Publications
Selected peer-reviewed publications of original articles
1. MUTOCHELUH Mohamed, ANSAH Charles, BUABENG Kwame Ohene, TWUMASI-ANKRAH Sampson et al. A cryptolepis sanguinolenta- based preparation reduced hospital stay and mortality of covid-19 patients during the pandemic. African J Tradit Complement Altern Med., (2025) 21 (1): 1-11. https://doi.org/10.21010/AJTCAMv21i1.1
2. Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Bright S. Addy, Sian Lant, Rebecca P. Sumner, Carlos Maluquer de Motes, Gordon A. Awandare, Charles Ansah, Mohamed Mutocheluh. The Pharmacologically Active Alkaloid Cryptolepine Activates a Type I Interferon Response That Is Independent of MAVS and STING Pathways. Journal of Immunology Research, vol. 2022, Article ID8873536, https://doi.org/10.1155/2022/8873536
3. Oluwatomisin Deborah Afolayan, Caleb Kesse Firempong, Gustav Komlaga, Patrick Addo-Fordjour, Bright Addy, Seth Agyei Domfeh, Patrick Williams Narkwa, Mohamed Mutocheluh, Benjamin Obukowho Emikpe. In vitro cytotoxic activity of five Ghanaian plants on human cancer cell lines. Volume 26, December 2024, e02477; https://doi.org/10.1016/j.sciaf.2024.e02477
4. Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Odalys Rivera, Martin M. Danaah, Baba A.N. Musah, Gordon A. Awandare, Kwesi B. Mensah, Mohamed Mutocheluh. Cryptolepine and Nibima inhibit hepatitis B virus replication. Scientific African 13 (2021) e00942. https://doi.org/10.1016/j.sciaf.2021.e00942
6. Mohamed Mutocheluh and Patrick W. Narkwa. Aflatoxin B1: An Immunomodulator and Cancer Agent. Aflatoxins - Occurrence, Detection and Novel Detoxification Strategies. Edited by Jean Claude Assaf. https://www.intechopen.com/chapters/83715
7. Jonathan Akwasi Adusei, Patrick Williams Narkwa, Michael Owusu, Seth Agyei Domfeh, Mahmood Alhassan, Emmanuel Appau, Alimatu Salam, Mohamed Mutocheluh. Evidence of chikungunya virus infections among febrile patients at three secondary health facilities in the Ashanti and the Bono Regions of Ghana. PLOS Neglected Tropical Diseases | https://doi.org/10.1371/journal.pntd.0009735
8. Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Gordon A. Awandare, Charles Ansah, Alimatu Salam and Mohamed Mutocheluh. Cryptolepine inhibits hepatocellular carcinoma growth through inhibiting interleukin-6/STAT3 signalling.BMC Complementary Medicine and Therapies (2021) 21:161. https://doi.org/10.1186/s12906-021-03326-x
9. Patrick W. Narkwa, Seth A. Domfeh, Gordon Awandare, and Mohamed Mutocheluh. Cryptolepine, a Plant-derived Alkaloid, Differentially Regulates Signal Transduction Pathways in Human Embryonic Kidney (HEK293) Cells. Journal of Science and Technology, Vol. 41, No.3 (2023), pp 38-51. https://dx.doi.org/10.4314/just.v41i3.4
10. Flavia Kaduni Bawa, Mohamed Mutocheluh, Sylvester Donne Dassah, Patrick Ansah, Abraham Rexford Oduro. Genetic diversity of rotavirus infection among young children with diarrhoea in the Kassena-Nankana Districts of Northern Ghana: a seasonal cross-sectional survey. PAMJ -44(148). 28 Mar 2023. https://www.panafrican-med-journal.com//content/article/44/148/full
11. Seth Agyei Domfeh, Samuel Asamoah Sakyi, Enoch Odame Anto, Patrick Williams Narkwa, Mohamed Mutocheluh, Margaret T Frempong. African Journal of Gastroenterology and Hepatology; Jan 2023. 10.21608/AJGH.2023.183024.1025, https://ajgh.journals.ekb.eg/
12. E Akowuah, G Acheampong, NK Ayisi-Boateng, A Amaniampong, FO Agyapong, J Senyo Kamasah, G Agyei, DO Owusu, B Nkrumah, M Mutocheluh et al. Comparable Detection of SARS-CoV-2 in Sputum and Oropharyngeal Swab Samples of Suspected COVID-19 Patients. COVID 2022, 2, 858–866. COVID 2022, 2, 858–866. https://doi.org/10.3390/covid2070062
13. Oliver Nangkuu Deberu, Godfred Acheampong, Bernard Nkrumah, Nana Kwame Ayisi-Boateng, Stephen Opoku Afriyie, Francis Opoku Agyapong, Dorcas Ohui Owusu, Mohamed Mutocheluh, Abass Abdul-Karim, Philip El-Duah, Augustina Angelina Sylverken, Michael Owusu. Microbial Organisms in the Lower Respiratory Tract Associated with SARS-CoV-2 Infection: A Cross-Sectional Study in Northern Ghana. COVID 2023, 3(4), 440-451; https://doi.org/10.3390/covid3040033
14. Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Bright S. Addy, Sian Lant, Rebecca P. Sumner, Carlos Maluquer de Motes, Gordon A. Awandare, Charles Ansah, Mohamed Mutocheluh. The Pharmacologically Active Alkaloid Cryptolepine Activates a Type I Interferon Response That Is Independent of MAVS and STING Pathways. Journal of Immunology Research, vol. 2022, Article ID8873536, https://doi.org/10.1155/2022/8873536
15. Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Odalys Rivera, Martin M. Danaah, Baba A.N. Musah, Gordon A. Awandare, Kwesi B. Mensah, Mohamed Mutocheluh. Cryptolepine and Nibima inhibit hepatitis B virus replication. Scientific African 13 (2021) e00942. https://doi.org/10.1016/j.sciaf.2021.e00942
16. Jonathan Akwasi Adusei, Patrick Williams Narkwa, Michael Owusu, Seth Agyei Domfeh, Mahmood Alhassan, Emmanuel Appau, Alimatu Salam, Mohamed Mutocheluh. Evidence of chikungunya virus infections among febrile patients at three secondary health facilities in the Ashanti and the Bono Regions of Ghana. PLOS Neglected Tropical Diseases | https://doi.org/10.1371/journal.pntd.0009735
17. Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Gordon A. Awandare, Charles Ansah, Alimatu Salam and Mohamed Mutocheluh. Cryptolepine inhibits hepatocellular carcinoma growth through inhibiting interleukin-6/STAT3 signalling.BMC Complementary Medicine and Therapies (2021) 21:161. https://doi.org/10.1186/s12906-021-03326-x
18. Michael Owusu, Augustina Angelina Sylverken, Philip El-Duah, Nana Kwame Ayisi-Boateng, Richmond Yeboah, Mohamed Mutocheluh et al. Low risk of SARS-CoV-2 in blood transfusion. PLOS ONE | https://doi.org/10.1371/journal.pone.0249069
19. Theophilus Quaye, Patrick Williams NarkwaI, Seth A. Domfeh, Gloria Kattah, Mohamed Mutocheluh. Immunosurveillance and molecular detection of hepatitis B virus infection amongst vaccinated children in the West Gonja District in Savanna Region of Ghana. Sept 2021. PLOS ONE https://doi.org/10.1371/journal.pone.0257103
20. Kwabena Dankwa, Samuel Victor Nuvor, Dorcas Obiri-Yeboah, Patrick Kwame Feglo and Mohamed Mutocheluh. Occurrence of Cryptosporidium Infection and Associated Risk Factors among HIV-Infected Patients Attending ART Clinics in the Central Region of Ghana. Trop. Med. Infect. Dis. 2021, 6, 210. https://doi.org/10.3390/tropicalmed6040210
21. Kwabena Dankwa , Patrick K. Feglo, Samuel V. Nuvor, Michael Aggrey-Korsah, and Mohamed Mutocheluh. Cryptosporidium Infection and Associated Risk Factors among Cattle in the Central Region of Ghana. Journal of Parasitology Research. Vol 2021, Article ID 6625117, 8 pages. https://doi.org/10.1155/2021/6625117
22. Elizabeth Tabitha Botchway, Elizabeth Agyare, Letsa Seyram, Kwadwo Koduah Owusu, Mohamed Mutocheluh, Dorcas Obiri-Yeboah. Prevalence and attitude towards hepatitis B vaccination among healthcare workers in a tertiary. PAMJ - 36(244);05 Aug 2020.
23. Kubi JA, Mutocheluh M, Bonney JHK, Ampofo WK, Odoom JK. Molecular detection of enterovirus D68 among children with acute respiratory tract infection in Ghana. Afr J Lab Med. 2019;8(1), a732. https://doi.org/10.4102/ajlm.v8i1.732
24. Boateng R, Mutocheluh M, Dompreh A, Obiri-Yeboah D, Odame Anto E, Owusu M, et al. Sero-prevalence of Hepatitis B and C viral coinfections among HIV-1 infected ART-naïve individuals in Kumasi, Ghana. (2019) PLoS ONE 14(4):e0215377.https://doi.org/10.1371/journal.pone.0215377
25. Dorcas Obiri-Yeboah, Patrick K. Akakpo, Mohamed Mutocheluh, Emmanuel Adjei-Danso, Gloria Allornuvor, Daniel Amoako-Sakyi et al,. Epidemiology of cervical human papillomavirus (HPV) infection and squamous intraepithelial lesions (SIL) among a cohort of HIV-infected and uninfected Ghanaian women. BMC Cancer (2017) 17:688. DOI 10.1186/s12885-017-3682-x
26. Benedict Osei-Tawiah, Theophilus B Kwofie, Mohamed Mutocheluh, Richard Ephaim and Emmanuel Awusah Blay. Prevalence of HIV, Hepatitis B, Hepatitis C and Syphilis Infections among Patients in a Psychiatric Hospital in Ghana. Int J Virol AIDS6:050. doi.org/10.23937/2469-567X/1510050.
