Dr. Michael Ntim

Lecturer


Dept: Physiology
School of Medical Sciences (Old site)
Department of Physiology
Room 10

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Research Areas/Interests

Details currently not available!


Publications

    List of Publications


    1.  Owusu-Boateng G, Ntim M and Plange-Rhule J. Ambient air quality in the Chirano gold mines limited,
    Bibiani Ghana. Global Advanced Research Journal of Physical and Applied Sciences Vol. 2 (2) pp. 032-
    038, September 2013.

    2.  M. Ntim, G. Owusu-Boateng, J. Plange-Rhule.  Air quality and the lung function of communities in the
    concessional area of the Chirano Gold Mines Limited, Bibiani-Ghana. American Journal of Scientific And
    Industrial Research 2013, 4(5):479-488.

    3.  Gbenga  Ogedegbe, Jacob  Plange-Rhule, Joyce  Gyamfi,  William  Chaplin,  Michael  Ntim, Kingsley
    Apusiga, Kiran Khurshid, Richard Cooper. A cluster-randomized trial of task shifting and blood pressure
    control in Ghana: Study protocol, Implementation Science 9(1):73 · June 2014

    4.  Iwelunmor J, Gyamfi J, Plange-Rhule J, Blackstone S, Quakyi NK, Ntim M, Zizi F, Yeboah-Awudzi K,
    Nang-Belfubah  A, Ogedegbe  G.  Exploring  stakeholders'  perceptions of  a  task-shifting  strategy  for
    hypertension control in Ghana: a qualitative study. BMC Public Health. 2017 Feb 21;17(1):216.

    5.  Gyamfi J, Plange-Rhule J, Iwelunmor J, Lee D, Blackstone SR, Mitchell A, Ntim M, Apusiga K, Tayo B,
    Yeboah-Awudzi  K,  Cooper  R,  Ogedegbe  G.  Training  nurses  in  task-shifting  strategies  for  the
    management and control of hypertension in Ghana: a mixed-methods study. BMC Health Serv Res.
    2017 Feb 2;17(1):104. Erratum in: BMC Health Serv Res. 2017 Mar 17;17 (1):216.

    6.  Ogedegbe, G., Plange-Rhule, J., Gyamfi, J., Chaplin, W., Iwelunmor, J., Ntim, M., … Cooper, R. (2017).
    [LB.03.07] Comparative effectiveness cluster-randomized trial of a nurse-led task-shifting strategy for hypertension control versus provision of health insurance coverage in CHCS in Ghana. Journal of Hypertension, 35, e78.

    7.  Blackstone, S., Iwelunmor, J., Plange-Rhule, J., Gyamfi, J., Quakyi, N. Kofi, Ntim, M., Addison, A.,
    Ogedegbe, G. (2017). “I believe high blood pressure can kill me:” using the PEN-3 Cultural Model to understand patients’ perceptions of an intervention to control hypertension in Ghana. Ethnicity & Health, 1–14.

    8.  Blackstone, S., Iwelunmor, J., Plange-Rhule, J., Gyamfi, J., Quakyi, N. K., Ntim, M., & Ogedegbe, G.
    (2017). Sustaining Nurse-Led Task-Shifting Strategies for Hypertension Control: A Concept Mapping Study to Inform Evidence-Based Practice. Worldviews on Evidence-Based Nursing, 14(5), 350–357.

    9.  Gyamfi, J., Plange-Rhule, J., Iwelunmor, J., Lee, D., Blackstone, S. R., Mitchell, A., Ntim M., Apusiga
    K., Tayo B., Yeboah-Awudzi K., Cooper R., Ogedegbe, G. (2017). Training nurses in task-shifting
    strategies for the management and control of hypertension in Ghana: a mixed-methods study. BMC
    Health Services Research, 17(1).

    10. Ogedegbe G, Plange-Rhule J, Gyamfi J, Chaplin W, Ntim M, Apusiga K, et al. (2018) Health insurance
    coverage with or without a nurse-led task-shifting strategy for hypertension control: A pragmatic cluster randomized trial in Ghana. PLoS Med 15(5): e1002561.6

    11. Wang, B., Wu, Q., Lei, L., Sun, H., Ntim, M., Zhang, X., Wang Y., Zhang Y., Ge B., Wu X., Wang Y., Xin Y., Zhoa J., Li, S. (2018). Long-term social isolation inhibits autophagy activation, induces postsynaptic dysfunctions and impairs spatial memory. Experimental Neurology. Vol. 311 (2019) 213-224.

