Prof. Alex Kwame Owusu-Ofori

Associate Professor

Dept: Clinical Microbiology
Dept of Clinical Microbiology,
School of Medicine and Dentistry,
College of Health Sciences
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Research Areas/Interests

Antimicrobial Resistance Transfusion -Transmitted Infections, including malaria, syphylis and other baceteria Methicillin-Resistant Staphylococcus Aur...~more

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Publications

    1. Narwortey DK, Owusu-Ofori A, Slotved HC, Donkor ES, Ansah PO, Welaga P, et al. Nasopharyngeal carriage of Streptococcus pneumoniae among healthy children in Kassena-Nankana districts of Northern Ghana. BMC Infect Dis. 2021;21(1):661.
    2. Janice J, Agyepong N, Owusu-Ofori A, Govinden U, Essack SY, Samuelsen O, et al. Carbapenem Resistance Determinants Acquired through Novel Chromosomal Integrations in Extensively Drug-Resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2021;65(7):e0028921.
    3. Gambrah E, Owusu-Ofori A, Biney E, Oppong C, Coffin SE. Diagnosis and treatment of urinary tract infections in hospitalized adults in Ghana: The role of the clinical microbiology laboratory in improving antimicrobial stewardship. Int J Infect Dis. 2021;102:497-500.
    4. Amponsah OKO, Buabeng KO, Owusu-Ofori A, Ayisi-Boateng NK, Hameen-Anttila K, Enlund H. Point prevalence survey of antibiotic consumption across three hospitals in Ghana. JAC Antimicrob Resist. 2021;3(1):dlab008.
    5. Ahmad Y, Heroes AS, Hume HA, Farouk M, Owusu-Ofori A, Gehrie EA, et al. Bacterial contamination of blood products in Africa. Transfusion. 2021;61(3):767-80.
    6. Okyere B, Owusu-Ofori A, Ansong D, Buxton R, Benson S, Osei-Akoto A, et al. Point prevalence of asymptomatic Plasmodium infection and the comparison of microscopy, rapid diagnostic test and nested PCR for the diagnosis of asymptomatic malaria among children under 5 years in Ghana. PLoS One. 2020;15(7):e0232874.
    7. Gambrah E, Owusu-Ofori A, Biney E, Oppong C, Coffin SE. Diagnosis and treatment of urinary tract infections in hospitalized adults in Ghana: The role of the clinical microbiology laboratory in improving antimicrobial stewardship. Int J Infect Dis. 2020;102:497-500.
    8. Stewardson AJ, Marimuthu K, Sengupta S, Allignol A, El-Bouseary M, Carvalho MJ, et al. Effect of carbapenem resistance on outcomes of bloodstream infection caused by Enterobacteriaceae in low-income and middle-income countries (PANORAMA): a multinational prospective cohort study. Lancet Infect Dis. 2019;19(6):601-10.
    9. Konadu DG, Owusu-Ofori A, Yidana Z, Boadu F, Iddrisu LF, Adu-Gyasi D, et al. Prevalence of vulvovaginal candidiasis, bacterial vaginosis and trichomoniasis in pregnant women attending antenatal clinic in the middle belt of Ghana. BMC Pregnancy Childbirth. 2019;19(1):341.
    10. Donkor GY, Dontoh E, Owusu-Ofori A. A cross-sectional study on the prevalence of antibiotic use prior to laboratory tests at two Ghanaian hospitals. PLoS One. 2019;14(1):e0210716.
    11. Agyepong N, Govinden U, Owusu-Ofori A, Amoako DG, Allam M, Janice J, et al. Genomic characterization of multidrug-resistant ESBL-producing Klebsiella pneumoniae isolated from a Ghanaian teaching hospital. Int J Infect Dis. 2019;85:117-23.
    12. Agyepong N, Govinden U, Owusu-Ofori A, Allam M, Ismail A, Pedersen T, et al. Whole-Genome Sequences of Two Multidrug-Resistant Acinetobacter baumannii Strains Isolated from Patients with Urinary Tract Infection in Ghana. Microbiol Resour Announc. 2019;8(31).
    13. Acheampong G, Owusu M, Owusu-Ofori A, Osei I, Sarpong N, Sylverken A, et al. Chromosomal and plasmid-mediated fluoroquinolone resistance in human Salmonella enterica infection in Ghana. BMC Infect Dis. 2019;19(1):898.
    14. Agyepong N, Govinden U, Owusu-Ofori A, Essack SY. Multidrug-resistant gram-negative bacterial infections in a teaching hospital in Ghana. Antimicrob Resist Infect Control. 2018;7:37.
    15. Adusei KA, Owusu-Ofori A. Prevalence of Plasmodium parasitaemia in blood donors and a survey of the knowledge, attitude and practices of transfusion malaria among health workers in a hospital in Kumasi, Ghana. PLoS One. 2018;13(11):e0206303.
