Prof. Ellis Owusu-Dabo

Professor


Dept: Global and International Health
Office of the Vice-Chancellor
Central Administration
Kwame Nkrumah University of Science and Technology
Kumasi-Ghana

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Research Areas/Interests

The role of candidate microRNAs in the T cell response during acute and latent tuberculosis; to determine the exact immunological role played by micro...~more

My full CV

Grants/Funds Awarded

2019-2022    Severe Typhoid in Africa (SETA) Plus Program – Ghana. Bill and Melinda Gates Foundation (PI; $1,000,000). Total amount helped to mobilize $3 million USD

2019-2020    Multi Stakeholder Planning Workshop for the Development of Master of Public Health in non-communicable diseases at the KNUST School of Public Health (PI). National Institutes of Health (NIH) Grant Number 1D71TW011490-01, ($45,670); with additional commitment for $240,000 per annum for five years.

 

2019-2023    Advancing a GMMA-based vaccine against invasive non-typhoidal salmonellosis through Phase I trial in Europe and sub-Saharan Africa (Co-PI; 194,226.17). H2020-SC1-BHC-15-2018 two-stage-RTD. Grant number 815439. Total amount helped to mobilize € 6.8 million

2019-2023    European Developing Countries Clinical Trial Partnerships (2) EDCTP2 Effect of a novel typhoid conjugate vaccine in Africa: a multicenter study in Ghana and the Democratic Republic of the Congo — THECA (PI; 5,179,550.71). Total amount helped to mobilize € 13, million

2018–2020   European Union, Type 2 diabetes and obesity among sub-Saharan African native and migrant populations: dissection of environment and endogenous predisposition. Objective: To determine the socioeconomic as well as genetic factors predisposing to T2DM (PI; 153,000). Total amount helped to mobilize € 300, 000.

2018-2021    National Institutes of Health (NIH) Sickle Cell Disease Genomics Network of Africa project (SICKLEGEN AFRICA)-Co-PI; USD $500, 000 (Grant Number 1U54HL141011-01). Total amount helped to mobilize USD $5 million.

2018-2021    The Dynamics of Healthcare Utilization in the Context of RTS,S/AS01 Vaccine Introduction in Ghana, Kenya, and Malawi. A qualitative longitudinal study. (Co-PI; $211,543.10). Total amount helped to mobilize $ USD 2 million.

2018-2019    Tick-borne and Mosquito Infections Surveillance; U.S. Naval Medical Research Unit No. 3 (NAMRU-3), Ow (PI; $45,000)

 

2017-2020    International Development Research Centre (IDRC), Reducing child mortality: The Role of Mobile Electronic Health Information System (108678-001) (PI; 743, 000 CAD).

 

2017-2020    Medical Research Council, United Kingdom Improve research capacity in LMICs to conduct high quality studies that will generate evidence on how to reduce morbidity and mortality caused by tobacco use and to advance key development priorities (Co-PI; £247,954).. Total amount helped to mobilize £3 million.

2017             WHO / TDR CRDF reintegrationl Capacity (WHO-R) (Co-PI; €15,104.41)

2017             Universitaetsklinikum Hamburg-Eppendort (UKE) (Co-PI; €2,260) Meningitis carrier study in Brong Ahafo (M 17)

2017             Global Fund Prevalence study of asymptomatic malaria and anaemia among schools’ pupils in four (4) operational districts of Anglogold Ashanti (Ghana) Malaria Limited (AGA 1) (PI; GHC 455,055)

2017             University of Pennsylvania Designing point of care diagnostics for the diagnosis of tuberculosis in children (APOC III) (PI; $63,192.50)

2016-2017    BMBF (DZIF) Antimicrobial Resistance in Ghana - prevalence and nosocomial transmission of ESBL-, carbapenemase-producing and ciprofloxacin-resistance (R 16) (Co-PI; €5,850)

2016             German Research Council (DFG) To examine differences of parasite growth in erythrocytes from donors with different genotypes on specific ATP2B40SNPs and measure the expression oft he gene in dependence o f these Genotypes (ATP2) (Co-PI; €11,904)

2016             University of Pennsylvania Designing point of care diagnostics for the diagnosis of tuberculosis in children (APOC II) (PI; $35,864)

2015-2016    Global Fund, Tuberculosis Drug Resistance Survey for Ghana, Objective: To determine drug resistance profile of patients with pulmonary tuberculosis in Ghana. (PI; $200,000)  

2015-2019    Severe Typhoid in Africa (SETA): The goal of this study is to estimate the burden and severity of invasive salmonellosis; report the long-term sequelae and associated cost of illness; and assess the immune response to natural infectionBill and Melinda Gates Foundation, (Co-PI; $1,200,000).

 

2015-2017    German Research Foundation, Assessing the effect of neglected tropical diseases on plasmodium falciparum transmission in area of co-endemicity. (PI; 218,610)

 

2015-2018    University of Pittsburgh, Organ damage in sickle cell disease patients at Komfo Anokye Teaching Hospital. (PI; $250,000). Total amount helped to mobilize $ 1 million.

