1. 1. May 1995 -June 1997- Trial physician- Kintampo Vitamin A Project (EPI+)
2. 2. November 1996-January 1999 (Head of field work) Trial of the safety, effectiveness and benefits of alternative strategies for the Vitamin A supplementation of young infants and lactating mothers.
3. 3. April 1999-October 1999 Trial physician -Zinc against Plasmodium Study
4. 4. March 2000-April2000 Trial physician International Study of Allergies and Asthma in Children (ISAAC Study)
5. 5. 1997- 2006 Efficacy of “Sprinkles” (ferrous fumarate) to treat anaemia and bioavailability of iron and zinc from sprinkles. (Sprinkles studies).
6. June 2004- December 2005 Principal investigator Assessment of serological responses to Hepatitis B and Haemophilus influenza b vaccines in infants receiving vitamin A supplementation.
7. June 2003-January 2005. Trial physician. Patterns and characterisation of Plasmodium falciparum infections, and morbidity in the Kintampo District of Ghana .
8. May 2004 -June 2006. Local safety monitor A non inferiority, randomised trial of the efficacy and safety of artesunate-amodiaquine, artemether-lumefantrine and artesunate-lapdap for treatment of uncomplicated P falciparum malaria among children in Ghana.
9. November 2006- 2009. Trial physician. A multicenter, randomised double blind double dummy study comparing the efficacy and safety of chlorproguanil-dapsone-artesunate (CDA) versus artemether lumefantrine in the treatment of acute uncomplicated plasmodium falciparum malaria in children and adolescents in Africa.
10. November 2007 –2010 Local Safety Monitor RTS, S AS01E Malaria Vaccine Trial “A Phase II randomised open controlled study of the safety and immunogenicity of GlaxoSmithKline Biologicals candidate RTS, S AS01E, when incorporated into an Expanded Programme on Immunization (EPI) regimen that includes DTPwHep B/Hib, OPV measles and yellow fever vaccinations in malaria endemic regions.
11. October 2007- June 2008. WHO guidelines for feeding Low birth weight infants. Multi center study of feasibility, requirements and effect of their implementation in health facilities.
12. June 2009-November 2012. Co-Principal investigator for Efficacy of newborn vitamin A supplementation in improving child survival in rural Ghana: generation of evidence necessary for informing global policy.
13. January 2010- November 2012. Co Principal Investigator. The Oxytocin Initiative: Determining the effect of prophylactic administration of oxytocin in Uniject™ on postpartum hemorrhage at the community level in four districts in Ghana
14. December 2018-Date. Principal Investigator. A multi-country randomized clinical trial to evaluate the impact of continuous KMC initiated immediately after birth compared to KMC initiated after stabilization in newborns with birth weight 1.0 to1.8 kg on their survival in low-resource settings.
15. October 2019-Date Principal Investigator-The follow-up study to evaluate the impact of continuous KMC initiated immediately after birth compared to KMC initiated after stabilization in newborns with birth weight 1.0 to <1.8 kg on their neurodevelopmental outcomes in low-resource settings-
16. January 2020-date Principal Investigator: Adverse Outcomes in Pregnancy Trial (AdOPT) Africa Study

Publications:

1. 1. Zinc against plasmodium study group. Effect of zinc on the treatment of Plasmodium falciparum malaria in children: a randomized controlled trial. Am J Clin Nutr 2002;76;805-12
2. Tondeur M, Schauer C, Christofides A Kwaku P. Poku, Samuel Newton, Robert Serfass and S Zlotkin Determination of Iron absorption from intrinsically labeled microencapsulated ferrous fumarate (sprinkles) in infants with different hematologic status using a dual stable isotope method. Am J Clin Nutr 2004; 80;1436-44
3. Dugan C et al and the Zinc against plasmodium study group. Plasma zinc Concentrations are depressed during the acute phase response in children with Falciparum Malaria. J Nutr 2005; 135:802-807,
4. Harold C. Furr, Michael Green, Marjorie Haskell, Najat Mokhtar, Penelope Nestel, Sam Newton, Judy Ribaya-Mercado, Guangwen Tang, Sherry Tanumihardjo, Emorn Wasantwisut Stable Isotope Dilution Techniques for Assessing Vitamin A Status and Bioefficacy of Provitamin A Carotenoids in Humans Public Health Nutrition 2005; 8 (6) : 596-607
5. 5. Sam Newton, Simon Cousens, Seth Owusu- Agyei, Suzanne Filteau, Carolynne Stanley, Louise Linsell, betty Kirkwood. Vitamin A Supplementation does not affect infants’ Immune responses to Polio and Tetanus vaccines. J Nutr 2005; 135 2669-2673
6. Samuel K Tchum, Sherrry Tanumihardjo, Sam Newton, Bruno de Benoist, Seth Owusu-Agyei, Fareed K.N Arthur, Tetteh Antonia. Evaluation of vitamin A supplementation regimens in Ghanaian post partum mothers with the use of the relative dose response tests. Am J Clin Nutr 2006:84:1344-9.
7. 7. Stanley H Zlotkin, Claudia Schauer, Seth Owusu-Agyei, Julian Wolfson, Kwaku Poku Asante, Samuel Newton, Robert Serfass. Demonstrating zinc and iron bioavailability from intrinsically labeled microencapsulated ferrous fumarate. J Nutr. 2006 136:920-925.
8. 8. Sam Newton, Seth Owusu-Agyei, William Ampofo, Charles Zandoh, Martin Adjuik, George Adjei G, Samuel Tchum, Suzanne Filteau, Betty R Kirkwood. Vitamin A Supplementation Enhances Infants' Immune Responses to Hepatitis B Vaccine but Does Not Affect Responses to Haemophilus influenzae Type b Vaccine. J Nutr. 2007 May;137(5):1272-7.
9. 9. Sam Newton and John Appiah Poku, Perspectives of researchers on obtaining informed consent in developing countries. Developing World Bioethics.2007 April (1) 19-24
10. 10. Sam Newton and John Appiah Poku J, Opinion of researchers based in the UK on recruiting subjects from developing countries into randomized controlled trials. Developing World Bioethics 2007, Dec (3) 149-156.
11. Newton S, Owusu Agyei S. Need to worry. Wrong vitamin A doses reported. Vaccine 2007 Vol. 25 (23)
12. Newton S, Owusu-Agyei S, Kirkwood B. Is there any monitoring of the quality of capsules used in supplementation programmes. Am J Clin Nutr 2007:86 (4):1254.
13. Newton S, Owusu-Agyei S, Filteau S, Gyan T, Kirkwood BR. Vitamin A supplements are well tolerated with the pentavalent vaccine. Vaccine 2008 (26) 6608-6613.
14. Newton S, Doku V, Geissler W, Asante KP, Cousens S. Drawing blood from young children: lessons learned from a trial in Ghana TRSTM 2009 103 497-499
15. Tchum SK, Newton S, Tanumihardjo SA, Fareed KNA, Owusu-Agyei S. Evaluation of a green leafy vegetable intervention in Ghanaian postpartum mothers. AJFAND 2009, (9) 1294-1308
16. Newton S, Filteau S, Owusu-Agyei S, Ampofo W, Kirkwood BR. Sero protection associated with infant vitamin A supplementation is not related to antibody affinity to Hepatitis B and Haemophilus influenzae type b vaccines. (Vaccine 28 (2010) 4738-4741
17. Owusu-Agyei S, Asante KP, Adjuik M, Adjei G, Awini E, Adams M, Newton S, Greenwood B, Chandramohan D. Epidemiology of malaria in the forest savannah transitional zone of Ghana. Malar J 2009, Sept 28:8:220.
18. Appiah Poku J, Newton S, Kass N. Participants’ perceptions of research benefits in an African genetic epidemiology study, Developing World Bioethics 2011, (11) 128-135.
19. Abdulai M, Baiden F, Adjei G, Afari Asiedu S, Adjei K, Tawiah C, Newton S. An assessment of the likely acceptability of vaginal microbicides for HIV prevention among women in rural Ghana. BMC Women’s Health 2012, 12-40.
20. Adu-Gyasi D, Adams M, Amoako S, Mahama E, Nsoh M, Amenga-Etego S,Baiden F, Asante KP, Newton S, Owusu-Agyei S

