Prof. Isaac Kingsley Amponsah

Associate Professor


Dept: Pharmacognosy
Department of Pharmacognosy, Faculty of Pharmacy and Pharm. Sciences, KNUST
Tackie Building RM C216

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Research Areas/Interests

Clinical trials of herbal products Standardisation of herbal products Quality control of finished herbal products and raw materials Socio-cultural as...~more

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Publications

    2021

    • Ramos, G. F., Amponsah, I. K., Harley, B. K., Jibira, Y., Baah, M. K., Adjei, S., Armah, F. A., Mensah, A. Y. (2021). Triterpenoids mediate the antimicrobial, antioxidant, and anti-inflammatory activities of the stem bark of Reissantia indica. J Appl Pharm Sci, 11(05):039–048.
    • Amponsah, I. K., Atchoglo, P. K., Ackah, R. Y., Tsouh Fokou, P. V., Aboagye, S. Y., Yeboah-Manu, D., Appiah-Opong, R., & Mensah, A. Y. (2021). In vitro Anti-Mycobacterium ulcerans and cytotoxic activities of some selected medicinal plants and an indoloquinoline alkaloid. International Journal of mycobacteriology, 10(1), 60–65. https://doi.org/10.4103/ijmy.ijmy_243_20.
    • Harley, B., Amponsah, I. K., Ben, I. O., Adongo, D. W., Mireku-Gyimah, N. A., Baah, M.K., and Fleischer, T. C. (2021). Myrianthus libericus: Possible mechanisms of hypoglycaemic action and in silico prediction of pharmacokinetics and toxicity profile of its bioactive metabolite, friedelan-3-one. Biomedicine & Pharmacotherapy, 137, 111379.
    • Baidoo, M. F., Mensah, A. Y., Ossei, P. P. S., Asante-Kwatia, E. and Amponsah, I. K. (2021). Wound healing, antimicrobial and antioxidant properties of the leaf and stem bark of Entada africana Guill. & Perr. South African Journal of Botany, 137:52-59.
    • Frempong, T. F., Badu, M., Boamah, V. E., Amponsah, I. K., Agbemade, B., Boateng, A. R. and Boadi, O. B. (2021). Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica. Chemistry Africa. https://doi.org/10.1007/s42250-021-00249-5.
    • Armah, F. A., Henneh, I. T., Amponsah, I. K., Biney, R. P., Malcolm, F., Alake, J., Ahlidja, W., Ahmed, M. A., Adokoh, C. K., Adukpo, G. E., Acheampong, D. O., Gathumbi, P. K. (2021). "Antidepressant and Anxiolytic Effects and Subchronic Toxicity of the Aerial Parts of Psychotria ankasensis J.B.Hall (Rubiaceae) in Murine Models", Evidence-Based Complementary and Alternative Medicine, vol. 2021, Article ID 5543320, 18 pages. https://doi.org/10.1155/2021/5543320
    • Anokwah, D., Asante-Kwatia, E., Mensah, A. Y., Danquah, C. A., Harly, B. K., Amponsah, I. K., Oberer, L. (2021). Bioactive constituents with antibacterial, resistance modulation, anti-biofilm formation and efflux pump inhibition properties from Aidia genipiflora stem bark. Clin Phytosci 7, 28 (2021). https://doi.org/10.1186/s40816-021-00266-4