    12. Frank Botsi Micah, Bernard Cudjoe Nkum, Michael Ntim. Lifestyle Risk Factors in Hospital Attendants in Kumasi, Ghana: Cross-Sectional Study. Open Science Journal of Clinical Medicine. Vol. 6, No. 3, 2018, pp. 15-23.

    13. Walana, W., Wang, J., Yabasin, I.B., Ntim, M., Kampo, S., Al-Azab, M., Elkhider, A., Dogkotenge Kuugbee, E., Cheng, J-w., Gordon, J.R., Li, F., IL-8 analogue CXCL8 (3-72) K11R/G31P, modulates LPS-induced inflammation via AKT1-NF-kβ and ERK1/2-AP-1 pathways in THP-1 monocytes, Human Immunology (2018).

    14. Li Q, Wu X, Na X, Ge B, Wu Q, Guo X, Ntim M, Zhang Y, Sun Y, Yang J, Xiao Z, Zhao J and Li S (2019)  Impaired  Cognitive  Function  and  Altered  Hippocampal  Synaptic  Plasticity  in  Mice  Lacking Dermatan Sulfotransferase Chst14/D4st1. Front. Mol. Neurosci. 12:26.

    15. Kampo S, Afful AP, Mohammed S, Ntim M, Buunaaim ADB, Anabah TW. Sub-hypnotic dose of propofol as antiemetic prophylaxis attenuates intrathecal morphine-induced postoperative nausea and vomiting, and  pruritus  in  parturient  undergoing  cesarean  section  — a  randomized  control  trial.  BMC Anesthesiology. 2019;19(1):177.

    16. Zhang Xinjun, Li Zhaoxia, Xu Caiming, Michael Ntim, Wang Baocheng. Clinical Journal of Human Sexuality. 2020, 29:2

    17. Gyamfi, J., Allegrante, J.P., Iwelunmor, J., Williams, O., Plange-Rhule, J., Blackstone, S., Ntim, M., Apusiga, K., Peprah, E. and Ogedegbe, G., 2020. Application of the Consolidated Framework for Implementation Research to examine nurses’ perception of the task shifting strategy for hypertension control trial in Ghana. BMC health services research, 20(1), p.65.

    18. Xu, C., Sui, S., Shang, Y., Yu, Z., Han, J., Zhang, G., Ntim, M., Hu, M., Gong, P., Chen, H. and Zhang, X., 2020. The landscape of immune cell infiltration and its clinical implications of pancreatic ductal adenocarcinoma. Journal of Advanced Research.

    19. Ntim M, Li QF, Zhang Y, Liu XD, Li N, Sun HL, Zhang X, Khan B, Wang B, Wu Q, Wu XF et al. TRIM32 Deficiency Impairs Synaptic Plasticity by Excitatory-Inhibitory Imbalance via Notch Pathway. Cerebral Cortex. 2020 Mar 26.

    20. Wu, Q., Wang, B., Li, Q.F., Zhang, X., Ntim, M., Wu, X.F., Li, N., Zhu, D.D., Jiang, R., Yang, J.Y. and Yuan, Y.H., 2020. SRC-1 Knockout Exerts No Effect on Amyloid β Deposition in APP/PS1 Mice. Frontiers in aging neuroscience, 12, p.145.

    21. Sui, S., An, X., Xu, C., Li, Z., Hua, Y., Huang, G., Sui, S., Long, Q., Sui, Y., Xiong, Y. and Ntim, M., 2020. An immune cell infiltration-based immune score model predicts prognosis and chemotherapy effects in breast cancer. Theranostics, 10(26), p.11938.

    22. Li, Q., Zhang, Y., Ge, B.Y., Li, N., Sun, H.L., Ntim, M., Sun, Y.P., Wu, X.F., Yang, J.Y. and Li, S., 2020. GPR50 Distribution in the Mouse Cortex and Hippocampus. Neurochemical Research, 45(10), pp.2312- 2323.7

    23. Wu, Q., Li, Q., Zhang, X., Ntim, M., Wu, X., Li, M., Wang, L., Zhao, J. and Li, S., 2020. Treatment with Bifidobacteria can suppress Aβ accumulation and neuroinflammation in APP/PS1 mice. Peer J, 8, p.e 10262.

