Dr. Yaw Ampem Amoako

Senior Lecturer

Dept: Medicine
Department of Medicine
School of Medical Sciences
Kwame Nkrumah University of Science and Technology
Ward D4,Komfo Anokye Teaching Hospital
Kumasi, Ghana
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Research Areas/Interests

Internal Medicine Infectious Diseases and Tropical Medicine Neglected Tropical Diseases Non Communicable Diseases...~more

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Publications

     

    1. Ackam N, Akenten CW, Boadi AO, Agbanyo A, Abass KM, Amofa G, ...Amoako YA, Phillips RO. Antimicrobial resistant bacteria isolated from Buruli ulcer lesions in Ghana. PLoS Negl Trop Dis. 2025;19(5):e0013140
    2. The African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa. Lancet. 2025;405(10480):715-24. doi: 10.1016/s0140-6736(24)02846-0.
    3. Agbavor B, Arthur RA, Agbanyo A, Ahiatrogah DK, Akenten CW, Adu-Asiamah C, ...Amoako YA, Phillips RO. Improved protocols for isolation of Mycobacterium ulcerans from clinical samples. BMC Microbiol. 2025;25(1):118. Epub 20250305. doi: 10.1186/s12866-025-03835-6.
    4. Schleenvoigt BT, Holtfreter M, Bohnes T, Okwu DG, Amoako YA, Mischlinger J. Safety and efficacy of praziquantel in pregnant women infected with Schistosoma haematobium. International Journal of Infectious Diseases. 2025;153. doi: 10.1016/j.ijid.2024.107327
    5. Kitson-Mills D, Donkor A, Amoako YA, Kyei KA, Bonsu EBO, Vanderpuye V, et al. Outcomes and Toxicities After Treatment for Men Diagnosed With Localized Prostate Cancer in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis. Advances in Radiation Oncology. 2025;10(1). doi: 10.1016/j.adro.2024.101670
    6. Amoako YA, Oppong MN, Laryea DO, Kyem G, Gyabaah S, Agbanyo A, et al. Burden of scabies in a Ghanaian penitentiary. PLoS One. 2024;19(12):e0312108. Epub 20241206. doi: 10.1371/journal.pone.0312108.
    7. Ackam N, Opoku-Boadi A, Agbavor B, Adjei JK, Agbanyo A, Oppong MN, Wiafe-Akenten C, Sylverken A, Obiri-Danso K, Wansbrough-Jones M, Amoako YA, Phillips RO. Bacterial diversity in Buruli ulcer lesions in Ghana. J Clin Tuberc Other Mycobact Dis. 2024;36:100468
    8. Okyere D, Ocloo EK, Owusu L, Amoako YA, Tuwor RD, Koka E, et al. Improving experiences of neglected tropical diseases of the skin: Mixed methods formative research for development of a complex intervention in Atwima Mponua District, Ghana. PLOS Glob Public Health. 2024;4(6):e0002833
    9. Tuwor RD, Mtuy TB, Amoako YA, Owusu L, Oppong MN, Agbanyo A, et al. Stigma experiences, effects and coping among individuals affected by Buruli ulcer and yaws in Ghana. PLoS Negl Trop Dis. 2024;18(4):e0012093
    10. Cano M, Ruiz-Postigo JA, Macharia P, Ampem Amoako Y, Odame Phillips R, Kinyeru E, et al. Evaluating the World Health Organization’s SkinNTDs App as a Training Tool for Skin Neglected Tropical Diseases in Ghana and Kenya: Cross-Sectional Study. J Med Internet Res. 2024;26:e51628
    11. Agbanyo A, Agbavor B, Gyabaah S, Oppong MN, Dornu O, Antwi PB, …Amoako YA, et al. Implementation of an integrated control programme for neglected tropical diseases of the skin in Ghana: The essential role of the laboratory. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. 2024;35:100442.
