Grants/Funds Awarded
- Role: Principal Investigator-Ghana Team: Severe Malaria A Research Trials (SMAART) consortium: Prospective observational study to describe the changing epidemiology and clinical outcomes of severe malaria in African children. Sponsored by WELLCOME TRUST, UK: 03/2020- 2/2023:
- Role: Principal Investigator: Safety Arm of the World Health Organization (WHO) RTS,S Malaria Vaccine Pilot Evaluation (MVPE)-Malaria Vaccine Implementation Programme in Ghana. Sponsored by ethe WHO 04/2017 to date
- Role: Co-Investigator: Austere Consortium for Enhanced Sepsis Outcome ACESO (study): The aim of ACESO is to improve survival for patients with sepsis through development of host-based diagnostic/prognostic assays and evidence-based clinical management. The Ghana site since 2015 has recruited over 300 patients reporting to the Komfo Anokye Teaching Hospital with evidence of sepsis for genetic and other advanced molecular assessments. sponsored Henry M. Jackson Foundation-USA 12/2015-present:
- Role: Co-Principal Investigator: Phase IIb randomized, open-label, controlled, multi-center study of the efficacy, safety and immunogenicity of GSK Biologicals’ candidate malaria vaccine RTS,S/AS01E evaluating schedules with or without fractional doses, early Dose 4 and yearly doses, in children 5-17 months of age living in sub-Saharan Africa (Malaria 094). 09/2017 to 11/2021. Sponsor by GSK
- Role: Co-Principal Investigator: Phase IIIb Randomized, Open, Controlled, Multi-Center Study to Evaluate the Immunogenicity and Safety of the RTS,S/AS01E Candidate Malaria Vaccine, when Administered as Primary Vaccination at 6,7.5 and 9 Months of Age with or without Co-Administration of Measles, Rubella and Yellow Fever Vaccines followed by RTS,S/AS01E Booster Vaccination 18 Months Post Dose to Children Living in Sub-Saharan Africa (Malaria 073). Sponsored by GSK. 05/2017 to 09/2020.
- Role: Principal Investigator: Surveillance of Pediatric Bacterial Meningitis and Sepsis in Ghana. Surveillance of children presenting with bacterial meningitis and sepsis in the Komfo Anokye Teaching Hospital. Sponsored by WHO/AFRO. 01/2003 to date