    2020

    • Amponsah, K. I., Ampofo K. E., Oppong Bekoe, S., Harley, K. B., Armah, A. F., Adjei, S., and Baah, K.M. (2020). Standardisation of Holarrhena floribunda (G. Don) Durand & Schinz: pharmacognostic evaluation and HPLC profiling of some of its steroidal alkaloids as chemical markers. International Journal of Research in Pharmaceutical Sciences, 11(SPL4), 2710-2725. https://doi.org/10.26452/ijrps.v11iSPL4.4545
    • Amponsah, I. K., Armah, F., Alake, J., Harley, B., Ampofo, E. K., Asante-Kwatia, E., Clinton, A. B., Amoani, B. and Henneh, I. T. (2020). In-vitro Anti-cercarial activity of extracts and steroidal alkaloids from the stem bark of Holarrhena floribunda (G. Don) Dur. & Schinz. International Journal of Phytomedicine, 12(3):069-078.
    • Ofori, A. A., Amponsah, K. I., Mensah, M. L. K., Turkson, B. K., Baidoo, M., Orman, E., Bayor, M. T. (2021). Utilization of Plants for Medicinal Purposes and Concerns with Endangered Plant Species from Ghana. Trad Integr Med. 6(1):24-40.
    • Ampofo, E., Amponsah, I. K., Asante-Kwatia, E., Armah, F. A., Atchoglo, P. K. and Mensah, A. Y. (2020). Indigenous medicinal plants as biofilm inhibitors for the mitigation of antimicrobial resistance. Advances in Pharmacological and Pharmaceutical Sciences. vol. 2020, Article ID 8821905, 10 pages, 2020. https://doi.org/10.1155/2020/8821905
    • Harley, B. K., Dickson, R., Amponsah, I. K., Ben, I. O., Adongo, D. W., Fleischer, T. C. and Habtemariam, S. (2020). Flavanols and triterpenoids from Myrianthus arboreus ameliorate hyperglycaemia in streptozotocin-induced diabetic rats possibly via glucose uptake enhancement and α-amylase inhibition. Biomedicine and Pharmacotherapy, 132: 10847.
    • Harley, B. K., Dickson, R. A., Amponsah, I. K., Ngala, R. A., Berkoh, D. and Fleischer, C. (2020). Antidiabetic effect of Chrysophyllum albidum is mediated by enzyme inhibition and enhancement of glucose uptake via 3T3-L1 adipocytes and C2C12 myotubes. Asian Pacific Journal of Tropical Biomedicine, 10(9): 387-396.
    • Baah, M. K., Mensah, A. , Asante-Kwatia, E., Amponsah, I. K., Forkuo, A. D., Harley, B. K. and Adjei, S. (2020). In vivo antiplasmodial activity of different solvent extracts of Myrianthus libericus stem bark and its constituents in Plasmodium berghei-infected mice. Evidence-Based Complementary and Alternative Medicine. vol. 2020, Article ID 8703197, 10 pages, 2020. https://doi.org/10.1155/2020/8703197
    • Turkson, B. K., Mensah, M. K., Amponsah, I. K., Mensah, A. Y., Achaab, E., Mensah, R. B., Atakorah, E., Ofori Attah, E., Zoiku. (2020). In vitro and in vivo Activity of Mist Amen Fevermix and Edhec Malacure, Polyherbal Antimalarial Products on Field Isolates of Plasmodium falciparum and Plasmodium berghei. Discovery Phytomedicine, 7(3): 97-102
    • Evelyn Afua Mireku, Abraham Yeboah Mensah, Isaac Kingsley Amponsah, Cynthia Amaning Danquah, Daniel Anokwah, Michael Kwesi Baah. (2018). Antimicrobial pentacyclic triterpenes and glycosides from the stem bark of Cussonia bancoensis. Natural product research, 34(6): 859-862.
    • Turkson, B. , Mensah, M., Sam, G. H., Mensah, A. Y., Amponsah, I. K., Ekuadzi, E., Komlaga, G., and Achaab, E. (2020). Evaluation of the Microbial Load and Heavy Metal Content of Two Polyherbal Antimalarial Products on the Ghanaian Market. Evidence-based complementary and alternative medicine: eCAM, 2020, 1014273. https://doi.org/10.1155/2020/1014273
    • Tetteh, A. W., Thomford, K. P., Mensah, M. L., Boadu, K. O., Thomford, A. K., Amposah I. K., Amofa, G., Turkson, B. K., Agyemang, M. O., Owusu-Ansah, E. D. (2020). Ghanaian herbal medicines for malaria: An Evaluation of the Clinical Safety and Effectiveness of “Time Herbal Mixture” in uncomplicated malaria. Phcog Res, 2020;12:71-5
    • Yakubu, J., Boakye-Gyasi, E., Abotsi, W. K. M., Amponsah, I. K., Adongo, D. W. and Woode, E. (2020). Hydroethanolic Stem Bark Extract of Burkea africana Attenuates Vincristine- Induced Peripheral Neuropathy in Rats. Volume 2020, Article ID 7232579, 14 pages https://doi.org/10.1155/2020/7232579.

