Prof. (Mrs.) Linda Ahenkorah Fondjo

Associate Professor


Dept: Molecular Medicine
Department of Molecular Medicine,
School of Medicine and Dentistry,
KNUST

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Research Areas/Interests

Her research interests focuses elucidating pathophysiology and biomarker identification for early prediction and management of conditions af...~more


Publications

     

    Fondjo, L.A., Awuah, E.O., Sakyi, S.A. et al.Association between endothelial nitric oxide synthase (eNOS) gene variants and nitric oxide production in preeclampsia: a case–control study in Ghana. Sci Rep 13, 14740 (2023). https://doi.org/10.1038/s41598-023-41920-w

    Benjamin Ahenkorah, Samuel Asamoah Sakyi, Linda Ahenkorah Fondjo, Gideon Helegbe, Eddie-Williams Owiredu, Edmund Muonir Der, Linda Eva Amoah, Kwadwo Asamoah Kusi, Dorotheah Obiri, Benjamin Amoani, Samuel Bimpong, Winfred Ofosu, Christian Obirikorang, Enoch Odame, Christopher Larbie, Priscilla Arthur-Johnson, Isaac Quaye, Emmanuel Mawuli Ametefe, Bernard Kwaku Okai, Rasheed Anormah, Emmanuel Akorli, Ana Maria Simono Charadan, Robilu Mikdad Aboubacar, Emmanuel Amesewu, Ben Gyan, Evaluating circulating soluble markers of endothelial dysfunction and risk factors associated with PE: A multicentre longitudinal case control study in northern Ghana, Heliyon, Volume 9, Issue 9, 2023,e19096,ISSN 2405-8440,https://doi.org/10.1016/j.heliyon.2023.e19096.

    Danquah, M., Owiredu, W.K.B.A., Eghan Jnr A., .  Dorcas Serwaa, Enoch Odame Anto, Maxwell Owusu Peprah, Christian Obirikorang, Linda Ahenkorah Fondjo Diagnostic value of neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for detection of renal failure in hypertensives: a case–control study in a regional hospital in Ghana. BMC Nephrol 24, 114 (2023). https://doi.org/10.1186/s12882-023-03120-6

     Fondjo, LA, Sarpong, D,  Owiredu, WKBA,  Opoku, S,  Adu-Bonsaffoh, K,  Teviu, E.  Effect of magnesium sulfate treatment on mediators of endothelial dysfunction and electrolytes in mild and severe preeclampsia: a case-control study. Health Sci Rep.  2023; 6:e1232. doi:10.1002/hsr2.1232

     Fondjo LA, Osei O, Owiredu WKBA, Obirikorang C, Senu E, Owusu-Antwi R, Brefo EFJ. (2022). Assessment of vitamin D levels and adipokines mediated obesity among psychiatric patients on treatment and treatment naïve: A comparative cross-sectional study. Health Sci Rep. Oct 7;5(6):e858. doi: 10.1002/hsr2.858. PMID: 36248351; PMCID: PMC9547132.

    Opoku Mensah B, Fondjo LA, Owiredu WKBA, Adusei B. (2022). Urinary PCA3 a Superior Diagnostic Biomarker for Prostate Cancer among Ghanaian Men. Dis Markers. Oct 7; 2022:1686991. doi: 10.1155/2022/1686991. PMID: 36246565; PMCID: PMC9568348.

    Sakyi, S. A., Boateng, A. O., Fondjo, L. A., Mensah, K. Y., Opoku, S., Senu, E., ... & Sampson, J. E. (2022). Polymorphism of protein tyrosine phosphatase non?receptor type 22 and protein arginine deiminase 4 gene among Ghanaian rheumatoid arthritis patients: A case–control study. International Journal of Rheumatic Diseases. https://doi.org/10.1111/1756-185X.14348

    Ahenkorah B, Sakyi SA, Helegbe G, Owiredu E-W, Fondjo LA, Ofosu W, et al. (2022) Foeto-maternal complications associated with low birth weight: A prospective multicenter study in northern Ghana. PLoS ONE 17(4): e0266796. https://doi.org/10.1371/journal.pone.0266796

