs, Karl Buch, Peter Langguth, Guenther Goerigk, Peter Boesecke, Alberto Bravin, Géraldine Le Duc, Noemi Szekely, Ralf Schweins. Target Nanoparticles for Therapy – SANS and DLS of Drug Carrier Liposomes and Polymer. Proceedings of 6th European conference on Neutron science, Zaragoza, Spain, 30th Aug – 4th September, 2015
    3. Nawroth Thomas, Pooneh Khoshakhlagh, Raphael Johnson, Lidija Krebs, Peter Langguth, Noemi Szekely, Patrick Augustijns. Human intestinal fluids HIF, and FaSSIF-C, a cholesterol containing intestinal model fluid: Comparison and nano-structure by dynamic light scattering DLS and neutron scattering SANS. OrBiTo open science day, Chilly-Mazarin, France, 1st July, 2015.
    4. Nawroth Thomas, Pooneh Khoshakhlagh, Raphael Johnson, Lidija Krebs, Sarah Kindgen, Regine Rach, Peter Langguth, Lars Schmueser, Nadja Hellmann, Heinz Decker, Tobias Schrader, Noemi Szekely. Nano-structure dynamics in gastro-intestinal models for drug delivery. International Conference on Surfaces and Colloid Science (IACIS), Mainz, Germany, 24th – 29th May, 2015
    5. Johnson R, Khoshakhlagh P, Nawroth T, Langguth P, Schmueser L, Decker H, Hellmann N, Szekely N., Structural Dynamics of Liposomal Amphotericin B in FaSSIF by combined SANS and DLS. Trends in Neutron Science – MLZ User Meeting, Ismaning, Munich, Germany, 23rd – 24th February, 2015.
    6. Nawroth, P. Khoshakhlagh, S. Kindgen, L. Krebs, R. Johnson, P. Langguth, N. Szekely and R. Schweins., Gastro-Intestinal Simulator for in vitro Drug and Nanoparticle Tracing in Oral Drug Development. Deutsche Pharmazeutische Gesellschaft Annual meeting, Frankfurt, Germany, 24th – 26th September, 2014, p 81.
    7. Khoshakhlagh P., Johnson R., Nawroth T., Langguth P., Schmueser L., Decker H., Hellmann N., Szekely N., Structural Dynamics of Novel Gastrointestinal Model Fluids by combined SANS and DLS . Deutsche Pharmazeutische Gesellschaft Annual meeting, Frankfurt, Germany, 24th – 26th September, 2014, p 194.
    8. Johnson R, Khoshakhlagh P, Nawroth T, Langguth P, Schmueser L, Decker H, Hellmann N, Szekely N., Structural Dynamics of Liposomal Amphotericin B in FaSSIF by combined SANS and DLS. Deutsche Pharmazeutische Gesellschaft Annual meeting, Frankfurt, Germany, 24th – 26th September, 2014, p 196.
    9. Johnson R, Khoshakhlagh P, Nawroth T, Langguth P, Schmueser L, Decker H, Hellmann N, Szekely N., Oral Amphotericin B Nano-Formulations: Structure and Development in Gastrointestinal Fluids. ORBITO Workshop, Mainz, Germany, 17th – 19th September, 2014.
    10. Nawroth, P. Khoshakhlagh, R. Johnson, P. Buch, P. Langguth, L. Schmueser, N. Hellmann, H. Decker, N. Szekely and R. Schweins., Nanoparticles in the human Gastro-Intestinal System and Drug Uptake – Modelling and Investigation by Time Resolved Neutron Scattering. Neutrons in Biology and BioTechnology, Grenoble, France, 19th-21st February 2014.
    11. Raphael Johnson, Pooneh Khoshakhlagh, Thomas Nawroth, Peter Langguth, Lars Schmueser, Heinz Decker, Nadja Hellmann, Noemi Szekely., Amphotericin B lipid Nanoparticles for oral administration. Deutsche Pharmazeutische Gesellschaft Annual meeting, Freiburg, Germany, 9th – 11th October, 2013, p 244.
    12. Khoshakhlagh P., Nawroth T., Johnson R., Langguth P., Schmueser L., Decker H., Hellmann N., Szekely N., Gastrointestinal BCS 2-drug resolution in intestinal model fluids containing physiological lipids-drug dissolution and intestinal nanoparticle structure estimated by DLS and neutron scattering. Deutsche Pharmazeutische Gesellschaft Annual meeting, Freiburg, Germany, 9th – 11th October, 2013, p 129.
    13. Raphael Johnson, Pooneh Khoshakhlagh, Thomas Nawroth, Peter Langguth, Lars Schmueser, Heinz Decker, Nadja Hellmann, Noemi Szekely., Structural dynamics of lipid complexes of Amphotericin B. Phospholipids in Pharmaceutical Research, Heidelberg, Germany, 16th -17th September, 2013.
    14. Khoshakhlagh P., Nawroth T., Johnson R., Langguth P., Schmueser L., Decker H., Hellmann N., Szekely N., Lipid-drug nanoparticles in gastrointestinal model fluids. Phospholipids in Pharmaceutical Research, Heidelberg, Germany, 16th -17th September, 2013.
    15. Nawroth, P. Khoshakhlagh, R. Johnson, P. Buch, P. Langguth, L. Schmueser, N. Hellmann, H. Decker, N. Szekely and R. Schweins., Drug-uptake by Nanostructures in the GI-System: Simulator with DLS-SANS. Innovative Tools for Oral Biopharmaceutics OrBiTo, Uppsala, Sweden, 26th-27th June 2013.
    16. Johnson R., Adotey J., Kipo S.L., A method of converting decoctions into solid dosage form. Proceedings of the 1st Annual Scientific Conference of College of health Sciences, KNUST, Kumasi, Ghana, 28th – 29th August, 2008, p 52.

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