21. Estimating malaria parasite density: assumed white blood cell count of 10,000/μl of blood is appropriate measure in Central Ghana.  Malaria Journal 2012, 11:23

22.Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial NEOVITA Study Author Group, Bahl R, Bhandari N, Dube B, Edmond K, Fawzi W,

Fontaine O, Kaur J, Kirkwood BR, Martines J, Masanja H, Mazumder S, Msham S, Newton S, Oleary M, Ruben J, Shannon C,Smith E, Taneja S Yoshida S, Trials 2012, 13:22

23. Stanton, C, Newton S, Mullany LC, Cofie P, Tawiah Agyemang C, Adiibokah E, Niamh D, Khan S, Levisay A, Gyapong J, Armbruster D, Owusu-Agyei S. Impact on postpartum hemorrhage of prophylactic administration of oxytocin 10 IU via UnijectTM by peripheral health care providers at home births: design of a community-based cluster-randomized trial. BMC Pregnancy and Childbirth 2012, 12:42

24. Oboahen O, Owusu-Agyei S, Gyabaa Febir L, Tawiah C, Tawiah T, Afari S Newton S

Community perception and beliefs about blood draw for clinical research in Ghana. Transactions of the Royal Society of Tropical Medicine and Hygiene 2013, 107 (4) 261-5.

25. Humphries D, Simms BT, Davey D, Otchere J, Quagraine J, Terryah S, Newton S, Berg E, Harrison L, Boakye D, Wilson M, Cappello M, Hookworm Infection among School Age Children in Kintampo North Municipality, Ghana: Nutritional Risk Factors and Response to Albendazole Treatment. Am J Trop Med Hyg 2013, 12-0605.

26 Zlotkin S, Newton S, Aimone AA, Azindow I, Amenga-Etego  S Tchum K; Mahama E, Thorpe KE; Owusu-Agyei S  Effect of Iron Fortification on Malaria Incidence in Infants and Young Children in Ghana A Randomized Trial JAMA 2013, 310, 938-94

27. Stanton CK, Newton S, Mullany LC, Cofie P, Agyemang CT, Adiibokah E, Amenga Etego S, Darcy N, Khan S, Armbruster D, Gyapong J, Owusu Agyei S. Effect on Post partum hemorrhage of prophylactic Oxytocin (10 I.U) by injection by Community Health Officers in Ghana: A Community –Based Cluster-Randomised Trial. Plos Medicine, 2013, 1

28Owusu Agyei S, Newton S, Mahama E, Gyabaa Febir L, Ali M, Adjei K, Tchum K, Alhassan L, Moleah T, Tanumihardjo S. Impact of vitamin A with zinc supplementation on malaria morbidity in Ghana. Nutrition Journal 2013, 12, 131

29. van Middendorp DV, Asbroek AA, Bio FY, Edusei A, Meijer L, Newton S, Agyemang C. Rural Urban differences in blood pressure and pregnancy induced hypertension among pregnant women in Ghana. Globalization and Health, 2013, 9, 59.

30.Luke C Mullany, Sam Newton, Samuel Afari-Asiedu, Edward Adiibokah, Charlotte T Agyemang, Patience Cofie, Steve Brooke, Seth Owusu-Agyei, Cynthia K Stanton Cumulative effects of heat exposure and storage conditions of Oxytocin in Uniject in rural Ghana: implications for scale up, Global Health Science and Practice, 2014, Jul 10;2(3):285-94=

31. Lopez-Teros V, Chileshe J, Idohou-Dossou N, Fajarwati T, Medoua Nama G, Newton S, Vinod Kumar M, Wang Z, Wasantwisut E, Hunt JR. International experiences in assessing vitamin A status and applying the vitamin A-labeled isotope dilution method. Int J Vitam Nutr Res. 2014;84 Suppl 1:40-51.