    Fondjo, L.A., Amoah, B., Annan, J.J. et al.Hematobiochemical variability and predictors of new-onset and persistent postpartum preeclampsia.Sci Rep 12, 3583 (2022). https://doi.org/10.1038/s41598-022-07509-5

    Eric Gyan, William K.B.A. Owiredu, Linda Ahenkorah Fondjo, Andrew M. Jackson, Andrew R. Green, Michael S. Toss, Patrick K. Akakpo, Leonard Derkyi-Kwarteng, Ganiyu A. Rahman, The combination phenotype of B-cell specific Moloney murine leukaemia virus integration site 1 (BMI1) and CD44+/CD24−/low associates with poor clinicopathological features in African patients with breast cancer,Gene Reports, Volume 26, 2022,101475,ISSN 2452-0144,https://doi.org/10.1016/j.genrep.2021.101475.(https://www.sciencedirect.com/science/article/pii/S2452014421004593)

    Gyan E, Owiredu WKBA, Fondjo LA, Jackson AM, Green AR, Rahman GA. A review of the racial heterogeneity of breast cancer stem cells. Gene. 2021 Sep 5;796-797:145805. doi: 10.1016/j.gene.2021.145805. Epub 2021 Jun 29. PMID: 34197949.

    Fondjo LA, Tashie W, Owiredu WKBA, Adu-Gyamfi EA, Seidu L. High prevalence of vitamin D deficiency among normotensive and hypertensive pregnant women in Ghana. BMC Pregnancy Childbirth. 2021 Apr 26;21(1):331. doi: 10.1186/s12884-021-03802-9. PMID: 33902494; PMCID: PMC8077698.

    Samuel Asamoah Sakyi, Maxwell Hubert Antwi, Linda Ahenkorah Fondjo, Edwin Ferguson Laing, Richard K. Dadzie Ephraim, Alexander Kwarteng, Benjamin Amoani, Seth Christopher Appiah, Bright Oppong Afranie, Stephen Opoku, Tonnies Abeku Buckman, "Vitamin D Deficiency Is Common in Ghana despite Abundance of Sunlight: A Multicentre Comparative Cross-Sectional Study", Journal of Nutrition and Metabolism, vol. 2021, ArticleID 9987141, 7 pages, 2021.https://doi.org/10.1155/2021/9987141

    Gyan E, Green A, Ahenkorah-Fondjo L, Jackson A, Toss MS, Akakpo PK, Derkyi-Kwarteng L, Rahman GA, Owiredu W. The role of ALDH1A1 in contributing to breast tumour aggressiveness: A study conducted in an African population. Ann Diagn Pathol. 2021 Apr;51:151696. doi: 10.1016/j.anndiagpath.2020.151696. Epub 2021 Jan 14. PMID: 33460998.

    Michael Frimpong, Louis Kyei-Tuffuor, Linda Ahenkorah Fondjo, Hubert Senanu Ahor, Priscilla Adjei-Kusi, Oumou Maiga-Ascofare, Richard Odame Phillips, Evaluation of a real-time recombinase polymerase amplification assay for rapid detection of Schistosoma haematobium infection in resource-limited setting, Acta Tropica,Volume 216, 2021,105847, ISSN 0001-706X,https://doi.org/10.1016/j.actatropica.2021.105847.(https://www.sciencedirect.com/science/article/pii/S0001706X21000267)

    Worlanyo Tashie, Linda Ahenkorah Fondjo, William K. B. A. Owiredu, Richard K. D. Ephraim, Listowell Asare, Enoch Appiah Adu-Gyamfi, Laila Seidu, "Altered Bioavailability of Nitric Oxide and L-Arginine Is a Key Determinant of Endothelial Dysfunction in Preeclampsia", BioMed Research International, vol. 2020, Article ID 3251956, 9 pages, 2020. https://doi.org/10.1155/2020/3251956