    2019

    • Baidoo, M. ,  Asante-Kwatia,  E.,  Mensah,  A. Y.,  Sam,  G. H.,  Amponsah,  I. K.  (2019). Pharmacognostic characterization and development of standardization parameters for the quality control of Entada africana Guill. & Perr. Journal of Applied Research on Medicinal and Aromatic Plants, 12:36-42

    2018

    • Appiah, B., Amponsah, I. K., Poudyal A. and Mensah, M. L. K. (2018). Identifying strengths and weaknesses of the integration of biomedical and herbal medicine units in Ghana using the WHO Health Systems Framework: a qualitative study. Accepted, BMC Complementary and Alternative Medicine, 18(1):286. doi: 10.1186/s12906-018-2334-
    • Mireku, E. A., Mensah, A. Y., Amponsah, I. K., Danquah, C. A., Anokwah, D. and Baah, M. K. (2018). Antimicrobial pentacyclic triterpenes and glycosides from the stem bark of Cussonia bancoensi. Natural Products Research, 5:1-4 doi.org/10.1080/14786419.2018.1503262
    • Mbatchou, V. C., Dickson, R. A., Amponsah, I. K., Mensah, A. Y. and Habtemariam, S. (2018). Protection effect of the anthraquinones, cassiatorin and aurantio-obtusin from seeds of Senna tora against cowpea weevil attac. Asian Pacific Journal of Tropical Biomedicine, 8(2): 98-105.
    • Armah, F. , Amponsah, I. K., Mensah, A. Y., Dickson, R. A., Steenkamp, P. A., Madala, N. E. and Adokoh. (2018). Leishmanicidal activity of the root bark of Erythrophleum ivorense (Fabaceae) and the identification of some of its compounds by ultr-performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-QTOF-MS/MS). Journal of Ethnopharmacology, 211:207-216.
    • Mireku-Gyimah, N. A., Sarpong, , Amponsah, I. K., Mensah, A. Y. and Dickson, R. A. (2018). Comparative Pharmacognostic Studies of two Ghanaian Medicinal Plants: Saba senegalensis and Saba thompsonii. International Journal of Pharmaceutical Sciences and Research, 9(4):100-12. doi: 10.13040/IJPSR.0975-8232.9(4):1000-12
    • Amoateng, P.,  Quansah,  E.,  Karikari,  K.,  Asase,  A.,  Osei-Safo,  D.,  Kukuia,  K. K. E., Amponsah, I. K. and Nyarko, A. K. (2018). Medicinal Plants Used in the Treatment of Mental and Neurological Disorders in Ghana, Evidence-Based Complementary and Alternative Medicine, vol. 2018, Article ID 8590381, 14 pages,  https://doi.org/10.1155/2018/8590381
    • Armah, F., Amoani, B., Henneh, I. T., Dickson, R. A., Adokoh, C., Amponsah, I. K., Adu- Gyamfi, C. and Acheampong, D. O. (2018). In vitro Cercaricidal Activity of Fractions and Isolated Compounds of Erythrophleum ivorense (Fabaceae) Root Bark against Schistosoma haematobium. International Journal of Tropical Disease & Health, 34(3): 1-9.

    2017

    • Mbatchou, V., Tchouassi, D. P., Dickson, R. A., Annan, K., Mensah, A. Y., Amponsah, I. K., Jacobs, J. W., Cheseto., X., Habtemariam, S. and Torto, B. (2017). Mosquito larvicidal activity of Cassia tora seed extract and its key anthraquinones aurantio-obtusin and obtusin. Parasites and Vectors, DOI 10.1186/s13071-017-2512
    • Tetteh, A. W., Mensah, M., Boadu, K. O., Thomford, K. P., Agyemang, M. O., Annan, K., Dickson, R., Mensah, A. Y., Amposah, I. K., Ekuadzi, E. and Owusu-Ansah, E. D. (2017). Clinical Evaluation of the Safety and Effectiveness of Adutwumwaa Malamix: A Polyherbal Product for the Treatment of Uncomplicated Malaria in Ghana. Journal of Applied Pharmaceutical Science, 7(07):040-045.
    • Ramos, E. K., Ampofo, E., Mensah, A. Y., Sarpong, F. M. and Amponsah, I. K. (2017). Anti- inflammatory and anti-oxidant activity of Dialium dinklagei Harms. (Leguminosae). World Journal of Pharmaceutical Sciences, 5(4): 6-12.
    • Kumathia, E. K., Annan, K., Dickson, R., Mensah, A. Y., Amponsah, I. K., Appiah, A. A., Tung, N. H., Tung, N. H., Edoh, D. A. and Habtemariam S. (2017). Antiinflammatory and analgesic effects in rodent models of ethanol extracts of Clausena anisata roots and their chemical constituents. Natural Products Communications, 12(1): 67-72.

