Prof. Merlin Lincoln Kwao Mensah

Part Time Associate Professor

Dept: Herbal Medicine
Department of Herbal Medicine, Faculty of Pharmacy and Pharmaceutical Sciences, KNUST.

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Research Areas/Interests

i). Bioactivity studies and isolation of medicinal plant constituents ii).Evaluation and standardization of Ghanaian medicinal plants iii). Clinical s...~more

My full CV


    1. Ofori Agyemang A, Amponsah I, Mensah M, Turkson B, Baidoo M, Orman E, Bayor M. Utilization of Plants for Medicinal Purposes and Concerns with Endangered Plant Species from Ghana. Trad Integr Med. 6(1):24-40
    2. Authentia Sokpe, Merlin L. K. Mensah, George A. Koffuor, Kwesi P. Thomford, Richmond Arthur, Yakubu Jibira, Michael K. Baah, Bright Adedi, Hope Y. Agbemenyah, "Hypotensive and Antihypertensive Properties and Safety for Use of Annona muricata and Persea americana and Their Combination Products", Evidence-Based Complementary and Alternative Medicine, vol. 2020, Article ID 8833828, 13 pages, 2020.
    • Yankyera, BO, Turkson, BK, Mensah, MLK. Toward understanding the ‘Kooko’syndrome in traditional medicine in Ghana (2020) History & Philosophy of Medicine 2 (3), 81-90. DOI: 12032/HPM20200724016
    1. Turkson, B.K., Mensah, M.L.K., Amponsah, I.K., Mensah, A.Y., Achaab, E., Mensah, R.B., Atakorah, E., Attah, E.O., Zoiku, F. 2020. In vitro and in vivo Activity of Mist Amen Fevermix and Edhec Malacure, Polyherbal Antimalarial Products on Field Isolates of Plasmodium falciparum and Plasmodium berghei. Discovery Phytomedicine 7(3): 97-102. DOI: 10.15562/phytomedicine.2020.129
    2. Turkson, K, Mensah, M L K  , Sam, GH, Mensah, A.Y., Amponsah, I.K., Ekuadzi E, Komlaga, G. , Achaab, E.  (2020) Evaluation of the Microbial Load and Heavy Metal Content of Two Polyherbal Antimalarial Products on the Ghanaian Market. Evid Based Complement Alternat Med. DOI: 10.1155/2020/1014273
    3. Agyemang, A.O., Mensah, M.L.K., Yamile, R.C., Ocloo, A., Appiah, A.A., Mensah, A.Y., and Thomford, K.P. (2020) 'Clinical Evaluation of the Safety and Effectiveness of Heptonica: A Ghanaian Hepatorestorative Polyherbal Product', Evidence - Based Complementary and Alternative Medicine, 2020. DOI:10.1155/2020/9596182
    • Tetteh AW, Thomford KP, Mensah ML, Boadu KO, Thomford AK, Amposah IK, Amofa G, Turkson BK, Agyemang MO, Owusu-Ansah ED.(2020), Ghanaian herbal medicines for malaria: An Evaluation of the Clinical Safety and Effectiveness of “Time Herbal Mixture” in uncomplicated malaria. Phcog Res 2020;12:71-5
    • Tetteh AW, Thomford KP, Mensah ML, Boadu KO, Thomford AK, Agyeman MO, Annan K, Dickson RA, Mensah AY, Amponsah IK, Ekuadzi E, Owusu-Ansah ED, Amofa G, Turkson B, Agyemang MO, Owusu-Ansah E, (2020). Ghanaian herbal medicines: An evaluation of the clinical safety and effectiveness of Time Herbal Mixture in uncomplicated malaria.  Pharmacognosy Research. DOI: 10.4103/pr.pr_23_19
    1. Mary TA, Edmund E, Priscilla MK, Mariam BE, Mensah, MLK, Eric W.(2019) Pharmacognostic Studies of the Leaves, Stem and Root of Capparis erythrocarpos Isert (Capparaceae). Pharmacog J.;11 (1):112-8.
    2. Thomford KP, Thomford AK, Akoto BO, Appiah AA, Yeboah R, Mensah ML. (2019). An Open Label Clinical Study Evaluating the Effectiveness of a Cryptolepis sangujnolenta based Herbal Antimalarial Agent. J. Biomed. Res. Vol. 22; 257- 262
    3. Turkson, BK Mensah, MLK and Sarpong, K. (2019) Clinical Evaluation of Efficacy of a Herbal Formulation Used in the Treatment of Malaria. European J Med Plants 27(3): 1-7
    • Appiah B, Amponsah IK, Poudyal A. and Mensah, MLK,(2018) Identifying strengths and weaknesses of the integration of biomedical and herbal medicine units in Ghana using the WHO Health Systems Framework: a qualitative study. BMC Complementary and Alternative Medicine. org/10.1186/s12906-018-2334-2.
    1. Kwesi Prah Thomford, Merlin Lincoln Kwao Mensah, Rita Akosua Dickson, Ama Kyeraa Thomford, Alfred Ampomah Appiah and Stephen Yao Gbedema. Appraisal of the Constituent Plant Materials in a Ghanaian Antifungal Herbal Product; An in vitro Interactive Combination Analysis and a Pilot Clinical Study to Determine Efficacy. International Journal of Phytomedicine 2018;10(4):219-225 DOI:10.5138/09750185.2248
    2. Komlaga, G., Grégory Genta-Jouve, Sandrine Cojean, Rita A. Dickson, Merlin L.K. Mensah, Philippe M. Loiseau, Pierre Champy, Mehdi A. Beniddir (2017). Antiplasmodial Securinega alkaloids from Phyllanthus fraternus: Discovery of natural (+)-allonorsecurinine. Tetrahedron Letters 58; 3754–3756,
    3. Dade, J, Kablan, L, Attioua, B, Bories C, El Hadji Bamba S, Mensah, M and Komlaga, G. (2017) Antileishmanial and Trypanocidal Activities of Extracts and Aporphine Alkaloids Isolated from Monodora Genus (Annonaceae). J Pharmacogn Nat Prod 3: 136. doi:4172/2472-0992.1000136
    • Tetteh AW, Mensah MLK, Boadu KO, Thomford KP, Agyeman MO, Annan K, Dickson RA, Mensah AY, Amponsah IK, Ekuadzi E, Owusu-Ansah ED. (2017). Clinical Evaluation of the Safety and Effectiveness of Adutwumwaa Malamix: A Polyherbal Product for the Treatment of Uncomplicated Malaria In Ghana. J App Pharm Sci, 7 (07): 40-45
    1. Gustav KOMLAGA, Sandrine COJEAN, Rita A. DICKSON, Mehdi A. BENIDDIR,