    12. Amoako YA, Laryea DO, Agbanyo A, Agbavor B, Oppong MN, Kyem G, et al. Prevalence and determinants of impetigo in Ghana: a cross-sectional study. BMC Infectious Diseases. 2024;24(1):349
    13. Yeboah R, Gorman R, Acheampong HK, Nyarko-Afriyie E, Aryeetey S, Tetteh HD, …Amoako YA, et al. Clinical epidemiology, determinants, and outcomes of viral encephalitis in Ghana; a cross-sectional study. PLoS One. 2024;19(2):e0297277
    14. Phillips RO, Owusu L, Koka E, Ocloo EK, Simpson H, Agbanyo A, …Amoako YA, et al. Development of an integrated and decentralised skin health strategy to improve experiences of skin neglected tropical diseases and other skin conditions in Atwima Mponua District, Ghana. PLOS Glob Public Health. 2024;4(1):e0002809
    15. Agbavor B, Agbanyo A, Loglo AD, Antwi PB, Ackam N, Adjei J, …Amoako YA, et al. Clinical and microbiological predictors of healing in Buruli ulcer disease. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. 2024;34:100415
    16. Adjei JK, Aniagyei W, Adankwah E, Seyfarth J, Mayatepek E, Berko DA, …Amoako YA, et al. Memory B-cells are enriched in the blood of patients with acute Buruli ulcer disease: a prospective observational study. BMC Infectious Diseases. 2023;23(1):393
    17. Owusu L, Tuwor RD, Ackam N, Loglo A, Agbavor B, Agbanyo A, …Amoako YA, et al. Role and capacity needs of community-based surveillance volunteers in the integrated management of skin neglected tropical diseases (skin NTDs): a qualitative study from central Ghana. BMC Public Health. 2023;23(1):1086
    18. Amoako YA, van Rietschoten LS, Oppong MN, Amoako KO, Abass KM, Anim BA, et al. Beliefs, attitudes and practices towards scabies in central Ghana. PLoS Negl Trop Dis. 2023;17(2):e0011175.
    19. Akuffo RA, Sanchez C, Amanor I, Amedior JS, Kotey NK, Anto F, …Amoako YA, et al. Endemic infectious cutaneous ulcers syndrome in the Oti Region of Ghana: Study of cutaneous leishmaniasis, yaws and Haemophilus ducreyi cutaneous ulcers. PLoS One. 2023;18(9):e0292034
    20. Amoako YA, van Eyssen A, Brink A. [123I]-metaiodobenzylguanidine imaging findings and outcome in patients with metastatic neuroblastoma. South African Journal of Oncology; Vol 7 (2023)DO - 104102/sajov7i0250. 2023.
    21. Frej A, Cano M, Ruiz-Postigo JA, Macharia P, Phillips RO, Amoako YA, et al. Assessing the Quality of the World Health Organization's Skin NTDs App as a Training Tool in Ghana and Kenya: Protocol for a Cross-sectional Study. JMIR Res Protoc. 2022;11(12):e39393
    22. El-Duah P, Sylverken AA, Owusu M, Amoako YA, Yeboah R, Gorman R, et al. Genetic characterization of varicella-zoster and HIV-1 viruses from the cerebrospinal fluid of a co-infected encephalitic patient, Ghana. Virology Journal. 2022;19(1):122
    23. Mudji J, Ackam N, Amoako YA, Madinga B, Mumbere P, Agbanyo A, Blum J, Phillips RO, Molyneux DH. Mental distress and health-related quality of life in gambiense human African trypanosomiasis: a case-control study in the Democratic Republic of Congo. Trans R Soc Trop Med Hyg. 2022 Apr 26:trac035. doi: 10.1093/trstmh/trac035. Epub ahead of print. PMID: 35474014.