    Enoch Appiah Adu-Gyamfi, Armin Czika, Tai-Hang Liu, Philip Narteh Gorleku, Linda Ahenkorah Fondjo, Francis Tanam Djankpa, Yu-Bin Ding, Ying-Xiong Wang, Ephrin and Eph Receptor Signaling in Female Reproductive Physiology and Pathology,Biology of Reproduction, , ioaa171,https://doi.org/10.1093/biolre/ioaa171

    Samuel Asamoah Sakyi, Anthony Enimil, David Kwabena Adu, Richard Dadzie Ephraim, Kwabena Owusu Danquah, Linda Fondjo, David Baidoe-Ansah, Prince Adoba, Emmanuel Toboh, Bright Oppong Afranie, Individual and combined bioscore model of presepsin, procalcitonin, and high sensitive C - reactive protein as biomarkers for early diagnosis of paediatric sepsis, Heliyon,Volume 6, Issue 9, 2020,e04841,ISSN 2405-8440, https://doi.org/10.1016/j.heliyon.2020.e04841.

    Owusu-Afriyie, O., Owiredu, W.K.B.A., Oti, A.A. Linda Ahenkorah Fondjo et al. Survival rates of head and neck cancers in Ghana: a retrospective study at the Komfo Anokye Teaching Hospital. BMC Res Notes 13, 392 (2020). https://doi.org/10.1186/s13104-020-05233-9

    Fondjo LA, Addai-Mensah O, Annani-Akollor ME, Quarshie JT, Boateng AA, Assafuah SE, et al. (2020) A multicenter study of the prevalence and risk factors of malaria and anemia among pregnant women at first antenatal care visit in Ghana. PLoSONE 15(8):e0238077.https://doi.org/10.1371/journal.pone.0238077

    Eric Gyan, Linda Ahenkorah Fondjo, William Owiredu, Andrew Jackson, Andrew Green, Breast cancer stem cells: A fallow research ground in Africa, Pathology - Research and Practice,Volume 216, Issue 10, 2020,153118, ISSN 0344-0338, https://doi.org/10.1016/j.prp.2020.153118.

    Enoch Odame Anto; W.K.B.A. Owiredu; Eric Adua; Christian Obirikorang; Linda Ahenkorah Fondjo; Max Efui Annani-Akollor; Emmanuel Acheampong; Evans Adu Asamoah; Peter Roberts; Wei Wang; Sampson Donkor, (2020) Prevalence and lifestyle-related risk factors of obesity and unrecognized hypertension among bus drivers in Ghana, Heliyon, ISSN: 2405-8440, Vol: 6, Issue: 1, Page: e03147 https://doi.org/10.1016/j.heliyon.2019.e03147

    Kweku Bedu-Addo, Richard K.D. Ephraim, Comfort Tanoe-Blay, Linda Ahenkorah-Fondjo, Kwame Osei-Darkwah, Mabel Ephraim, Kate A. Kontoh & Albert Abaka-Yawson | Ya?am Kemal Akpak (Reviewing editor)(2020)Prevalence and associated factors of fetal macrosomia in a rural community in Ghana,Cogent Medicine,7:1,DOI: 1080/2331205X.2020.1746602

    Fondjo, L.A., Boamah, V.E., Fierti, A. et al. Knowledge of preeclampsia and its associated factors among pregnant women: a possible link to reduce related adverse outcomes. BMC Pregnancy Childbirth 19, 456 (2019) doi:10.1186/s12884-019-2623-x

    Adu Gyamfi EA, Fondjo LA, OwireduWKBA, et al. The role of adiponectin in placentation and pre-eclampsia. Cell Biochem Funct. 2019;1–12.https://doi.org/10.1002/cbf.3458

    Addai-Mensah O, Annani-Akollor ME, Nsafoah FO, Fondjo LA, Owiredu E-W, Danquah KO, et al. (2019) Effect of poor glycaemic control on plasma levels and activity of protein C, protein S and antithrombin III in type 2 diabetes mellitus. PLoSONE 14(9):e0223171

    Rebecca Peniel Storph, Frank N. Ghartey, Richard K. D. Ephraim, Enoch Mensah, Martin Mornah, Linda Ahenkorah-Fondjo, et al.,. The Effect of Chemotherapy on Clinical, Haematological and Biochemical Profile in Breast Cancer Patients Undergoing Chemotherapy at Cape Coast Teaching Hospital; A Longitudinal Study. Journal of Cancer and Tumor International 9(2): 1-9, 2019.