    Soulaf SUYYAGH-ALBOUZ, Merlin L. K. MENSA, Christian AGYARE, Pierre

    CHAMPY, Philippe M. LOISEAU (2016). "Antiplasmodial activity of selected medicinal plants used to treat malaria in Ghana, Parasitol. Res. 115(8):3185-95. doi: 10.1007/s00436-016-5080-8.


    1. Evelyn Afua Mireku, Merlin L.K. Mensah, Abraham Yeboah Mensah (2016) Prenylated Indole alkaloids from the stem bark of Hexalobus Monopetalus. Phytochemistry Letters 16: 108-114
    2. Komlaga, G., Agyare, C., Dickson, R. A., Mensah, M. L. K., Annan, K., Loiseau, P. M., & Champy, P. (2015). Medicinal plants and finished marketed herbal products used in the treatment of malaria in the Ashanti region, Ghana. Journal of Ethnopharmacology, 172, 333-346.
    • Turkson, B. K., Kofi, P. O., Achaab, E., Woyome, Y., Mensah, M. L., Sarpong, K., & Abraham, Y. (2015). Clinical Evaluation of the Effectiveness and Safety of Mist Amen Fevermix, a Ghanaian Bi-Herbal Product, Used in the Management of Uncomplicated Malaria. Journal of Natural Sciences Research, 5(10), 28-33
    • Thomford, K. P., Mensah, M. L. K., Dickson, R. A., Sarfo, B. S., Edoh, D. A., Mills-Robertson, F. C., & Annan, K. (2015). A randomized double-blind study evaluating the safety and effectiveness of a Ghanaian polyherbal product for the management of superficial mycoses. Journal of Herbal Medicine, 5(3), 140-146.
    1. Thomford K.P, Mensah M.L.K, Dickson R.A, Edoh D.A, Safo, B.S, Annan K, (2015). Determination of the Rutin, Quercetin and Kaempferol Contents in a Ghanaian Polyherbal Formulation (EAF-2011) and Its Raw Materials Using a Simultaneous RP-HPLC Method. Int J of Pharm Sc and Drug Res 7(1): 96-99.
    2. Jackson, N., Annan, K., Mensah, AY., Ekuadzi, E, Mensah, M.L.K. and Habtemariam, S (2015). A Novel Triterpene from the Roots of Paullinia pinnata: 6α-(3’-methoxy-4’-hydroxybenzoyl)-lup-20(29)-ene-3-one. Natural Product Communications. 10 (4) 563-5642015
    3. Thomford K.P.,Yeboah R., Thomford A.K., Edoh, D.A., Mensah, M.L.K., Appiah, A.A. (2015). A Retrospective Clinical Study on the Effectiveness of the Aqueous Leaf Extract of Bredelia ferrugenia (Benth) in the Management of Diabetes Mellitus. Int J of Herb Med. 2 (5): 20-26.