    24. Abidha CA, Amoako YA, Nyamekye RK, Bedu-Addo G, Grziwotz F, Mockenhaupt FP, et al. Fasting blood glucose in a Ghanaian adult is causally affected by malaria parasite load: a mechanistic case study using convergent cross mapping. Malar J. 2022;21(1):93
    25. Iris Mosweu, Catherine Pitt, Lucy Owusu, Jacob Novignon, Yohannes Hailemichael, Michael Marks, Yaw Amoako, Sergio TorresRueda, Michelle Zavila. Economic evaluations of interventions for neglected tropical diseases of the skin: protocol for a systematic review. PROSPERO 2022 CRD42022350844 From: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022350844
    26. Amoako YA, El-Duah P, Sylverken AA, Owusu M, Yeboah R, Gorman R, Adade T, Bonney J, Tasiame W, Nyarko-Jectey K, Binger T, Corman VM, Drosten C, Phillips RO. Rabies is still a fatal but neglected disease: a case report. J Med Case Rep. 2021 Dec 1;15(1):575. doi: 10.1186/s13256-021-03164-y
    27. Sarkodie B, Asiedu-Bekoe F, Laryea DO, Ampofo WK, Phillips RO, Samba A,…Amoako YA, et al. Overview of preparedness and response to COVID-19 in Ghana. Ghana Medical Journal. 2021;55(2):38-47
    28. Amoako YA, Ackam N, Omuojine JP, Oppong MN, Owusu-Ansah AG, Boateng H, et al. Mental health and quality of life burden in Buruli ulcer disease patients in Ghana. Infect Dis Poverty. 2021;10(1):109
    29. Amoako YA, Ackam N, Omuojine JP, Oppong MN, Owusu-Ansah AG, Abass MK, et al. Caregiver burden in Buruli ulcer disease: Evidence from Ghana. PLoS neglected tropical diseases. 2021;15(6):e0009454.
    30. Amoako YA, Loglo AD, Frimpong M, Agbavor B, Abass MK, Amofa G, et al. Co-infection of HIV in patients with Buruli ulcer disease in Central Ghana. BMC infectious diseases. 2021;21(1):331. Epub 2021/04/10. doi: 10.1186/s12879-021-06009-7
    31. Frimpong M, Amoako Y, Anim K, Ahor H, Ye-Boah R, Arthur J, et al. Diagnostics for COVID-19: A case for field-deployable, rapid molecular tests for community surveillance. Ghana medical journal. 2020;54:71-6. doi: 10.4314/gmj.v54i4s.11.
    32. Amoako YA, Phillips RO, Arthur J, et al. A scabies outbreak in the North East Region of Ghana: The necessity for prompt intervention. PLoS neglected tropical diseases. 2020;14(12):e0008902
    33. Sylverken AA, El-Duah P, Owusu M, Schneider J, Yeboah R, Ayisi-Boateng NK,…Amoako YA, et al. Transmission of SARS-CoV-2 in northern Ghana: insights from whole-genome sequencing. Archives of virology. 2021:1-9. Epub 2021/03/17. doi: 10.1007/s00705-021-04986-3
    34. Ofori-Amoah J, Ofori Addai S, Ampratwum O, Rockson Adjei M, Asare G, Adu Mensah J, et al. Scabies outbreak investigation and treatment in the Sekyere East District, Ghana: A call to end the neglect. Cogent Medicine. 2021;8(1):1964185
    35. Hammond ENB, Amoako YA, Laryea DO, Amoah G. Prostate-specific antigen for prediction of skeletal metastases on bone scintigraphy in prostate cancer. World J Nucl Med. 2021;20(3):327-8.
    36. Sylverken AA, Owusu M, Yeboah R, El-Duah P, Gorman R, Bonney JK, Aryeetey S, Adu E, Amoako YA, Adade T, Yeboah E, et al. Influenza outbreak among students in Ghana: a report from three time points. Influenza outbreak among students in Ghana: a report from three time points. 2020. Research square preprint. DOI: 21203/rs.3.rs-34837/v3
    37. COVIDSurg Collaborative, GlobalSurg Collaborative. SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021 Sep 27;108(9):1056-1063. doi: 10.1093/bjs/znab101
    38. Phillips RO, Robert J, Abass KM, Thompson W, Sarfo FS, Wilson T, et al. Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial. Lancet (London, England). 2020;395(10232):1259-67. Epub 2020/03/17. doi: 10.1016/s0140-6736(20)30047-7
    39. COVIDSurg Collaborative; GlobalSurg Collaborative. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia. 2021 Nov;76(11):1454-1464. doi: 10.1111/anae.15560
    40. COVIDSurg Collaborative; GlobalSurg Collaborative. SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia. 2022 Jan;77(1):28-39. doi: 10.1111/anae.15563. 