32Karen M Edmond, Sam Newton, Caitlin Shannon, Maureen O’Leary, Lisa Hurt, Gyan Thomas, Seeba Amenga-Etego, Charlotte Tawiah-Agyemang, Lu Gram, Chris N Hurt, Rajiv Bahl, Seth Owusu-Agyei, Betty R Kirkwood. Eff ect of early neonatal vitamin A supplementation on mortality during infancy in Ghana (Neovita): a randomised,double-blind, placebo-controlled trial. Lancet 2014 Dec 10. pii: S0140-6736(14)60880-1.

33.Dennis Adu-Gyasi, Kwaku Poku Asante, Sam Newton, Sabastina Amoako, David Dosoo, Love Ankrah, George Adjei, Seeba Amenga-Etego, and Seth Owusu-Agyei, Malaria Parasite Density Estimated with White Blood Cells Count Reference Value Agrees with Density Estimated with Absolute in Children Less Than 5 Years in Central Ghana, Malaria Research and treatment, Volume 2015, http://dx.doi.org/10.1155/2015/92367

34.Adu-Gyasi D, Asante KP, Newton S, Dosoo D, Amoako S, Adjei G, Amoako N, Ankrah L, Tchum SK, Mahama E, Agyemang V, Kayan K, Owusu-Agyei S, Evaluation of the Diagnostic Accuracy of CareStart G6PD Deficiency Rapid Diagnostic Test (RDT) in a Malaria Endemic Area in Ghana, Africa, Plos One I:10.1371/journal.pone.0125796 April 17, 201=

35. Adjei KK, Laar AK, Narh CT, Abdulai MA, Newton S, Owusu-Agyei S, Sam Adjei S. A comparative study on the availability of modern contraceptives in public and private health facilities in a peri-urban community in Ghana, Reproductive Health, 2015 DOI 10.1186/s12978-015-0058-

36. Ginsburg AM, Delarosa J, Brunette W, Levari S, Sundt M, Larson C, Agyemang CT, Newton S, Borriello G, Anderson R. mPneumonia: Development of an Innovative mHealth Application for Diagnosing and Treating Childhood Pneumonia and Other Childhood Illnesses in Low-Resource Settings. PLOS ONE OI: 2015 10.1371/journal.pone.0139625 October 16

37. Newton S, Owusu-Agyei S, Asante KP, Amoaful E, Mahama E, Tchum SK, Ali M, Adjei K, Davis CR, and Tanumihardjo SA  Vitamin A status and body pool size of infants before and after consuming fortified home-based complementary foods, Archives of Public Health (2016) 74:10 DOI 10.1186/s13690-016-0121-

38.NEOVITA Study Group* Timing of initiation, patterns of breastfeeding, and infant survival: prospective analysis of pooled data from three randomised trials, Lancet Glob Health. 2016 Apr;4(4):e266-75. doi: 10.1016/S2214-109(16)00040-

39. O'Leary M, Thomas S, Hurt L, Floyd S, Shannon C, Newton S, Thomas G, Amenga-Etego S, Tawiah-Agyemang C, Gram L, Hurt C, Bahl R, Owusu-Agyei S, Kirkwood B, Edmond K., Vaccination timing of low-birth-weight infants in rural Ghana: a population-based, prospective cohort study. Bull World Health Organ. 2016 Jun 1;94(6):442-451D. doi: 10.2471/BLT.15.159699

40. Gyan T, Strobel N, McAuley K, Shannon C, Newton S, Agyemang CT, Amenga-Etego S, Owusu-Agyei S,, Forbes D and Edmond K* Health service provider education and/or training in infant male circumcision to improve short- and long-term morbidity outcomes: protocol for systematic review Systematic Reviews (2016) 5:41 DOI 10.1186/s13643-016-0216-

42. Gyan T, McAuley K, Strobel NA, Shannon C, Newton S, Tawiah-Agyemang C, Amenga-Etego S, Owusu-Agyei S, Kirkwood B, Edmond KM. Determinants of morbidity associated with infant male circumcision: community-level population-based study in rural Ghana. Trop Med Int Health. 2016 Dec 19. doi: 10.1111/tmi.12829

43. O'Leary M, Edmond K, Floyd S, Hurt L, Shannon C, Thomas G, Newton S, Kirkwood B, Thomas S. Neonatal vaccination of low birthweight infants in Ghana.