    Antimicrobial and Antioxidant Activities of the Stem Bark of Cussonia bancoensis  J. of Medical and Biomedical Sciences 3(2): 7-13  

    1. Mensah A.Y., Mireku E.A., Mensah M.L.K., Amponsah I.K.( 2014) Some neurological effects of the ethanolic stem bark extract of Cussonia bancoensis Aubrev and Pellgr (Araliaceae), Journal of Pharmacognosy and Phytochemistry; 2 (6): 101-106.
    • Isaac Kingsley Amponsah, Abraham Yeboah Mensah Antonia Otoo, Merlin Lincoln Kwao Mensah, Jato Jonathan (2014). Pharmacognostic standardisation of Hilleria latifolia (Lam.) H. Walt. (Phytolaccaceae). Asian Pac J Trop Biomed 2014; 4(12): 941-946 . doi: 10.12980/APJTB.4.2014APJTB-2014-0416
    • Komlaga, G, Sam, G.H., Dickson, R. A, Mensah, M.L.K., Fleischer, T. C. (2014) Pharmacognostic Studies and Antioxidant Properties of the Leaves of Solanum macrocarpon. Pharm. Sci. & Res. Vol. 6(1), 1 - 4
    • A. Sarkodie, T.C. Fleischer , D.A. Edoh , R.A. Dickson , M.L.K. Mensah, K. Annan, E. Woode, G.A. Koffour, A.A. Appiah and H. Brew-Daniels. Antihyperglycaemic Activity of Ethanolic Extract of the Stem Adenia lobata  Engl. (Passifloraceae) IJPSR, 2013; Vol. 4(4): 1370-1377.
    • Francis M. Sarpong, T.C. Fleischer , Kofi Annan,  Isaac K. Amponsah, Rita A. Dickson , Merlin LK  Mensah ( 2013). Anti-Inflammatory and Antioxidant Ecdysteroid and Fatty Acids from the Roots of Palisota hirsuta Schum Commelinaceae), IJPP 28 (2),:1159-1165.
    1. C. Fleischer, M.L.K. Mensah, A.Y. Mensah, R.A. Dickson, C. Argyropoulou and H. Skaltsa Chemical composition of essential oils of Chromolaena odorata (L.) R. M. King & h. Rob, Clausena anisata (Willd.) J.d. Hook ex. Benth and Monodora myristica (Gaertn.) Dunal growing in Ghana. IJPSR, 2013; 4(7): 1000-1007.
    • RA Dickson, MLK Mensah, KP Thomford, K Annan, FC Mills-Robertson, AA Appiah, O Quarshie, S Antwi, S Kaminta, D Edoh Quality and safety evaluation of a Ghanaian polyherbal product EAF-2011 for the management of superficial mycoses, Int J Med Biomed Res 2013;2(2):91-102
    • Sam, G.H., Mensah, M.L.K., Annan Kofi and Sena Zahree .Plants Traditionally Used in Treating Malaria, Typhoid Fever and Piles in the Wa Municipality and Wa East (Funsi) District of the Upper West Region of Ghana .2011. Advances in Environmental Biology, 5(10): pages 3352-3358, 2011.
    • Fleischer, JA Sarkodie, G Komlaga, G Kuffour, RA Dickson, MLK. Mensah (2011). Hypoglycaemic and Antioxidant Activities of the Stem Bark of Morinda Lucida Benth in Streptozotocin – Induced Diabetic Rats. Pharmacognosy Communications, 1(2), 2011, 23-29
    • Fleischer, TC, Mensah, AY, Oppong, AB, Mensah, MLK, Dickson, RA, Annan, K Antimicrobial and anti-inflammatory activities of the leaves of Clerodendrum splendens leaves Pharmacognosy Communications, 1(1), 2011, 85-89.
    • Yaw Adusi-Poku, L. K. N. Okine, F. K. Hlortsi-Akakpo, T. C. Fleischer, M. L. K. Mensah, P. Arhin, George Agyemfra, T. Dabra VI, E. N. Mensah (2010) Assessing Medical Herbalists in Professional Qualifying Examination in Ghana, A Model, J. Tradit. Complement. Altern. Med. 7 (1) 85-87
    • Rodolfo J, Acquaye D, Moharram H, Mensah, MLK., Fleischer, T.C., Annan K., Dickson, R. Mensah., A.Y. Quansah, C., Asare, E., Akromah, R., Renaud, E, Wang M,and Simon, J (2008), Intraspecific variation of Lippia multiflora essential oil from Ghana. J Essent Oil Res. 20, 49-55.
    • Yaw Adusi-Poku, Archibald Sittie, Merlin L. K. Mensah, Kwame Sarpong, Theophilus C.Fleischer , Theophilus C. Ankrah and Dominic Nsiah (2008) Effectiveness and safety assessment of mist tonica, a herbal haematinic