    Annani-Akollor, M.E.; Addai-Mensah, O.; Fondjo, L.A.; Sallah, L.; Owiredu, E.-W.; Acheampong, E.; Akamugri, S. Predominant Complications of Type 2 Diabetes in Kumasi: A 4-Year Retrospective Cross-Sectional Study at a Teaching Hospital in Ghana. Medicina 2019, 55, 125.

    Otchere Addai-Mensah, Max Efui Annani-Akollor, Linda Ahenkorah Fondjo, et al., “High-Sensitivity C-Reactive Protein: A Potential Ancillary Biomarker for Malaria Diagnosis and Morbidity,” Disease Markers, vol. 2019, Article ID 1408031, 7 pages, 2019. https://doi.org/10.1155/2019/1408031.

    Otchere Addai-Mensah, Max Efui Annani-Akollor, Linda Ahenkorah Fondjo, et al., “Regular Antenatal Attendance and Education Influence the Uptake of Intermittent Preventive Treatment of Malaria in Pregnancy: A Cross-Sectional Study at the University Hospital, Kumasi, Ghana,” Journal of Tropical Medicine, vol. 2018, Article ID 5019215, 8 pages, 2018. https://doi.org/10.1155/2018/5019215.

    Richard K. D. Ephraim, Enoch Odame Anto, Emmanuel Acheampong, Linda Ahenkorah Fondjo,Richmond B. Barnie, Samuel Asamoah Sakyi, Ambrose Asare Fasting salivary glucose levels is not a better measure for identifying diabetes mellitus than serum or capillary blood glucose levels: comparison in a Ghanaian population. Heliyon 5 (2019) e01286.doi: 10.1016/j.heliyon.2019. e01286 https://doi.org/10.1016/j.heliyon.2019.e01286

     Linda Ahenkorah Fondjo, Osei Owusu-Afriyie, Samuel Asamoah Sakyi, et al., “Comparative Assessment of Knowledge, Attitudes, and Practice of Breast Self-Examination among Female Secondary and Tertiary School Students in Ghana,” International Journal of Breast Cancer, vol. 2018, Article ID 7502047, 10 pages, 2018. https://doi.org/10.1155/2018/7502047.

    Richard k. Dadzie Ephraim, Samuel A. Sakyi, Linda   Fondjo, Justice Afrifa, Prince Agyeman and Prince Darko.  Determinants of Isolated Systolic Hypertension among HIV/AIDS on Highly Active Antiretroviral Therapy:  A  Cross  Sectional  Study  in  the  GA  South  Metropolis.  Ann Med Health Sci Res. 2018;8:360-364

    Richard K. D. Ephraim, Emmanuel Acheampong, Swithin M. Swaray, Linda Ahenkorah Fondjo et al., “Developing a Modified Low-Density Lipoprotein (M-LDL-C) Friedewald’s Equation as a Substitute for Direct LDL-C Measure in a Ghanaian Population: A Comparative Study,” Journal of Lipids, vol. 2018, Article ID 7078409, 9 pages, 2018. https://doi.org/10.1155/2018/7078409.

    Odame Anto E, Owiredu WKBA, Sakyi SA, Turpin CA, Ephraim RKD, Fondjo LA, et al. (2018) Adverse pregnancy outcomes and imbalance in angiogenic growth mediators and oxidative stress biomarkers is associated with advanced maternal age births: A prospective cohort study in Ghana. PLoS ONE 13(7): e0200581. https://doi.org/10.1371/journal.pone.0200581

    Yeboah FA, Fondjo LA, Seini MM, Debrah O, Annan BRDT, Tagoe EA, Bawah AT. Association between antenatal booking visit and occurrence of preeclampsia: A Ghanaian study. Edorium J Gynecol Obstet 2018;4:100020G06FY2018.