    2016

    • Amponsah, I. K., Mensah, A., Ampofo, E. K., Bekoe, S. O., Sarpong, F. M. and Jibira, Y. (2016). Pharmacognostic studies of the leaves and seeds of Cassia occidentalis (Linn.) (Leguminosae). Journal of Pharmacognosy and Phytochemistry, 5(3): 250-255.
    • Anokwah, D., Mensah, A. Y., Amponsah, I. K., Mireku, E. A. and Mintah, D. N. (2016). Anti-inflammatory, anti-oxidant and antimicrobial activities of the stem bark of Psydrax subcordata. Pharmacia Lettre, 8(20):21-
    • Sarpong, F. M., Armah, A., Amponsah, I. K. and Atchoglo, P. K. (2016). Antinociceptive Ecdysteroids and other constituents of Palisota hirsuta K. Schum (Commelinaceae). Journal of Applied Pharmaceutical Science, 6 (10): 147-153.
    • Sarpong, M., Amponsah, I. K., Armah, F. A., Jibira, Y. and Gyamfi, R. (2016). Anti-inflammatory and antioxidant activity of the ethanolic stem bark extract of Pachypodanthium staudtii Engl. & Diels (Family Annonaceae). World Journal of Pharmaceutical Sciences, 4(7):73—77.
    • Amponsah, I. K., Orman, E., Mensah, A. Y., Sarpong, F. M., Armah, F. A. and Sarpong, L. M. (2016). Development and validation of a radical scavenging antioxidant assay using potassium permanganate. Journal of Scientific and Innovative Research, 5(2): 36-42.
    • Kumatia, E., Annan, K., Dickson, R. A., Mensah, A. Y., Amponsah, I. K., Tung, N. H., Ocloo, A. and Habertamariam, S. (2016). Anti-inflammatory and analgesic activities of Annickia polycarpa stem back and its constituents. Der Pharmacia Lettre, 8 (13):42-52.
    • Sarpong, M., Sarpong, F. M. and Amponsah, I. K. (2016). Antiplasmodial activity of the leaves and stem bark of Carapa procera and Alstonia boonei. Der Pharmacia Lettre, 8 (3):116-122.

    2015

    • Armah, F. A., Annan, K., Mensah, A. Y., Amponsah, I. K., Tocher, D. A. and Habtemariam, S. (2015). Erythroivorensin: a novel anti-inflammatory diterpene from the root-bark of Erythrophleum ivorense (A Chev.). Fitoterapia, 105:37-42.

    2014

    • Amponsah, I. K.,  Mensah,  A.,  Otoo,  A.,  Mensah,  M. L. K.  and  Jato,  J.  (2014). Pharmacognostic standardisation of Hilleria latifiolia (Lam.) H. Walt (Phytolaccaceae). Asian Pacific Journal of Tropical Biomedicine, 4(22): 941- 946.
    • Amponsah, I. K., Annan, K., Koffour, G. A., Sarkodie, J. A., Umerie, I. J. and Osei-wusu, S. (2014). Anti-inflammatory and antioxidant properties of the ethanolic stem bark extract of Artocarpus altilis (Parkinson) Fosberg (Moraceae). Der Pharmacia Lettre, 6(3):211-217.
    • Awarikabey, E., Amponsah, I. K. and Woode, M. Y. (2014). The value of the cocoa bean shell (hull) and the effect of various processing methods on the phyto-constituents and antioxidant activity of the nib and shell. Journal of Natural Product and Plant Resources, 4 (3):58-64.
    • Dickson, R. A., Amponsah, I. K., Annan, K. and Fleischer, T. C. (2014). Nutritive potential of a polyherbal preparation from some selected Ghanaian Herbs. Journal of Natural Product and Plant Resources, 4 (3):77-81.
    • Mensah A. Y., Mireku, E. A., Mensah, M. L. K., Oppong-Damoah, A. and Amponsah, I. K. (2014). Anti-inflammatory and antioxidant activities of Commelina diffusa (Commelinaceae). World Journal of Pharmaceutical Sciences, 2(10): 1159-1165.
    • Mensah, A., Mireku E., Mensah M. L. K. and Amponsah I. K. (2014). Some neurological effects of the ethanolic stem bark extract  of Cussonia  bancoensis  Aubrev and  Pellgr (Araliaceae). Journal of Pharmacognosy and Phytochemistry, 2 (6): 101-106
    • Ekuadzi, E., Dickson, R. A., Fleischer, C., Amponsah, I. K., Pistorius, D. and Oberer, L. (2014). Chemical constituents from Gouania longipetala and Glyphaea  brevis. Natural Product Research, 28(15):1210-3.