27. Mohamed Mutocheluh and Patrick W Narkwa. Aflatoxin B1 Inhibits the Replication of Chandipura Virus in Human Hepatoma Cells. Annals of Microbiology and Immunology. 2018; 1(2):1008.
28. Gilbert Kotei Ashie, Mohamed Mutocheluh, Michael Owusu, Theophilus Benjamine Kwofie, Samuel Akonor, Patrick Williams Narkwa et al. Microbial pathogens associated with acute childhood diarrhoea in Kumasi, Ghana. BMC Research Notes (2017) 10:264. DOI 10.1186/s13104-017-2578-9.
29. Elvis K. Tiburu, Mohamed Mutocheluh, Patrick K. Arthur, Patrick Williams Narkwa, Ali A. Salifu,, Michael Anim Agyei et al. Antifungal and Anti Proliferative Effects of Zeolites A and X on Yeast Pathogenic and Cancer Cells In Vitro. Journal of Biomaterials and Tissue Engineering; vol. 7, 544-555 (2017).
30. Patrick W. Narkwa, David J. Blackbourn and Mohamed Mutocheluh. Aflatoxin B1 inhibits the type 1 interferon response pathway via STAT1 suggesting another mechanism of hepatocellular carcinoma. Narkwa et al. Infectious Agents and Cancer (2017) 12:17.
31. Bernice Ameyaw, Mohamed Mutocheluh, Michael Owusu, Alhassan Abiba Khalifah, Richard Vikpebah Duneeh and Patrick Williams Narkwa. Performance of First Response® and CareStart™ Malaria Rapid Diagnostic Tests for the Detection of Plasmodium falciparum in a Tertiary Hospital in Ghana. British Journal of Medicine & Medical Research19(8): 1-7, 2017; Article no. BJMMR.30892.
32. P. W. Narkwa, M. Mutocheluh, T. B. Kwofie, M. Owusu, A. Annan, I. Ali and J. K. Boamah. Dengue virus exposure among blood donors in Ghana. Journal of Medical and Biomedical Sciences (2016) 5(2): 30-35. doi: http://dx.doi.org/10.4314/jmbs.v5i2.5.
33. M. Mutocheluh, L. Hindle, C. Areste, S.A. Chanas, L.M. Butler, K.Lowry, K. Shah, D.J. Evans and David J. Blackbourn. Kaposi’s Sarcoma- associated herpevirus viral interferon regulatory factor-2 inhibits type 1 interferon signalling by targeting interferon-stimulated gene factor- 3. Journal of General Virology; 2011 October; 92 (Pt 10): 2394-8. Epub 2011 Jun 22.
34. Theophilus B. Kwofie, Michael Owusu, Mohamed Mutocheluh, Samuel Blay Nguah, Joseph Obeng-Baah, Charlotte Hanson and Albert Dompreh. Pattern and predictors of immunologic recovery in HIV infected patients. Biomed Central Research Article. BMC Research Notes (2015)8:413.
35. Cristina Aresté, Mohamed Mutocheluh and David J Blackbourn. Identification of caspase-mediated decay of interferon regulatory factor-3, exploited by a Kaposi’s Sarcoma-associated herpesvirus immunoregulatory protein. Journal of Biological Chemistry; 2009 August 28;284(35):23272-85. Epub 2009 Jun 24.
36. Theophilus B. Kwofie, Frederick Ayensu, Mohamed Mutocheluh, Patrick Narkwa, Samuel B. Nguah, Cornelius A. Turpin, Michael Owusu. Seroprevalence of Rubella Virus, Cytomegalovirus and Herpes Simplex Virus–2 among Pregnant Women at the Komfo Anokye Teaching Hospital, Ghana. Journal of Public Health in Developing Countries; 2015 Nov. Vol. 1, No. 2, pp. 56-63.
37. Theophilus Benjamin Kwofie and Mohamed Mutocheluh. Behavioural Practices Associated with Occurrence of HIV among University Students in Ghana. British Journal of Medicine & Medical Research10(10): 1-11, 2015 Sept, Article no. BJMMR.18827.
BOOK CHAPTER
1. Mohamed Mutocheluh and Patrick W. Narkwa. Aflatoxin B1: An Immunomodulator and Cancer Agent. Aflatoxins - Occurrence, Detection and Novel Detoxification Strategies. Edited by Jean Claude Assaf. https://www.intechopen.com/chapters/83715
REVIEW ARTICLES
1. Y Mubarik, ST Boyetey, AR Aikins, M Mutocheluh. Effect of Ochratoxin A (OTA) on the Immune System: A Systematic Review - Toxins, 2025.Toxins 2025, 17(5), 256; https://doi.org/10.3390/toxins17050256
2. Daniel Ataanya Abera, Christopher Larbie, James Abugri, Mina Ofosu, Mohamed Mutocheluh, Julius Dongsogo. Prevalence and Predictors of Gestational Diabetes Mellitus