Arch Dis Child. 2017 Feb;102(2):145-151. doi: 10.113

44. Kristy Hackett1,2* , Lindsey Lenters3, Ashley Vandermorris4, Curtis LaFleur5, Sam Newton6, Sidney Ndeki7 and Stanley Zlotkin4. How can engagement of adolescents in antenatal care be enhanced? Learning from the perspectives of young mothers in Ghana and Tanzania. BMC Pregnancy and Childbirth (2019) 19:184 https://doi.org/10.1186/s12884-019-2326-

45. Joyce Agyemang1, Sam Newton1, Isaac Nkrumah2, Joyce Mahlako Tsoka-Gwegweni3,4, Samuel Nambile Cumber3,5,6,&. Contraceptive use and associated factors among sexually active female adolescents in Atwima Kwanwoma District, Ashanti region-Ghana. Article  in  Pan African Medical Journal · January 2019 DOI: 10.11604/pamj.2019.32.182.1534

46. Nakua EK1, Owusu-Dabo E1, Newton S1, Adofo K2, Otupiri E1, Donkor P2, Mock C3. Occupational injury burden among gold miners in Ghana. Int J Inj Contr Saf Promot. 2019 Jun 5:1-7. doi: 10.1080/17457300.2018.151523

47. Emmanuel Kweku Nakua1* , Ellis Owusu-Dabo1, Samuel Newton1, Adofo Koranteng2, Easmon Otupiri3, Peter Donkor2 and Charles Mock4. Injury rate and risk factors among smallscale gold miners in Ghana. BMC Public Health (2019) 19:1368 https://doi.org/10.1186/s12889-019-7560-0

48. Thomas Gyan,1,2 Natalie A Strobel ,1 Kimberley McAuley,1 Caitlin Shannon,3 Sam Newton,4 Charlotte Tawiah-Agyemang,2 Seeba Amenga-Etego,2 Seth Owusu-Agyei,2,5 David Forbes1 and Karen Edmond. Health service provider education and/or training in infant male circumcision to improve short- and long-term morbidity outcomes: A systematic review. Journal of Paediatrics and Child Health (2019

49. Neonatal Vitamin A Supplementation Evidence group, Early neonatal vitamin A supplementation and infant mortality: an individual participant data metaanalysis of randomised controlled trial, (http:// dx. doi. org/ 10. 1136/ archdischild- 2018- 315242

50. WHO Immediate KMC Study Group impact of continuous Kangaroo Mother Care initiated immediately after birth (iKMC) on survival of newborns with birth weight between 1.0 to < 1.8kg: study protocol for a randomized controlled trial, WHO Immediate KMC Study Group Trials (2020) 21:280 https://doi.org/10.1186/s13063-020-4101-

51. Akuze J, Blencowe H, Waiswa P, Baschieri A, Gordeev VS, Kwesiga D, Fisker AB, Thysen SM, Rodrigues A, Biks GA, Abebe SM, Gelaye KA, Mengistu MY, Geremew BM, Delele TG, Tesega AK, Yitayew TA, Kasasa S, Galiwango E, Natukwatsa D, Kajungu D, Enuameh YA, Nettey OE, Dzabeng F, Amenga-Etego S, Newton SK, Tawiah C, Asante KP, Owusu-Agyei S, Alam N, Haider MM, Imam A, Mahmud K, Cousens S, Lawn JE; Every Newborn-INDEPTH Study Collaborative Group, Randomised comparison of two household survey modules for measuring stillbirths and neonatal deaths in five countries: the Every Newborn-INDEPTH study. Lancet Glob Health. 2020 Apr;8(4):e555-e566. doi: 10.1016/S2214-109X(20)30044-9