    Fondjo LA, Owiredu WKBA, Sakyi SA, Obirikorang C, Wilfred D, Ephraim RKD (2018) CKD-EPI is a Better Tool for Detecting Renal Dysfunction in Hypertensive Pregnancy: A Case-Control Study in Ghana. J Vasc Med Surg 6: 361. doi:4172/2329-6925.1000361

    Richard K.D. Ephraim, Richard Mantey, Stephen Atombo, Samuel A. Sakyi, Linda A. Fondjo, Worlanyo Tashie, Hope Agbodzakey, Felix A. Botchway, Bright Amankwaa, Chronic kidney disease in type 2 diabetes mellitus patients: Comparison of KDIGO and KDOQI guidelines, Alexandria Journal of Medicine, Volume 54, Issue 4, 2018, Pages 445-449

     A.Yeboah, M.M.Seini, C.A.Turpin, L.A.Fondjo, O.Debrah, B.R.D.T.Annan, E.A.Tagoe, A.T.Bawah, (2017), Maternal Serum Calcium and Magnesium levels in women presenting with preeclampsia: Case -Control study in Greater Accra and Ashanti Regions of Ghana Int J Med Health Sci. Vol-6;Issue-4

    Fondjo LA, Owiredu WKBA, Sakyi SA, Laing EF, Adotey-Kwofie MA, Anto EO, et al, (2017) Vitamin D status and its association with Insulin resistance among type 2 diabetics: A case-control study in Ghana, PLoS ONE 12(4):e0175388. Htpps://doi.org/10.1371/journal.pone.0175388

    Linda Ahenkorah Fondjo, Samuel Asamoah Sakyi, William K. B. A. Owiredu, Edwin Ferguson Laing, Eddie-Williams Owiredu, Ebenezer Kwesi Awusi, Richard K. D. Ephraim, Osei Sarfo Kantanka (2018), Evaluation of Vitamin D status in Pre- and Postmenopausal Type 2 Diabetic women and its association with Glucose Homoestasis, Biomed Research International vol2018, https://doi.org/10.1155/2108/9369282

    Oksana Debrah, Francis Agyemang-Yeboah, Richard Harry Asmah, Emmanuel Timmy-Donkoh, Mohammed Mustapha Seini, Linda Ahenkorah Fondjo, Nilok Sight and Ellis Owusu-Dabo, SERO-prevalence of herpes simplex virus type 1 and type 2 among women attending routine Cervicare clinics in Ghana, BMC Infectious Diseases201818:378, https://doi.org/10.1186/s12879-018-3288-1

    Samuel Asamoah Sakyi, Kwabena Owusu Danquah, Richard Dadzie Ephraim, Anthony Enimil, Venus Frimpong, Linda Ahenkorah Fondjo et al., “Evaluating the Contribution of Nocardia spp. and Mycobacterium tuberculosis to Pulmonary Infections among HIV and Non-HIV Patients at the Komfo Anokye Teaching Hospital, Ghana,” Canadian Journal of Infectious Diseases and Medical Microbiology, vol. 2018, Article ID 2910198, 7 pages, 2018. https://doi.org/10.1155/2018/2910198.

    Ngala RA, Fondjo LA, Gmagna P, Ghartey FN, Awe MA (2017) Placental peptides metabolism and maternal factors as predictors of risk of gestational diabetes in pregnant women. A case-control study. PLoS ONE 12(7): e0181613. https://doi.org/10.1371/journal.pone.0181613

    Fondjo LA, Owiredu WKBA, Sakyi SA, Laing EF, Adotey-Kwofie MA, Anto EO, et al, (2017) Vitamin D status and its association with Insulin resistance among type 2 diabetics: A case-control study in Ghana, PLoS ONE 12(4):e0175388. Htpps://doi.org/10.1371/journal.pone.0175388

    Fondjo LA, Gyamfi E.A.A., Owiredu W.K.B.A,. Turpin C.A., Mante D.A. Anto E.O, (2016) Maternal serum adiponectin, leptin and adiponectin-leptin ratio as possible biomarkers of preeclampsia, Edorium J Gynecol Obstet 2016;2:41–47

    Owiredu WKBA, Sakyi SA, Anto EO, Turpin CA, Fondjo LA, Ephraim RKD (2016) Interplay Between Angiogenic Factors and Oxidative Stress Biomark­ers in Normal Pregnancy, Gestational Hypertension and Preeclampsia Med J Obstet Gynecol 4(3): 1086.