    xxiv.        Sam, GH, Mensah, M.L.K. and Nyakoa-Ofori N. (2011) Pharmacognostic Studies and Standardization of Cassia Sieberiana Roots , Phcog. J, 3, (21), 12-17; DOI:10.5530/pj.2011.21.2

    Afr. J. Trad. CAM 5 (2): 115 – 119

    • Fleischer, T.C., Komlaga, G., Mensah, A.Y., Mensah, M.L.K., Woode, E., Sawer, I.K., Grey, A.I. (2006) Flavonoid constituents of the mature fruit of Tetrapleura tetraptera Journal of Science and Technology (Ghana) 26 (1): 41-47.
    • Mensah, A.Y., Houghton, P.J., Agyare, C., Komlaga, G., Mensah, M. L.K., Fleischer, T.C. and Sarpong G (2006) Investigation of activities related to wound healing of Secamone afzelii. Journal of Science and Technology (Ghana) 26 (3): 83-89.
    • Anastasia Karioti, Dimitra Hadjipavlou-Latina, Merlin L.K. Mensah, Theophilus C. Fleischer and Helen Skaltsa (2004) Composition and Antioxidant Activity of the Essential Oils of Xylopia aethiopica (Dun) A. Rich. (Annonaceae) Leaves, Stem Bark, Root Bark and Fresh and Dried Fruits, Growing in Ghana. Agric. Food Chem. 52 (26) 8094 – 8098.
    • Mensah A. Y., Houghton P. J., Akyirem G. N. A., Fleischer, T.C., Mensah M. L. K., Sarpong K. and Adosraku R. (2004) Evaluation of the antioxidant and free radical scavenging properties of Secamone afzelii Rhoem. Phytotherapy Research 18 (12). 1031-1032
    • Boateng SK; Bennett-Lartey, SO; Opoku-Agyeman, MO; Mensah, MLK; and Fleischer, TC. (2004) Ethno-botanical survey of medicinal plants in the Plant Genetic Resources Centre Arboretum-Bunso. J. Nat. Prod. and Med. 08, 5-7
    • Fleischer, T.C., Ameade, E.P.K., Mensah, MLK. and Sawer, I.K. (2003) Antimicrobial activity of the leaves and seeds of Bixa orellana Fitoterapia 74, 136-138
    • Mensah, MLK. (2002), The Role of the Pharmacist in the Use of Herbal Medicines in Ghana. Ghana Pharm. J.25, 35-39
    • Mensah, M.L.K., and Sarpong, K. Improving Plant Drug Yield – A Study of the Hyoscine: Hyoscyamine ratio in a Datura Hybrid. “J.UST 1994 14(2) 68-70
    • Mensah, M.L.K; Sarpong, K.; Baser K.H.C; Ozek., T(1993), “The Essential Oil of Ageratum conyzoides from Ghana “J.Essent. Oil Res. 5 113-115
    • Sarpong, K; Mensah, MLK.; Heymann, H.: “Some Alkaloidal constituents of the Stem Bark of Pachypodanthium staudtii Engl. &Diels.” UST (1990) 9 (No.1) 5-18
    • Evans, W.C.; Grout, R.J.; Mensah, MLK; “Withanolides of Datura spp. and Hybrids” Phytochemistry (1984) 23 1717 – 172
    1. Sarpong, K.; Mensah, MLK; Santra D.K.; “Intraspecific Variability in Cola nitida and Cola acuminata” Gh. Pharm. J. (1975) 93, 115-123

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