53. Pepito VCF, Newton S (2020) Determinants of HIV testing among Filipino women:Results from the 2013 Philippine National Demographic and Health Survey. PLoS ONE 15(5): e0232620.https://doi.org/10.1371/journal. pone.023262

54. Sherley and Newton. The association between area of residence and sufficient antenatal tetanus vaccination in women ages 15–49 in Afghanistan: an analysis of the 2015 DHS dataset. Global Health Research and Policy (2020) 5:51 https://doi.org/10.1186/s41256-020-00180-1

55, Yeetey Akpe Kwesi Enuameh*, Francis Dzabeng , Hannah Blencowe , Sanne M. Thysen, Solomon Mekonnen Abebe, Kwaku Poku Asante , Charlotte Tawiah , Vladimir Sergeevich Gordeev, Wisdom Adeapena , Doris Kwesiga, Simon Kasasa, Charles Zandoh , Md. Ali Imam, Seeba Amenga-Etego , Sam K. Newton1, Seth Owusu-Agyei, Joy E. Lawn , Peter Waiswa, Jenny A. Cresswell and the Every Newborn-INDEPTH Study Collaborative Group. Termination of pregnancy data completeness and feasibility in population based surveys: EN-INDEPTH study. Enuameh et al. Population Health Metrics 2020, 19(Suppl 1):12 https://doi.org/10.1186/s12963-020-00238-9

56, Aviva I Rappaport, Crystal D Karakochuk, Sonja Y Hess, Ralph D Whitehead, Jr.,Sorrel M L Namaste, Omar Dary, Megan E Parker, Lynnette M Neufeld, Leila M Larson, Sam Newton, Rita Wegmuller, Denish Moorthy. Variability in haemoglobin concentration by measurement tool and blood source: an analysis from seven countries, http://dx.doi.org/10.1136/ jclinpath-2020-206717).

57, Nicole Minckas, Melissa M. Medvedev, Ebunoluwa Adejuyigbe; Helen Brotherton; Harish Chellani; Abiy Seifu Estifanos,; Chinyere Ezeaka; Abebe G. Gobezayehu, Grace Irimu; Kondwani Kawaza,; Vishwajeet Kumar; Augustine Massawe; Sarmila Mazumder; Ivan Mambule; Araya Abrha Medhanyie; Elizabeth M. Molyneux; Sam Newton; Nahya Salim; Henok Tadele; Cally J. Tann; Sachiyo Yoshida,; Rajiv Bahl; Suman Rao PN Joy E. Lawn; on behalf of the COVID-19 Small and Sick Newborn Care Collaborative Group. Preterm care during the COVID-19 pandemic: a comparative risk analysis of neonatal deaths averted by kangaroo mother care versus mortality due to SARS-CoV-2 infection., EClinicalMedicine (2021), https://doi.org/10.1016/j. eclinm.2021.100733

58.Yaa Nyarko Agyeman¹ Sam Kofi Newton² Raymond Boadu Annor³ and Ellis Owusu-Dabo². The Effectiveness of the Revised Intermittent Preventive Treatment with Sulphadoxine Pyrimethamine (IPTp-SP) in the Prevention of Malaria among Pregnant Women in Northern Ghana. Journal of Tropical Medicine Volume 2020, Article ID 2325304, 9 pages https://doi.org/10.1155/2020/232530

59Yaa Nyarko Agyeman¹, Sam Newton², Raymond Boadu Annor³, Ellis Owusu-Dabo². Intermittent preventive treatment comparing two versus three doses of sulphadoxine pyrimethamine (IPTp-SP) in the prevention of anaemia in pregnancy in Ghana: A cross[1]sectional study. . PLoS ONE 16(4): e0250350. https://doi.org/10.1371/journal.pone.0250350

60.WHO Immediate KMC Study Group, Immediate “Kangaroo Care” and Survival of Infants with Low Birth Weight. NEJM oa2026486_Thu Apr 22 2021 11:46:19 (IN PRESS)