    24. Sanches JGP, Song B, Zhang Q, Cui X, Yabasin IB, Ntim M, Li X, He J, Zhang Y, Mao J, Lu Y and Li L (2021) The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway. Front. Oncol. 11:637298.

    25. Wu Q, Wang B, Ntim M, Zhang X, Na XY, Yuan YH, Wu XF, Yang JY, Li S. SRC-1 Deficiency Increases Susceptibility of Mice to Depressive-Like Behavior After Exposure to CUMS. Neurochemical research. 2021 Apr 21:1-4.

    26. Xu, C., Luo, Y., Ntim, M., Quan, W., Li, Z., Xu, Q., Jiang, L., Zhang, J., Shang, D., Li, L. and Zhang, G., 2021. Effect of emodin on long non?coding RNA?mRNA networks in rats with severe acute pancreatitis?induced acute lung injury. Journal of Cellular and Molecular Medicine, 25(4), pp.1851-1866.

    27. Liu, S., Wang, Z., Ntim, M., Han, J., Jiang, X., Fang, C., Xu, C. and Zhang, J., 2022. Prediction of Survival Rate and Chemotherapy Effect by an Immune Score Model in Colorectal Cancer. BioMed Research International, 2022.

    28. Ba-Alwi, N.A., Aremu, J.O., Ntim, M., Takam, R., Msuya, M.A., Nassor, H. and Ji, H., 2022. Bacteriological Profile and Predictors of Death Among Neonates With Blood Culture-Proven Sepsis in a National Hospital in Tanzania—A Retrospective Cohort Study. Frontiers in Pediatrics, 10, p.797208.

    29. Zhu, D.D., Yang, G., Huang, Y.L., Zhang, T., Sui, A.R., Li, N., Su, W.H., Sun, H.L., Gao, J.J., Ntim, M. and Guan, R.X., 2022. AQP4-A25Q Point Mutation in Mice Depolymerizes Orthogonal Arrays of Particles and Decreases Polarized Expression of AQP4 Protein in Astrocytic Endfeet at the Blood–Brain Barrier. Journal of Neuroscience, 42(43), pp.8169-8183.

    30. Wang, B., Ntim, M., Xia, M., Wang, Y., Lu, J.C., Yang, J.Y. and Li, S., 2022. Long-Term Social Isolation- Induced Autophagy Inhibition and Cell Senescence Aggravate Cognitive Impairment in D (+) Galactose- Treated Male Mice. Frontiers in Aging Neuroscience, 14, p.777700.

    31. Wang, B., Chen, D., Jiang, R., Ntim, M., Lu, J., Xia, M., Yang, X., Wang, Y., Kundu, S., Guan, R. and Li, S., 2022. TIP60 buffers acute stress response and depressive behaviour by controlling PPARγ-mediated transcription. Brain, Behavior, and Immunity, 101, pp.410-422.

    32. Yuan, D.J., Yang, G., Wu, W., Li, Q.F., Xu, D.E., Ntim, M., Jiang, C.Y., Liu, J.C., Zhang, Y., Wang, Y.Z. and Zhu, D.D., 2022. Reducing Nav1. 6 expression attenuates the pathogenesis of Alzheimer's disease by suppressing BACE1 transcription. Aging Cell, 21(5), p.e13593.

    33. Wang, B., Yang, X., Lu, J., Ntim, M., Xia, M., Kundu, S., Jiang, R., Chen, D., Wang, Y., Yang, J.Y. and Li, S., 2022. Two-hour acute restraint stress facilitates escape behavior and learning outcomes through the activation of the Cdk5/GR P S211 pathway in male mice. Experimental Neurology, 354, p.114023.

    34. Wang, Y., Xia, M., Lu, J., Wang, T., Zhang, X., Ntim, M. and Wang, B., 2023. TIP60 mediates stress- induced hypertension via promoting glutamatedmPFC-to-vCA1 release. Clinical and Experimental Hypertension, 45(1), p.2259130.


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