    2013

    • Amponsah, I. K., Fleischer, C., Dickson, R. A., Annan, K. and Thoss, V. (2013). Evaluation of the anti-inflammatory and antioxidant activity of Furanocoumarins and Sterolin from the stem bark of Ficus exasperata Vahl (Moraceae). Journal of Scientific and Innovative Research, 2 (5): 880-887.
    • Amponsah, I. K., Fleischer, T. , Annan, K., Dickson, R. A., Mensah, A. Y. and Sarpong, F. M. (2013). Anti-inflammatory, antioxidant and antimicrobial activity of the stem bark extract and fractions of Ficus exasperata Vahl. (Moraceae). Journal of Pharmacognosy and Phytochemistry, 2 (3): 38-44.
    • Annan, K., Dickson, R. A., Amponsah, I. K. and Nooni, I. K. (2013). The heavy metal contents of some selected medicinal plants sampled from different geographical location. Pharmacognosy research, 5:103-8.
    • Annan, K., Amponsah, I. K., Sarpong, F. M., Nooni, I. K. and Jato J. (2013). Pharmacognostic Evaluation and Physicochemical Analysis of Paullinia pinnata L. (Sapindaceae). Journal of Pharmacognosy and Phytochemistry, 2(2):203-208.
    • Koffuor, G. A., Ainoonson, G. K., Amponsah, I. K., Addotey, J. N., Asiamah, E. A., Akuffo, S. K., Adutwum, K. and Bandoh, R. F. (2013). Anti-ulcerant activity of an aqueous fruit extract of Musa x para-disiaca on acetic acid-induced gastric ulceration in ICR Mice. Journal of Medical and Biomedical Sciences, 2(2): 30-39.
    • Koffuor G. A., Ainooson, G. K., Addotey, J. N. A., Amponsah, I. K., Afriyie, V. A. and Tutu, R. (2013). Preliminary pharmacological investigation of the ischuretic property and safety of a hydro-ethanolic extract of Amaranthus spinosus (Fam: Amaranthaceae). International Journal of Basic & Clinical Pharmacology, 2(5): 517-527.
    • Sarpong, F. M., Fleischer, T. C., Annan, K, Amponsah, I. K., Dickson, R. A. and Mensah M. L. K. (2013). Anti-inflammatory and anti-oxidant ecdysteroid and Fatty acids from the roots of Palisota hirsute K.Schum (Commelinaceae). International Journal of Pharmacognosy and Phytochemistry, 28(2):1159-1165.
    • Koffuor, G. A., Ameyaw, E.O., Oppong, K. J., Amponsah, I. K., Sunkwa, A., Semenyao, S. A. (2013). Analgesic activity of Pet-ether, Aqueous and Hydro-ethanolic leaf extracts of Aspilia africana (PERS) C.D. ADAMS (Asteraceae) in rodents. International Research Journal of Pharmacy, 4(7): 39-45.
    • K. Annan, R. A. Dickson, K. Sarpong, C. Asare, K. Amponsah, and E. Woode. (2013). Antipyretic activity of Polyalthia longifolia Benth. & Ho F. Var.Pendula (Annonaceae), on lipopolysaccharide-induced fever in rats. Journal of Medical and Biomedical Sciences, 2(1):8-12.

    2012

    • Annan, K., Sarpong, K., Asare, C., Dickson, R., Amponsah, K. I., Gyan, B., Ofori, M. and Gbedema, S. Y. (2012). In vitro anti-plasmodial activity of three herbal remedies for malaria in ghana: Adenia cissampeloides (Planch.) Harms, Terminalia ivorensis A. Chev, and Elaeis guineensis Jacq. Pharmacognosy Research, 4(4): 225-229.
    • Rita A. Dickson, Kofi Annan, Theophilus C. Fleischer, Isaac K. Amponsah, Kwabena Nsiah and J. A.  Oteng.  (2012).  Phytochemical  Investigations and  Nutritive  Potential of  Eight Selected Plants from Ghana. Journal of Pharmacy and Nutrition Sciences, 2(2): 172-17.

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