    41. COVIDSurg Collaborative; GlobalSurg Collaborative. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021 Jun;76(6):748-758. doi: 10.1111/anae.15458
    42. Collinson S, Frimpong VNB, Agbavor B,…Amoako YA, et al. Barriers to Buruli ulcer treatment completion in the Ashanti and Central Regions, Ghana. PLoS Negl Trop Dis. 2020;14(5):e0008369. Published 2020 May 26. doi:10.1371/journal.pntd.0008369
    43. Graßmann, S.; Pivovarova-Ramich, O.; Henze, A.; Raila, J.; Ampem Amoako, Y.; King Nyamekye, R.; Bedu-Addo, G.; Mockenhaupt, F.P.; Schulze, M.B.; Danquah, I. SNP rs6564851 in the BCO1 Gene Is Associated with Varying Provitamin a Plasma Concentrations but Not with Retinol Concentrations among Adolescents from Rural Ghana. Nutrients2020, 12, 1786.
    44. Amoako YA, Frimpong M, Awuah DO, et al. Providing insight into the incubation period of Mycobacterium ulcerans disease: two case reports. Journal of medical case reports. 2019;13(1):218.
    45. Frimpong M, Agbavor B, Duah MS, et al. Paradoxical reactions in Buruli ulcer after initiation of antibiotic therapy: Relationship to bacterial load. PLoS neglected tropical diseases. 2019;13(8):e0007689.
    46. Amoako YA, Awuah B, Larsen-Reindorf R, et al. Malignant tumours in urban Ghana: evidence from the city of Kumasi. BMC cancer. 2019;19(1):267.
    47. Amoako YA, Hammond ENB, Assasie-Gyimah A, Laryea DO, Ankrah A, Amoah G. Prostate-specific antigen and risk of bone metastases in west Africans with prostate cancer. World journal of nuclear medicine. 2019;18(2):143.
    48. Amoako YA, Hammond EN, Assasie-Gyimah A, Sarfo-Kantanka O. Thyroid scintigraphy in the management of benign thyroid disease. Ghana medical journal. 2018;52(4):242-248.
    49. Amoako YA, Laryea DO, Bedu-Addo G, Andoh H, Awuku YA. Clinical and demographic characteristics of chronic kidney disease patients in a tertiary facility in Ghana. The Pan African medical journal. 2014;18:274.
    50. Amoako YA, Laryea DO, Bedu-Addo G, Nkum BC, Plange-Rhule J. Left ventricular hypertrophy among chronic kidney disease patients in Ghana. Pan African Medical Journal. 2017;28:79.
    51. Bedu-Addo G, Ampem Amoako Y, Bates I. The role of bone marrow aspirate and trephine samples in haematological diagnoses in patients referred to a teaching hospital in Ghana. Ghana medical journal. 2013;47(2):74-78.
    52. Beissner M, Symank D, Phillips RO, et al. Detection of viable Mycobacterium ulcerans in clinical samples by a novel combined 16S rRNA reverse transcriptase/IS2404 real-time qPCR assay. PLoS neglected tropical diseases. 2012;6(8):e1756.
    53. Danquah I, Bedu-Addo G, Terpe KJ, et al. Diabetes mellitus type 2 in urban Ghana: characteristics and associated factors. BMC public health. 2012;12:210.
    54. Danquah I, Dobrucky CL, Frank LK, et al. Vitamin A: potential misclassification of vitamin A status among patients with type 2 diabetes and hypertension in urban Ghana. The American journal of clinical nutrition. 2015;102(1):207-214.
    55. Awittor FK, Amoako YA, Awuah B, Paintsil V, Osei-Tutu L, Laryea DO. A 4-Year Retrospective Analysis of Childhood Cancers in Kumasi, 2012-2015. Ghana Wkly Epidemiol Rep. 2018;3(2):5–10.
    56. Abubakar S, Amoako YA, Kotze T, Tag N. Source of Ectopic ACTH Secretion Easily Identified by 68 Ga DOTANOC PET/CT. Clinical nuclear medicine. 2017;42(4):295-296.
    57. Abubakar SO, Amoako YA, Tag N, Kotze T. False-positive prostate cancer bone metastases on magnetic resonance imaging correctly classified on gallium-68-prostate-specific membrane antigen positron emission tomography computed tomography. World journal of nuclear medicine. 2018;17(4):305.
    58. Amoako YA, Bedu-Addo G. Hyper-reactive malarial splenomegaly (HMS) in a patient with beta thalassaemia syndrome. The Pan African medical journal. 2014;19:310.