    Sakyi SA, Owiredu WKBA, Anto EO, Turpin CA, Ephraim RKD, Fondjo LA. (2016) Individual and Combined Diagnostic Accuracy of Biochemical Markers for Detecting Early On-Set Preeclampsia. SOJ Gynecol Obstet Womens Health 2(1): 9.

    Evelyn Jiagge, Joseph Kwaku Oppong, Jessica Bensenhaver, Francis Aitpillah, Kofi Gyan, Ishmael Kyei, Ernest Osei-Bonsu, Ernest Adjei, Michael Ohene-Yeboah, Kathy Toy, Karen Eubanks Jackson, Marian Akpaloo, Dorcas Acheampong, Beatrice Antwi, Faustina Obeng Agyeman, Zainab Alhassan, Linda Ahenkorah Fondjo, Osei Owusu-Afriyie, Robert Newman Brewer, Amma Gyamfuah, Barbara Salem, Timothy Johnson, Max Wicha, Sofia Merajver, Celina Kleer, Judy Pang, Emmanuel Amankwaa-Frempong, Azadeh Stark, Francis Abantanga, Lisa Newman, Baffour Awuah, (2016) Breast Cancer and African Ancestry: Lessons Learned at the 10-Year Anniversary of the Ghana-Michigan Research Partnership and International Breast Registry, Journal of Global Oncology, doi: 10.1200/JGO.2015.002881.

    Proctor E., Kidwell K.M., Jiagge E., Bensenhaver J., Awuah B., Gyan K., Toy K., Oppong J. K., Kyei I., Aitpillah F., Osei-Bonsu E., Adjei, E., Ohene-Yeboah M., Brewer R.M., Fondjo L. A., Owusu-Afriyie O, Wicha M., Merajver S., Kleer C., Newman L., (2015) Characterizing Breast Cancer in a Population with Increased Prevalence of Triple-Negative Breast Cancer: Androgen Receptor and ALDH1 Expression in Ghanaian Women Ann Surg Oncol. DOI 10.1245/s10434-015-4455

    Obirikorang C., Fondjo, L. A., Adomako S., Bio F.Y., Acheampong I., (2015) Iron Deficiency among pregnant women attending antenatal clinic at the KNUST Hospital, Kumasi, Ghana. British Journal of Medicine & Medical Research 6(8): 823-832.

     W.K.B.A. Owiredu, L. Ahenkorah, N. Amidu, C. A. Turpin, E. F. Laing (2012) Putative risk factors of pregnancy-induced hypertension among Ghanaian pregnant women. Journal of Medical and Biomedical Sciences 1(3): 62-76

    W. K.B.A. Owiredu, L. Ahenkorah, N. Amidu, C. A. Turpin, E. F. Laing, (2010). Seasonal variation in the occurrence of Pregnancy-Induced Hypertension- A Ghanaian study. Journal of Ghana Science Association.,12(1):48-58.

    K.D. Ephraim, W.K.B.A. Owiredu, E.F. Laing, N. Amidu, B.A. Eghan Jnr., Ahenkorah L. (2008). Anaemia as a risk factor for cardiovascular disease in chronic kidney disease. J.Med.Sci.,8(8):707-714.

    Ahenkorah, W. K.B.A. Owiredu, E. F. Laing, N. Amidu, C. A. Turpin (2008). Lipid Profile and Lipid Peroxidation among Ghanaian Pregnancy-Induced Hypertensives J.Med.Sci.,8(8):691-698.

    Turpin C.A., Ahenkorah L., Owiredu W.K.B.A., Laing E.F., Amidu N. (2008). The prevalence of the metabolic syndrome among Ghanaian pregnancy-induced hypertensive patients using the WHO and the NCEPIII criteria. J.Med.Sci.,8(5):443-451.

     

     

     

     

     

     

     

     

     


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