2015-2017    German Research Foundation (DFG), Mansonella Perstans co-infection with mycobacterium infection. Objective: To determine immunological factors that determines severity of mycobacterial co-infection with mansonella perstans co-infection. (Co-PI; 384,600)

2015-2019    University of Pittsburgh. The concept is to better understand the process of sickle cell organ damage and be able to suggest biomarkers for vaccine and drug deveopment in particular in relation to pain management (ORDISS) (Co-PI; $250,000)

2015-2016    DZIF This project is an extension of previous work on profiling extensive genetic predispositions of patients to pulmonary TB within the TB DRS (DZIF TB). (PI; €44,336)

2015-2018    German Research Council (DFG). Assessing the effect of schistosomiasis infestation on plasmodium falciparum transmission in co-endemic areas of Lameberene, Gabon and Kumasi, Ghaan.  This project hast he main aim of determining immunological response in both schistosomiasis infected and non-schistosomiasis infected patients in a prospective study (TransMal) (PI; €218,610)

2015-2018    Bill and Melinda Gates Foundation / Internation Vaccine Institute. The aim of this study is to generate typhoid Fever and invasive Non-Ty[hoidal Salmonella (iNTS) disease burden and immunological data to drive vaccine development and inform evidence-based prevention and control policy (including vaccine policy) in sub Saharran Africa (SETA) (Co-PI; $695,774)

2015             Volkswagen Stiftung (VW Foundation). Construction of the cold house facility for KCCR, KNUST, Kumasi. (Lead; €221,600)

2014-2019    German Centre for Reseach (DFG); (Co-PI): The main objective of this multinational and multicenter study is to determine the influence of M. perstans infection and their Wolbachia endosymbionts on host immunity against mycobacterial infection, BCG vaccination efficacy, and disease susceptibility in children and adolescents. (261,110)

2014             BNI via European Union Bovine (APARET Mini III) (Co-PI; $5,000)

2013-2018    BMBF (DZIF) The most relevant ids and pathogens causing sever childhood febrile illnesses shall be characterized using common laboratory standard methods.  As a first project, it is planned to create a network of platforms for the evaluation of innovative point-of-care (POC) diagnostics, in particular for the use in resource-poor countries where malaria is endemic. (Co-PI; €280,551)

2013-2015    DZIF The concept behind this study is to explore othe causes of fever among children with fever at the Agogo Hospital (FWS) (Co-PI; 316,291)

2013-2014    Universitaetsklinikum Hamburg-Eppendort (UKE). Group B streptococcal colonization in pregnant women and related neonatal infections-an epidemiological study in the Ashanti Region of Ghana (GBS-01) (Co-PI; €6,500)

2013-2017    BNI Hamburg Owusu-Dabo Research Group on non-communicable diseases (PI; €350,000)

2013-2017    National Institutes of Health (NIH) H3ABIONET. To build research capacities in bioinformatics through a consortium network of institutions to provide backbone to NIH funded projects on genoics of African diseases (Co-PI; $255,855.96). Total amount helped to mobilize $12 million.

 

2013-2014    Global Fund Malaria among selected districts.  An assessment of Point prevalence & Vector Profile (ANGLO II) (PI; $39,204)

2013-2014    BMBF Mobile phone based electronic Health Information and Surveillance System for Africa: Concept and pilot study (eHISS) (Co-PI; €68,935). Total amount helped to mobilize € 500,000.

2013             BNI via European Union Sero-Molecular & Risk factors of Brucella Infection among slaughterhouse workers and butchers in Kumasi, Ghana. (APARET Mini II). (Co-PI; $5,000)

2012-2018    Appropriate Point of Care diagnostics, University of Pennsylvania School of Engineering (PI; $320,000).

2012-2014    European Union, The overall aim of the RODAM project is to contribute to the understanding of the complex interplay between environment, behaviour and genetic features in T2D and obesity among one homogeneous SSA immigrants to Europe and their compatriots in SSA, and to identify specific risk factors to guide intervention and prevention and to provide a basis for improving diagnosis and treatment. (PI; 280,480)

2012-2013    BNI via European Union, Molecular epidemiology of Methicillin Resistant Staphulococcus aureus among health individuals and patients with dermatological infections. (APARET Mini I). (Co-PI; $5,000)

2011-2015    DAHW, Germany, The role of candidate microRNAs in the T cell response during acute Tuberculosis and latent M tuberculosis infection. Objective: To determine the exact immunological role played by microRNAs in TB infection (PI: 250,000).

2011-2014    BNI via European Union, To build sustainable research capacities in Africa. By assigning several qualified fellows to conducting research grant writing activities and providing support to them through a network of peers, Mentors, and supervisors, we aim to stimulate research activities and to increase the number of future grants that can be attracted (APARET Main) (PI; €74,076.50).

2011             Anglogold Ashanti Malaria Control Program, Assessment of Malaria Parasite Rates in Sentinel Schools in Preparation of an Indoor Residual Spray Intervention (ANGLO I) (PI; 21,000)

2010-2014    ANDi Designation of KCCR as a Centre of Excellence in applied biomedical research (PI; €23,809.50)

2004-2007    Bill and Melinda Gates Foundation, Establishment of Programme in Reproductive Health, SMS, KNUST (Co-Investigator); One Million $USD

2003-2005    Teaching and Research Innovation Fund (TALIF) award, (USD $ 600, 000)

2002-2006    Genetic Susceptibility Factors for Tuberculosis (German Ministry of Education and Research-BMBF); Three Million Deutschmarks DM (Co-Principal Investigator/Coordinator)


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