    59. Akinyemiju T, Abera S, Ahmed M, et al. The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: Results From the Global Burden of Disease Study 2015. JAMA oncology. 2017.
    60. Laryea DO, Awuah B, Amoako YA, et al. Cancer incidence in Ghana, 2012: evidence from a population-based cancer registry. BMC cancer. 2014;14:362.
    61. Phillips RO, Frimpong M, Sarfo FS, et al. Infection with Mansonella perstans Nematodes in Buruli Ulcer Patients, Ghana. Emerging infectious diseases. 2014;20(6):1000-1003.
    62. Phillips RO, Phanzu DM, Beissner M, et al. Effectiveness of routine BCG vaccination on buruli ulcer disease: a case-control study in the Democratic Republic of Congo, Ghana and Togo. PLoS neglected tropical diseases. 2015;9(1):e3457.
    63. Phillips RO, Sarfo FS, Abass MK, et al. Clinical and bacteriological efficacy of rifampin-streptomycin combination for two weeks followed by rifampin and clarithromycin for six weeks for treatment of Mycobacterium ulcerans disease. Antimicrobial agents and chemotherapy. 2014;58(2):1161-1166.
    64. Phillips RO, Sarfo FS, Abass MK, et al. Reply to "compliance with antimicrobial therapy for buruli ulcer". Antimicrobial agents and chemotherapy. 2014;58(10):6341.
    65. Sarfo FS, Le Chevalier F, Aka N, et al. Mycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring. PLoS neglected tropical diseases. 2011;5(7):e1237.
    66. Sarfo FS, Phillips RO, Zhang J, et al. Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease. BMC infectious diseases. 2014;14:202.
    67. Fitzmaurice C, Allen C, Barber RM, et al. Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015: A Systematic Analysis for the Global Burden of Disease Study. JAMA oncology. 2017;3(4):524-548.
    68. Hammond ENB, Amoako YA, Vangu MWH. Oral lithium as an adjunctive therapy during radioiodine treatment for hyperthyroidism. Nuclear medicine communications. 2017;38(12):1133.
    69. Kollie K, Amoako YA, Ake J, et al. Buruli ulcer in Liberia, 2012. Emerging infectious diseases. 2014;20(3):494-496.
    70. Laryea DO, Amoako Y, Armooh DV, Abbeyquaye EP, Amartey BN. The Threat of Ebola Virus Disease: a Call to Integrate all Sectors in Surveillance Activities in Ghana. Online journal of public health informatics. 2015;7(1).
    71. Laryea DO, Amoako YA, Asamoah J. Antibiotic Sensitivity and Clinical Outcome for Methicillin Resistant Staphylococcus Aureus. Online journal of public health informatics. 2014;6(1).
    72. Laryea DO, Amoako YA, Spangenberg K, Frimpong E, Kyei-Ansong J. Contraceptive use and unmet need for family planning among HIV positive women on antiretroviral therapy in Kumasi, Ghana. BMC women's health. 2014;14:126.
    73. Laryea DO, Ankobeah F, Morhe ESK, Amoako YA, Spangenberg K. Characteristics and contributory factors for injectable contraceptive usage among women in Kumasi, Ghana. Contracept Reprod Med. 2016;1:8.
    74. Laryea DO, Awuah B, Amoako YA, Mensah S, Awittor FK. Follow-up of Breast Cancer Patients in Ghana: Challenges to Community-based Surveillance. Online journal of public health informatics. 2015;7(1).
    75. Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015. Lancet (London, England). 2017;390(10091):231-266.
    76. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet (London, England). 2017;390(10100):1345-1422.
    77. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet (London, England). 2017;390(10100):1260-1344.
    78. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet (London, England). 2017;390(10100):1211-1259.
    79. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet (London, England). 2017;390(10100):1084-1150.
    80. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet (London, England). 2017;390(10100):1151-1210.
    81. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet Respiratory medicine. 2017;5(9):691-706.
    82. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Infectious diseases. 2018.
    83. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet (London, England). 2018;392(10152):1015-1035.
    84. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet (London, England). 2018;391(10136):2236-2271.
    85. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet (London, England). 2018;392(10159):1859-1922.

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