    16. Sarkodie F, Hassall O, Owusu-Dabo E, Owusu-Ofori S, Bates I, Bygbjerg IC, et al. Improving the screening of blood donors with syphilis rapid diagnostic test (RDT) and rapid plasma reagin (RPR) in low- and middle-income countries (LMIC). Transfus Med. 2017;27(1):52-9.
    17. Owusu-Ofori AK, Owusu-Ofori SP, Bates I. Detection of adverse events of transfusion in a teaching hospital in Ghana. Transfus Med. 2017;27(3):175-80.
    18. Sarkodie F, Ullum H, Owusu-Dabo E, Owusu-Ofori S, Owusu-Ofori A, Hassall O. A novel strategy for screening blood donors for syphilis at Komfo Anokye Teaching Hospital, Ghana. Transfus Med. 2016;26(1):63-6.
    19. Owusu-Ofori A, Gadzo D, Bates I. Transfusion-transmitted malaria: donor prevalence of parasitaemia and a survey of healthcare workers knowledge and practices in a district hospital in Ghana. Malar J. 2016;15:234.
    20. Allain JP, Owusu-Ofori AK, Assennato SM, Marschner S, Goodrich RP, Owusu-Ofori S. Effect of Plasmodium inactivation in whole blood on the incidence of blood transfusion-transmitted malaria in endemic regions: the African Investigation of the Mirasol System (AIMS) randomised controlled trial. Lancet. 2016;387(10029):1753-61.
    21. Allain JP, Assennato SM, Osei EN, Owusu-Ofori AK, Marschner S, Goodrich RP, et al. Characterization of posttransfusion Plasmodium falciparum infection in semi-immune nonparasitemic patients. Transfusion. 2016;56(9):2374-83.
    22. Owusu-Ofori S, Kusi J, Owusu-Ofori A, Freimanis G, Olver C, Martinez CR, et al. Treatment of Whole Blood With Riboflavin and UV Light: Impact on Malaria Parasite Viability and Whole Blood Storage. Shock. 2015;44 Suppl 1:33-8.
    23. Owusu-Ofori AK, Betson M, Parry CM, Stothard JR, Bates I. Transfusion-transmitted malaria in Ghana. Clin Infect Dis. 2013;56(12):1735-41.
    24. Owusu-Ofori AK, Bates I. Impact of inconsistent policies for transfusion-transmitted malaria on clinical practice in Ghana. PLoS One. 2012;7(3):e34201.
    25. Owusu-Ofori AK, Parry CM, Bates I. Transfusion-transmitted syphilis in teaching hospital, Ghana. Emerg Infect Dis. 2011;17(11):2080-2.
    26. Owusu-Ofori AK, Parry C, Bates I. Transfusion-transmitted malaria in countries where malaria is endemic: a review of the literature from sub-Saharan Africa. Clin Infect Dis. 2010;51(10):1192-8.
    27. Owusu-Ofori A, Jennings R, Burgess J, Prasad PA, Acheampong F, Coffin SE. Assessing hand hygiene resources and practices at a large african teaching hospital. Infect Control Hosp Epidemiol. 2010;31(8):802-8.
    28. Macete EV, Sacarlal J, Aponte JJ, Leach A, Navia MM, Milman J, et al. Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial. Trials. 2007;8:11.
    29. Polage CR, Bedu-Addo G, Owusu-Ofori A, Frimpong E, Lloyd W, Zurcher E, et al. Laboratory use in Ghana: physician perception and practice. Am J Trop Med Hyg. 2006;75(3):526-31.
    30. Owusu-Ofori A, Agbenyega T, Ansong D, Scheld WM. Routine lumbar puncture in children with febrile seizures in Ghana: should it continue? Int J Infect Dis. 2004;8(6):353-61.
    31. Planche T, Agbenyega T, Bedu-Addo G, Ansong D, Owusu-Ofori A, Micah F, et al. A prospective comparison of malaria with other severe diseases in African children: prognosis and optimization of management. Clin Infect Dis. 2003;37(7):890-7.
    32. Owusu-Ofori A, Scheld WM. Treatment of Salmonella meningitis: two case reports and a review of the literature. Int J Infect Dis. 2003;7(1):53-60.
    33. Agbenyega T, Planche T, Bedu-Addo G, Ansong D, Owusu-Ofori A, Bhattaram VA, et al. Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children. J Clin Pharmacol. 2003;43(4):386-96.
    34. Krishna S, Planche T, Agbenyega T, Woodrow C, Agranoff D, Bedu-Addo G, et al. Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria. Antimicrob Agents Chemother. 2001;45(2):509-16.
    35. Krishna S, Nagaraja NV, Planche T, Agbenyega T, Bedo-Addo G, Ansong D, et al. Population pharmacokinetics of intramuscular quinine in children with severe malaria. Antimicrob Agents Chemother. 2001;45(6):1803-9.
    36. Cowan G, Planche T, Agbenyega T, Bedu-Addo G, Owusu-Ofori A, Adebe-Appiah J, et al. Plasma glutamine levels and falciparum malaria. Trans R Soc Trop Med Hyg. 1999;93(6):616-8.

     

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